| Announcements
Yale Ranked 24 for Cancer Services in US News Rankings
Yale-New Haven Hospital has been named as one of the top hospitals in the United States, according to annual "America's Best Hospitals" rankings. Ranked in 12 of 16 specialties, cancer services at the medical center were ranked 24th in the nation.
Our reputation score increased and our overall score in the improved from 37.3 to 41.6. This is a direct reflection of the hard work and commitment of our clinical care providers and staff. The strong collaboration between Smilow Cancer Hospital at Yale-New Haven and Yale Cancer Center and our continued investment in cancer research and clinical care will ensure our sustained strength as a national leader in cancer care.
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Successful Developmental Therapeutics RetreatThank you to Karen Anderson and Roy Herbst for all of their efforts to plan the first Developmental Therapeutics Research Program Retreat last week. The format of the retreat allowed for great discussion among the presenters and attendees and I hope our other research programs will duplicate their interactive format.
Garth Powis D. Phil., Professor and Chairman of the Department of Experimental Therapeutics and Director of the Center for Targeted Therapy at The University of Texas MD Anderson Cancer Center, gave a keynote address on "Developing Cancer Drugs in Academia: A Novel PI-3-K Inhibitor." Additionally, speakers from Yale presented on recent research and discussed future initiatives for the Developmental Therapeutics Research Program.
Strategic Planning Retreat HeldThe leadership of Yale Cancer Center met last week to review our strategic plan, evaluate our progress on goals set in 2010, and summarize the Center's goals for the coming year. I appreciate the time and energy that YCC's directors put into the planning day and look forward to sharing our progress and goals over the coming months.
Peter Koo, PhD Joins Medical OncologyI am pleased to announce that Peter (Ja Seok) Koo, PhD will join the Yale Cancer Center faculty on October 1st as an Associate Professor of Medical Oncology. He will focus his laboratory research efforts on translational science, in close collaboration with Dr. Roy Herbst. Dr. Koo is currently an Associate Professor in the department of medical oncology (thoracic/head and neck) at MD Anderson Cancer Center. He is a principal investigator of an NCI funded project looking at the "Role of CREB in Lung Cancer Development."
Dr. Koo is also interested in identification of new therapeutic targets and development of new drugs for lung cancer treatment. Dr. Koo received his undergraduate and master's degree from Pusan National University in the Republic of Korea and his doctorate degree in biological chemistry from the University of North Carolina at Chapel Hill. He did his fellowship training at Duke University Medical Center. |
Notables Dr. Lynn Wilson has been named one of 21 members of the 2011 Fellows Class for the American Society for Radiation Oncology (ASTRO). He will receive his fellow designation at a ceremony during the society's 53rd annual meeting in Miami this October. Members of ASTRO are eligible to become a Fellow after they have been a member of the society for 15 years, given significant service to ASTRO, and have made a significant contribution to the field of radiation oncology. Learn More >> Lynnanne Selezan, RN and Sandy Cayo, RN, were nominated for CURE magazine's "2011 Extraordinary Healer Award for Oncology Nursing." Each year, CURE gives its readers the opportunity to nominate an oncology nurse who has exhibited extraordinary compassion, expertise and helpfulness. The list of nominees was published in the Summer issue of the magazine. Learn More >> Congratulations to the following employees of Yale Cancer Center who are recognized for milestone years of service in 2011 by Yale University: Lisa Arnel 5 years Saadia Aziz 5 years Emily Fenton 5 years Sharon Gould 20 years Jessica Jorge 5 years Robin Penney 15 years Von Potter 5 years Rhonda Pruzinsky 20 years Louise Salvati 5 years |
Employee Profile: Rocco Carbone The Employee Profile section is a new segment of DirectConnect included to recognize the diverse contributions made by Yale Cancer Center and Smilow Cancer Hospital staff have to meet our patient care, research, education, and outreach goals. Each issue will highlight a staff member, giving us the opportunity to learn about the people in our Cancer Center's community and how they contribute to our mission. The staff profiled are examples of the great work being done here, and the dedication and values we possess. To suggest someone to be profiled, please contact
Emily Fenton.Rocco Carbone Rocco Carbone, MS, has never been one to turn down a challenge in his career, so when he was asked to head up a Cell Processing Lab as part of the Clinical Trial Support Services (CTSS) core at Yale Cancer Center and Smilow Cancer Hospital, he jumped at the chance. Mr. Carbone assists in the collection of
biospecimen
s from patients from cancer clinical trials. He then performs whatever task is required for the particular protocol. This may include shipping the sample out to an analytical lab or to the study's sponsor, isolating subpopulations of cells, or saving and banking the specimen for future use. Biopsies are often collected to examine genetic markers, which help the physicians determine the best treatment.
Previously having worked in a cytometry lab at Yale, Mr. Carbone is no stranger to analyzing DNA or cell surface markers and working in the lab. Two years ago he celebrated his 25 anniversary with Yale and has been in his current position now for 3 years. When a new protocol is proposed, he meets with the Principal Investigator and sponsor company of the trial in order to fully understand what they want from the protocol and from his lab. Most of the drugs in these clinical trials are experimental. The basic research has been done, some of the safety profiles have been completed, and now researchers need to know how the drug acts once it is in the body. It is Mr. Carbone's job, with the help of Cindy Gianpaolo-Ostravage, a very skilled assistant, to collect samples which will be analyzed in other laboratories, both within and outside Yale, to determine how long and at what levels a drug remains in the body, and into which other molecules the drug is transformed.
"It is rewarding to know that we are indirectly helping patients and advancing clinical trial knowledge, which is so important. This role also allows us to stay up to date on all the clinical trials that are going on at Yale Cancer Center. The lab continues to grow as more and more clinical trials are being introduced, and that's a wonderful thing to see, especially knowing that I had a hand in transferring a potential cancer drug from the basic research lab into the clinic," explained Mr. Carbone.
Mr. Carbone was able to get the Cell Processing lab up and running before the first patient was seen at Smilow Cancer Hospital, which was no small feat. He was tasked with starting the lab basically from scratch and has watched it expand.
Rocco's supervisor, Dr. Lyndsay Harris, commented, "Quiet and unassuming, Rocco nonetheless stands out for his technical prowess and unvarnished devotion to scientific discovery.
Yale Cancer Center and Smilow Cancer Hospital owe a great deal to the stellar performance of Rocco Carbone."
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Funding and Award Opportunities
Avon Breast Health Outreach Program Grant (BHOP)The Avon BHOP plans to award one-year grants covering the funding period from January 1, 2012, through December 31, 2012. Approximately $5 million in competitive grant funds will be awarded to about 125 community-based programs and/or health care agencies. The majority of the grants will range from $30,000 to $60,000 per year, with most grants averaging $45,000 per year.
Application Deadline: August 26, 2011 CONquer canCER Now Grant : CONCERN Foundation
The sponsor will provide funding for researchers who
lack financial support for their first major research project in the areas of cancer genetics, cell biology, and immunology.
Application Deadline: September 8, 2011
Learn More >>
The Komen Career Catalyst GrantCareer Catalyst Research (CCR) Grants are intended to foster increased research independence of promising breast cancer researchers who are in the early stages of their faculty careers. These Grants provide support for research projects that have significant potential to advance our understanding of breast cancer and lead to reductions in breast cancer incidence and/or mortality within the next decade.
Application Deadline: August 30, 2011 Learn More >> Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research
Objectives:The sponsor provides an award to recognize outstanding achievements in clinical cancer research.
Eligibility: Candidacy is open to all cancer researchers who are affiliated with any institution involved in cancer research, cancer medicine or cancer-related biomedical science anywhere in the world. Such institutions include those in academia, industry or government. The award will be presented to an individual investigator. Institutions or organizations are not eligible for the award.
Funding: The winner of the 17th Annual AACR Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research will give a 50-minute lecture during the AACR 103rd Annual Meeting 2012, receive an honorarium of $10,000, and be given support for the winner and a guest to attend the Annual Meeting.
Application Deadline: October 11, 2011 Learn More >> |
Recent Publications
Graft-versus-Leukemia (GVL) against Mouse Blast-Crisis Chronic Myelogenous Leukemia (BC-CML) and Chronic-Phase Chronic Myelogenous Leukemia (CP-CML): Shared Mechanisms of T Cell Killing, but Programmed Death Ligands Render CP-CML and Not BC-CML GVL Resistant.
Matte-Martone C, Venkatesan S, Tan HS, Athanasiadis I, Chang J, Pavisic J, Shlomchik WD.
J Immunol. 2011 Jul 18.
Learn More >>
A unified framework for joint segmentation, nonrigid registration and tumor detection: application to MR-guided radiotherapy.
Lu C, Chelikani S, Duncan JS.
Inf Process Med Imaging. 2011;22:525-37.
Learn More >> Retraction to "A3' UTR KRAS variant as a biomarker of poor outcome and chemotherapy resistance in ovarian cancer" [Gynecol. Oncol. 120 (2011) S3].
Ratner E, Keane F, Yu H, Zelterman D, Rutherford T, Santin A, Schwartz P, Slack F, Levine D, Weidhaas J.
Gynecol Oncol. 2011 Jul;122(1):205.
Learn More >>
Radiation Resistance in Cancer Therapy: Meeting Summary and Research Opportunities: Report of an NCI Workshop held September 1-3, 2010.
Glazer PM, Grandis J, Powell SN, Brown JM, Helleday T, Bristow R, Powis G, Hill RP, Le QT, Pelroy R, Mohla S, Bernhard EJ.
Radiat Res. 2011 Jul 8.
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The role of epigenetic alterations in papillary thyroid carcinogenesis.
Eze OP, Starker LF, Carling T.
J Thyroid Res. 2011;2011:895470.
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In Utero Exposure to Diethylstilbestrol (DES) or Bisphenol-A (BPA) Increases EZH2 Expression in the Mammary Gland: An Epigenetic Mechanism Linking Endocrine Disruptors to Breast Cancer.
Doherty LF, Bromer JG, Zhou Y, Aldad TS, Taylor HS.
Horm Cancer. 2010 Jun;1(3):146-55.
Learn More >>
Genome-wide approaches for cancer gene discovery.
Lizardi PM, Forloni M, Wajapeyee N.
Trends Biotechnol. 2011 Jul 12.
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Defining the role of cooperation in early tumor progression.
Krepkin K, Costa J.
J Theor Biol. 2011 Jul 2;285(1):36-45.
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Disclosing medical errors: a practical guide and discussion of radiation oncology-specific controversies.
Evans SB, Decker R.
Int J Radiat Oncol Biol Phys. 2011 Aug 1;80(5):1285-8.
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Vesicular stomatitis virus has wide oncolytic activity against human sarcomas; rare resistance is overcome by blocking interferon pathways.
Paglino JC, van den Pol AN.
J Virol. 2011 Jul 6.
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Countdown to the CCSG Submission 431 days
until our CCSG
grant is due on
September 25, 2012.
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Inside Yale Cancer Center
In the News Read recent articles featuring experts from Yale Cancer Center. Learn More >>
Subscribe to Yale Cancer Center Answers on iTunes
Yale Cancer Center's weekly radio program on CT Public Radio is ranked number 2 in the world for cancer programs on iTunes. Subscribe to the show.
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Cancer Bytes
Hosted by Ellen Matloff, listen to the latest interview with Nathan: Advanced Colon Cancer at age 21 - Not your Average College Experience. Learn More >>
Yale Cancer Center Grand Rounds
Video presentations from Yale Cancer Center members are now available online.
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DirectConnect Archives
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Events
July 22; 10:00 AM Free Head and Neck Cancer Screening New Haven City Hall Learn More >> July 24; 6:00 PM Yale Cancer Center Answers
WNPR Cancer Risk and Genetics Joann Sweasy, PhD
Learn More >>
July 28; 9:00 AM
Therapeutic Radiology Grand Rounds
SCH LL Overview of Nuclear Medicine Services
David Cheng, MD, PhD Learn More >> July 31; 6:00 PM Yale Cancer Center Answers
WNPR Cancer Epidemiology Tongzhang Zheng, PhD
Learn More >> |
New Faculty Recruits (May 2009 - Present)
Anees Chagpar Surgical Oncology Sandy Chang Lab Medicine Anne Chiang Medical Oncology Lieping Chen Immunobiology Deborah Chirnomas Pediatric Oncology Suzanne Evans Therapeutic Radiology
Leonard Farber Medical Oncology Mark Faries Surgical Oncology
Bonnie Gould Rothberg Medical Oncology
Valentina Greco Genetics Stephanie Halene Hematology
Roy Herbst Medical Oncology Howard Hochster Medical Oncology Erin Hofstatter Medical Oncology Nina Horowitz Surgical Oncology Michael Hurwitz Medical Oncology Iris Isufi Hematology Benjamin Judson Otolaryngology Peter Koo Medical Oncology
Alfred Lee Hematology Arthur Levy Medical Oncology Miguel Materin Ophthalmology Daniel Morgensztern Medical Oncology Don Nguyen Pathology Abhijit Patel Therapeutic Radiology Nikolai Podoltsev Hematology Katie Politi Pathology Tara Sanft Medical Oncology Stacey Stein Medical Oncology Matthew Strout Hematology Narendra Wajapeyee Pathology Qin Yan Pathology |
Submissions
Please submit your recent publication and grant announcements to:
Renee Gaudette
Director, Public Affairs and Marketing
renee.gaudette@yale.edu
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