Sarah Cannon Research Institute, YCC, and SCH Announce Intent to Collaborate
I am pleased to announce that we are finalizing plans to collaborate with the Sarah Cannon Research Institute (SCRI), the nation's premier clinical research institute, to enhance clinical trial opportunities at Yale Cancer Center.
As part of the collaboration, SCRI would meet regularly with us to discuss strategic scientific priorities for certain tumor types and to develop clinical research protocols. I look forward to sharing the full details of our agreement later this month.
Peter Marks and Marcella Nunez-Smith Recognized for Outstanding Teaching
Dean Alpern recognized two Yale Cancer Center members during the Yale School of Medicine Commencement ceremonies with awards for excellence in teaching.
Dr. Peter Marks, Associate Professor of Hematology and Chief Clinical Officer for Smilow Cancer Hospital, was awarded the
Charles W. Bohmfalk Prize for teaching in the basic sciences and Dr. Marcella Nunez-Smith, Assistant Professor of Medicine and a member of the Yale Cancer Center Prevention and Control Research Program, received the Leah M. Lowenstein Award for excellence in the promotion of humane and egalitarian medical education.
Please join me in congratulating Peter and Marcella for their outstanding accomplishments.
Anne Chiang recruited to Lead Network Development
Anne Chiang, MD, PhD will join Yale Cancer Center and Smilow Cancer Hospital on October 1 as an Assistant Professor of Medical Oncology and Chief Medical Officer for the Smilow Cancer Hospital Network.
Dr. Chiang's primary responsibility will be to lead our efforts to develop a network of community-based care facilities throughout Connecticut and to oversee those relationships.
Dr. Chiang was previously practicing at Connecticut Hematology & Oncology in New Milford, CT.
She received her PhD from Harvard University and her medical degree from Cornell Medical College.
Prior to private practice, Dr. Chiang did her internship and residency at NY Presbyterian Hospital and a Fellowship at Memorial Sloan-Kettering Cancer Center.
Dr. Chiang is currently participating in the ASCO Leadership Development Program.
Please Join us for the Annual ASCO Review
Yale Cancer Center members receive complimentary registration for our annual ASCO Review, CME Conference, on Wednesday, June 22 at Yale's West Campus.
The agenda includes presentations from Yale Cancer Center faculty on the newest updates from this month's ASCO meeting in Chicago, including a highlight from Julie Sosa's presentation on the FACT Trial, and a keynote address by Dan DiMaio.
We appreciate the time and effort that so many of our members put into making the annual Yale Cancer Center scientific retreat and the YCC-UCL joint retreat a success last week. A special thank you to Susan Silva and Hilary Prosnitz for all of their hard work planning both events. If you attended one or both of the retreats, please take a few minutes to provide us with some feedback.
Chênevert Named Chair of the Yale Cancer Center Advisory Board
Yale Cancer Center is pleased to announce the appointment of Louis Chênevert as Chairman of the Center's Advisory Board.
Mr. Chênevert is Chairman and Chief Executive Officer of United Technologies Corp. and has been a member of Yale Cancer Center's Advisory Board since 2001.
In addition, he served as co-chairman of the Campaign Committee for Smilow Cancer Hospital at Yale-New Haven from 2007 - 2010.
The Yale Cancer Center Director's Advisory Board is a group of active volunteers who are knowledgeable and informed advocates for the Center. This advocacy includes actively promoting the mission of Yale Cancer Center, as well as participation in fundraising activities intended to provide financial support for Yale Cancer Center.
Smilow Cancer Hospital
Advanced Vascular Imaging Services Available
Smilow Cancer Hospital is now offering full service non-invasive vascular ultrasound and physiological testing on the second floor of the hospital in the diagnostic imaging suites. Led by Leslie Scoutt, MD, screening for varicose veins, venous insufficiency, carotid ultrasound, transcranial doppler aortic aneurysms, renal artery stenosis, lower and upper arterial bypass grafts, dialysis access transplant, hepatic/TIPS, portal, mesenteric vascular imaging, lower and upper venous Doppler for DVT, vein mapping, and segmental pressure ABI/PVR is available.
To schedule a patient exam, please call (203) 688-2433.
Ruslan Medzhitov, PhD, a member of the Yale Cancer Center Cancer Immunology Program, is one of three scientists awarded the prestigious Shaw Prize in Life Science and Medicine for 2011. Medzhitov has made groundbreaking contributions to the understanding of innate immunity, which provides immediate defense against infection.
Meena Moran, MD, has recently been nominated to join the editorial board of the Journal of Clinical Oncology (JCO).
Dr. Moran is an Associate Professor of Therapeutic Radiology and a member of the Yale Cancer Center Radiobiology & Radiotherapy Research Program.
Anthony Koleske, PhD and Titus Boggon, PhD, both members of the Yale Cancer Center Signal Transduction Program, are the recipients of a 2011 Women's Health Research at Yale Pilot Grant, co-funded by Yale Cancer Center. Their research will focus on new drug development to selectively target breast cancer metastasis.
Department of Defense Lung Cancer Research Program
Supports highly innovative, untested, potentially groundbreaking concepts in lung cancer
Emphasis is on innovation
Early Investigator Synergistic Idea Award
Supports collaborations between two independent investigators early in their careers who address an innovative and high impact lung cancer research question from synergistic and complementary perspectives
This award is designed to promote collaborations between a clinician and laboratory scientist
Investigator Initiated Translational Research Award
Supports translational research that will accelerate the movement of promising ideas in lung cancer into clinical applications
Must include preliminary data that is relevant to lung cancer and the proposed project
This award does not support clinical trials, but may support correlative studies that are associated with an existing clinical trial and projects that develop endpoints for clinical trials
Promising Clinician Research Award
Supports a research project performed by promising physician-researchers
This award is intended to prepare physicians with clinical duties and/or responsibilities for an independent and active career in lung cancer research
The NCI has established an Etiologic and Early Marker Studies (EEMS) Program, which includes a biospecimen repository for biospecimens collected from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. The PLCO Biorepository contains approximately 2.7 million biologic specimens, including blood specimens collected from intervention participants during their six trial screening years and buccal cell specimens collected from control participants. These specimens were thus collected before diagnosis of cancer and may be of great value for investigators studying early detection biomarkers.
Applications to access specimens are accepted twice per year; the next deadline is July 15.
An integrated approach to segmentation and nonrigid registration for application in image-guided pelvic radiotherapy.
Lu C, Chelikani S, Papademetris X, Knisely JP, Milosevic MF, Chen Z, Jaffray DA, Staib LH, Duncan JS.
Med Image Anal. 2011 May 20.
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Ongoing challenges in the endoscopic management of hilar cholangiocarcinoma.
Aslanian HR, Jamidar PA.
Dig Dis Sci. 2011 May;56(5):1255-6.
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Developing a Scale to Measure Parental Worry and Their Attitudes Toward Childhood Cancer After Successful Completion of Treatment: A Pilot Study.
J Pediatr Oncol Nurs. 2011 Jun 2.
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Expression of αV-Integrins in Uterine Serous Papillary Carcinomas; Implications for Targeted Therapy With Intetumumab (CNTO 95), a Fully Human Antagonist Anti-αV-Integrin Antibody.
Bellone M, Cocco E, Varughese J, Bellone S, Todeschini P, El-Sahwi K, Carrara L, Guzzo F, Schwartz PE, Rutherford TJ, Pecorelli S, Marshall DJ, Santin AD.
Int J Gynecol Cancer. 2011 May 30.
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Inhibition of Aurora A kinase induces cell cycle arrest in epithelial ovarian cancer stem cells by affecting NFĸB pathway.
Chefetz I, Holmberg JC, Alvero AB, Visintin I, Mor G.
Cell Cycle. 2011 Jul 1;10(13).
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Patient Preferences After Endoscopic Ultrasound With Fine Needle Aspiration (EUS-FNA) Diagnosis of Pancreas Cancer: Rapid Communication Valued Over Long-Term Relationships.
Siddiqui UD, Rossi F, Padda MS, Rosenthal LS, Aslanian HR.
Pancreas. 2011 May 19.
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Efficacy of bevacizumab plus erlotinib versus erlotinib alone in advanced non-small-cell lung cancer after failure of standard first-line chemotherapy (BeTa): a double-blind, placebo-controlled, phase 3 trial.
Herbst RS, Ansari R, Bustin F, Flynn P, Hart L, Otterson GA, Vlahovic G, Soh CH, O'Connor P, Hainsworth J.
Lancet. 2011 May 28;377(9780):1846-54.
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Analysis of deoxyribonucleotide pools in human cancer cell lines using a liquid chromatography coupled with tandem mass spectrometry technique.
Zhang W, Tan S, Paintsil E, Dutschman GE, Gullen EA, Chu E, Cheng YC.
Biochem Pharmacol. 2011 May 18.
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Neoadjuvant Chemoradiation for Clinically Advanced Non-Small Cell Lung Cancer: An Analysis of 233 Patients.
Kim AW, Liptay MJ, Bonomi P, Warren WH, Basu S, Farlow EC, Faber LP.
Ann Thorac Surg. 2011 May 25.
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Countdown to the CCSG Submission
until our CCSG
grant is due on
September 25, 2012.