Lieping Chen Recruited to YCC 
I am happy to announce that Lieping Chen, MD, PhD has accepted a position as Director of Cancer Immunology at Yale Cancer Center. Lieping is internationally known for his leadership in cancer immunobiology and his appointment at Yale Cancer Center will ensure Yale continues as a leader in cancer immunobiology, not only in our basic science laboratories but in our clinics as well. His commitment to translating basic discoveries from the lab and developing new strategies to treat cancer using novel biologics in clinical trials will serve as a model for our translational research initiatives. Lieping joins us on September 1 from Johns Hopkins University School of Medicine.
New York
Magazine Honors Best Docs
Congratulations to the 28 Yale Cancer Center physicians who were recognized on the 2010
New York Magazine Best Doctors list.
The following members of Yale Cancer Center were recognized in the 2010 publication:
Allen Bale John Persing
Jean Bolognia Richard Peschel
John Colberg Joseph Piepmeier
Thomas Duffy Carrie Redlich
Richard Edelson Kenneth Roberts
Harris Foster Ronald Salem
Gary Friedlaender Clarence Sasaki
Silvio Inzucchi Peter Schwartz
John Kveton Richard Stahl
David Leffell Hugh Taylor
Walter Longo J. Grant Thomson
Thomas Lynch Robert Udelsman
Shirley McCarthy Jeffrey Weinreb
Pasquale Patrizio Lynn Wilson
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Peter Roche will join the Yale School of Medicine development office as a Major Gifts Officer assigned to Yale Cancer Center on July 1. Peter was most recently responsible for the 50th Reunion gift campaigns at Yale University, and skillfully managed a host of reunion appeals, beginning with the 30th Reunion.
At Yale Cancer Center, Peter will manage a portfolio of major gift prospects and donors and work closely with YCC faculty and leadership to fundraise for the cancer center's highest priorities.
Jason Wilkin, PhD , a fellow in the laboratory of Nita Maihle, PhD, was recently awarded a travel grant from the New York Academy of Sciences to present at their meeting, "Towards Personalized Cancer Medicine" in May in Barcelona, Spain. Dr. Wilken presented,
Trastuzumab Resistance--More than Just Proliferation? , during the Hot Topics session of the meeting.
Two Yale Cancer Center members were awarded a 2010
Women's Health Research at Yale (WHRY) award to support their ongoing research initiatives:
Dr. Alessandro Santin intends to develop a novel mechanism for advancing chemotherapy for ovarian cancer by exploring the possibility of delivering a tumor-destroying chemotherapy using nanoparticles. Dr. Santin's work is co-funded by
WHRY and
Yale Cancer Center .
Dr. Julie Ann Sosa received a grant from
WHRY to develop an innovative approach to treat hypoparathyroidism, a condition in which the parathyroid glands malfunction, leading to low blood-calcium levels. Her research will induce human embryonic stem cells to develop into parathyroid cells that would secrete a parathyroid hormone and maintain normal calcium balance potentially leading to a cure for hypoparathyroidism.
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Breast Milk Protein Linked to Poorer Breast Cancer Survival in Younger Women
In a study that sheds light on why breast cancer may be deadlier for premenopausal women, a research team led by John Wysolmerski, MD, a member of the Yale Cancer Center Signal Transduction Research Program, has linked breast cancer survival with levels of a transport protein that regulates milk production in mammary glands. The paper is published in the
Proceedings of the National Academy of Sciences.
Prenatal Exposure To BPA and DES May Increase Breast Cancer Risk
Exposure in the womb to chemicals like Bisphenol-A (BPA) and Diethylstilbestrol (DES) can increase an offspring's risk of breast cancer, researchers at Yale School of Medicine report in a study published in current issue of
Hormones and Cancer , a journal of The Endocrine Society. The research was led by Yale Cancer Center Genetics and Genomics Research Program member Hugh Taylor, MD.
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Department of Defense Peer Reviewed Cancer Research Program
The
Peer Reviewed Cancer Research Program Translational New Investigator Award
is new for fiscal year 2010 and supports the development of translational research partnerships between two independent investigators. Within the partnership, one member must be a laboratory scientist and the other must be a clinician. This award is intended to support a mentoring partnership between a new investigator and an established research program.
The Peer Reviewed Cancer Research Program Idea Award is intended to promote the exploration of ideas that are still in the early stages of development yet have the potential to yield high-impact results and open new avenues of investigation. This mechanism supports conceptually innovative, high-risk/high-reward research that could ultimately lead to critical discoveries or major advancements. Preliminary data are not required. However, research projects should include a well-formulated, testable hypothesis based on a strong scientific rationale.
A pre-application consisting of a two page narrative and biosketches is due July 14, 2010. Learn More >>
Komen for the Cure Promise Grant
Promise Grants are intended support two or three principal investigators and an investigative team that brings together and integrates laboratory, clinical and/or public health disciplines to conduct several related projects, the results of which converge to answer critical questions. Relevant research applications may include components that focus on breast cancer biology; genetics; epidemiology; prevention; detection; risk assessment; biomarkers of risk, disease burden, and/or treatment response or resistance; novel therapeutics; lifestyle interventions with the potential to affect disease outcomes (e.g., incidence and/or mortality); and novel approaches that enhance understanding of the breast cancer disease process. Integrated programs of research projects addressing critical challenges in population disparities in breast cancer outcomes are of special interest and may receive funding priority.
Pre-Application Due July 26, 2010, by 8 p.m., EDT Learn More >>
Yale Scholar Awards Program
Internal Deadline: June 18, 2010
Pew Scholars Program in the Biomedical Sciences
- For basic and clinical investigations relevant to the advancement of human health. Strong preference for creative and innovative approaches; risk-taking is encouraged.
- For individuals who will hold a full-time appointment at the rank of assistant professor by November 1, 2010, but who will not have been in such an appointment form more than 3 years as of July 1, 2011.
- $60,000 per year for 4 years. ($240,000)
Learn More >>
Gabriells's Angel Foundation for Cancer Research
Medical Research Grants - To support the conduct of innovative and insightful medical research on the hematologic malignancies.
- Funds are provided for clinical or basic science research that will lead to novel therapeutic approaches that could replace, or be used in combination with existing effective therapies for patients with leukemia, lymphoma, and related cancers. Such therapeutic approaches could include alternative or complementary medicine.
- For junior faculty with the MD or PhD.
Learn More >>
Searle Scholars Program - To pursue independent research careers in biochemistry, cell biology, genetics, immunology, neuroscience, pharmacology, or related areas in chemistry, medicine, and the biological sciences.
- For assistant professors who began their first appointment on or after July 1, 2009.
- $100,000 per year for 3 years. ($300,000)
Learn More >>Richard & Susan Smith Family Foundation Smith Family Awards for Excellence in Biomedical Research - To support promising young scientists engaged in new and innovative research in all areas of basic biomedical science.
- Investigators in physics, chemistry, and engineering with biomedical research projects are also encouraged to apply.
- Clinical research is beyond the scope of this program.
- Candidates must be full-time independent investigators who have completed not more than 2 years of a junior faculty appointment and will have been appointed to their first independent appointment between July 1, 2008 and December 1, 2010.
- $300,000 to be used over a period of 3 years. ($300,000)
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Recent Publications
Biology of Colorectal Cancer.
Saif MW, Chu E.
Cancer J. 2010 May/June;16(3):196-201.
Read More >>
Serum response factor is an essential transcription factor in megakaryocytic maturation.
Halene S, Gao Y, Hahn K, Massaro S, Italiano JE Jr, Schulz V, Lin S, Kupfer GM, Krause DS.
Blood. 2010 Jun 4.
Read More >>
Imaging requirements in the practice of pulmonary metastasectomy.
Detterbeck FC, Grodzki T, Gleeson F, Robert JH.
J Thorac Oncol. 2010 Jun;5(6 Suppl 2):S134-9.
Read More >>
Macrophage migration inhibitory factor (MIF): A promising biomarker.
Grieb G, Merk M, Bernhagen J, Bucala R.
Drug News Perspect. 2010 May;23(4):257-64.
Read More >>
Selective and effective killing of angiogenic vascular endothelial cells and cancer cells by targeting tissue factor using a factor VII-targeted photodynamic therapy for breast cancer.
Hu Z, Rao B, Chen S, Duanmu J.
Breast Cancer Res Treat. 2010 Jun 1.
Read More >>
Correlation between gene expression profiling-based molecular and morphologic classification of breast cancer.
Tavassoli FA.
Int J Surg Pathol. 2010 Jun;18(3 Suppl):167S-169S.
Read More >>
Targeted therapy for thyroid cancer: An updated review of investigational agents.
Deshpande HA, Gettinger SN, Sosa JA.
Curr Opin Investig Drugs. 2010 Jun;11(6):661-8.
Read More >>
The plasma membrane calcium-ATPase 2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer.
VanHouten J, Sullivan C, Ryoo T, Camp R, Rimm D, Chung G, Wysolmerski J.
Proc Natl Acad Sci USA, 2010 Jun 4.
Read More >>
Incorporating gene co-expression network in identification of cancer prognosis markers.
Ma S, Shi M, Li Y, Yi D, Shia BC.
BMC Bioinformatics. 2010 May 20;11(1):271.
Read More >>
High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology.
Anagnostou VK, Lowery FJ, Zolota V, Tzelepi V, Gopinath A, Liceaga C, Panagopoulos N, Frangia K, Tanoue L, Boffa D, Gettinger S, Detterbeck F, Homer RJ, Dougenis D, Rimm DL, Syrigos KN.
BMC Cancer. 2010 May 9;10:186.
Read More >>
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Inside Yale Cancer Center
Oncology Congress 2010
Yale Cancer Center is a partner for this year's congress. Take advantage of the special registration rate.
Subscribe to Yale Cancer Center Answers on iTunes
Yale Cancer Center's weekly radio program on CT Public Radio is ranked number 2 in the world for cancer programs on iTunes.
Learn More >>
Cancer Bytes
Hosted by Ellen Matloff, listen to the interviews online.
Learn More >>
Yale Cancer Center Grand Rounds
Video presentations from Yale Cancer Center members are now available online.
Learn More >>
DirectConnect Archives
Learn More >>
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Events
June 11; 12:30 PM
Molecular Virology Research Conference
SHM I-116
Antibody-Recruiting Small Molecules to Target HIV and Other Pathogens
David A. Spiegel, MD, PhD
Learn More >>
June 13; 6:00 PM
Yale Cancer Center Answers
WNPR 90.5
Breast Cancer
Gina Chung, MD
Learn More >>
June 16; 1:00 PM
Hematology Seminar Series
SHM I-304
Hematopoietic Stem Cell Competition
Ruslan Medzhitov, PhD
Learn More >>
June 17; 6:00 PM
Updates and Innovations in Esophageal Cancer
Mystic Marriot
The Yale Cancer Center Esophageal Cancer Program
Learn More >>
June 20; 6:00 PM
Yale Cancer Center Answers
WNPR 90.5
Skin Care for Cancer Patients
Jennifer Choi, MD
Learn More >>
June 22; 12:00 PM
Yale Cancer Center Grand Rounds
55 Park Street
Molecular Alterations that Predict Premalignancy in Breast Cancer
Thea D. Tisty, PhD
Learn More >>
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Submissions
Please submit your recent publication and grant announcements to:
Renee Gaudette
Director, Public Affairs and Marketing
renee.gaudette@yale.edu
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