| Announcements
Susan Mayne Named C-E.A. Winslow Professor of Epidemiology I am delighted to congratulate Susan Mayne, PhD on her recent appointment by the Yale Corporation to the C.-E.A. Winslow Professor of Epidemiology in the School of Public Health. Susan is a wonderful colleague and friend and a close advisor to the Cancer Center in her role as Associate Director for Population Sciences. Her mentorship to members of the Cancer Prevention and Control Program over the past 20 years has resulted in countless cancer research projects. Susan is also P.I. of the Yale University - National Cancer Institute joint training program in cancer epidemiology and genetics, and she previously served on the Board of Scientific Counselors for the National Cancer Institute. In addition, Hongyu Zhao, PhD was named the Ira V. Hiscock Professor of Biostatistics and Tongzhang Zheng, DSc was appointed the Susan Dwight Bliss Professor of Environmental Health Sciences. Both Dr. Zhao and Dr. Zheng are members of Yale Cancer Center's Cancer Prevention and Control Research Program. Congratulations to both Dr. Zhao and Dr. Zheng on their well-deserved appointments.
Peter Schulam Appointed at Yale It is with great pleasure that we announce that Peter G. Schulam, MD, PhD, has been appointed chief of the Department of Urology at Yale-New Haven Hospital and chair of the department at Yale School of Medicine. Urology, previously a section within the Department of Surgery, has recently been elevated to departmental status. In addition, Dr. Schulam will lead the Prostate and Urologic Cancers Program at Smilow Cancer Hospital and will be a member of Yale Cancer Center's Executive Committee.
Dr. Schulam joins us from the Ronald Reagan Medical Center at the University of California at Los Angeles, where he was vice chair of urology, chief of the division of endourology and minimally invasive surgery, and director of both the kidney stone treatment center and the surgical living kidney donor program. Dr. Schulam was also a professor of urology and founder and co-director of the Center for Advanced Surgical and Interventional Technology.
Dr. Schulam has longstanding clinical interests in adrenal disorders; bladder, prostate, and kidney cancer; donor nephrectomy; and kidney stones and kidney reconstruction; and he is nationally known for his expertise in minimally invasive surgery and laparoscopic techniques. Clinical Trial Participation Improving I would like to recognize the hard work and effort everyone has made with respect to clinical trials at Yale Cancer Center over the last year. We opened 65 new clinical trials for our patients in the 2011 calendar year and 32% more patients were on a clinical trial for their care than in 2010.
While the total number of patients on a clinical trial in 2011 was 315, the rate over the last 6 months was almost 400 per year. We expect to see continued acceleration in our clinical trial numbers as new studies become available for our patients and as we incorporate our physician and research colleagues from the former MOH group. |
Notables Valentina Greco, PhD, Assistant Professor of Genetics, is the recipient of a 2012 Research Scholar Grant from the American Cancer Society to support her projectStem Cell Deregulation During Tumor Regression. She will receive $720,000 per year for four years to study and understand stem cell dynamics during tumor regression using a squamous cell carcinoma as a model system. Leslie Blatt, APRN, was awarded the 2011 Safe Passage Award for Outstanding Clinical Care from the Connecticut Coalition to Improve End-of-Life Care at their annual meeting. The award is presented to a clinician in recognition of outstanding clinical contributions to the field of end-of-life care. Janet Brandsma, PhD, Associate Professor of Comparative Medicine, and Malini Harigopal, MD, Assistant Professor of Pathology, received a $50,000 grant from the American Society of Cytology Foundation to study HPV16 DNA Methylation Frequency for the Improved Triage of ASCUS.
Kadisha Recalde joined Yale Cancer Center as an administrative assistant in the Business Office. Kadisha will be supporting Business Office functions, administration, and the faculty of the Smilow Care Centers.
Jeremy Rubenstein was hired at Yale Cancer Center as a financial assistant in the Business Office supporting the needs related to the CCSG, CTO, and Smilow among other activities.
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In Memoriam: Dr. Mel Goldstein
 Dr. Mel Goldstein, a longtime patient and wonderful supporter of Yale Cancer Center, passed away on Wednesday, January 18 at the age of 66. Dr. Mel and his wife Arlene hosted Cancer Survivors Day at Yale for the last 12 years. Dr. Mel's strength and spirit inspired countless patients in Connecticut over the years.
Dr. Mel was diagnosed with multiple myeloma 16 years ago and worked tirelessly with his care team to find new clinical trials and therapies. With the help of Dr. Dennis Cooper and Dr. Vincent DeVita, he was one of the first patients in the country to use thalidomide in 1998. He continued to research and seek out the newest and best possible treatments for his disease.
The staff and members of Yale Cancer Center and Smilow Cancer Hospital will miss Dr. Mel's smiling face and amazing positive attitude. Our thoughts are with Arlene and their daughters and grandson.
Dr. Mel's funeral will be held at 10:30 AM today at the Robert E. Shure funeral home on George Street in New Haven. |
Employee Profile: Maura Harrigan The Employee Profile recognizes the diverse contributions made by Yale Cancer Center and Smilow Cancer Hospital staff have to meet our patient care, research, education, and outreach goals. The staff profiled are examples of the great work being done here, and the dedication and values we possess. To suggest someone to be profiled, please contact Emily Fenton.
 Once patients have completed treatment for their cancer diagnosis they are often left with the question, "What's next?" That is where Maura Harrigan, MS, RD, CSO, registered dietitian for the Adult Survivorship Clinic at Yale Cancer Center, comes in. She meets with patients upon completion of their treatment and helps devise a plan for moving forward with their wellness. Maura is also a Research Associate at the Yale School of Public Health where she is currently serving as a Project Director for the Lifestyle, Exercise and Nutrition (LEAN) Study. Melinda Irwin, PhD, MPH, is the Principal Investigator for the LEAN Study, which is funded by the American Institute for Cancer Research. The study is for women that have been treated for breast cancer, and will examine if a dietary-induced weight loss program and moderate-intensity exercise leads to weight loss and improves serum markers associated with breast cancer. "We refer eligible and interested patients to the LEAN Study through the Survivorship Clinic. Being able to refer and encourage survivors to participate in research studies is a valuable resource of the Clinic," Maura said. "Cancer survivors have fought hard to get well, and now they want the tools to stay well." Maura also addresses late effects and long term effects of treatment with survivors such as increased risk for cardiovascular disease, osteoporosis, and type 2 diabetes mellitus. Dr. Irwin commented, "Maura understands the importance of clinical trials in moving the field forward and how to translate the most current scientific evidence on nutrition and cancer to the patients and the community. She possesses an innate ability to motivate individuals to change their lifestyles for the better. I feel so fortunate to be able to work with and learn from Maura on a daily basis."
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Funding Opportunities Samuel Waxman Cancer Research Foundation Grants Applications are being accepted for the 2012 Grants from the Samuel Waxman Cancer Research Foundation. Yale Cancer Center can send one application for review. If interested, please send a copy of your CV and a two-page description of your proposed project by email to Jan Zulkeski in Dr. Daniel DiMaio's office by 5:00 PM on Friday, February 24. Learn More >> PCF-Honorable A. David Mazzone Special Challenge Award Research Program 2012 Proposals must be from teams capable of providing unique scientific expertise to the solution of a significant problem in prostate cancer research. A team may be assembled from one institution, or several institutions, from across the globe. These awards focus on funding Treatment Sciences: Investigations of new ideas in man or laboratory support of a high impact clinical investigation.
Treatment Sciences research with a high probability of near-term patient benefit is required in the following topic areas: 1) Translational research in metabolism/adiposity/nutrition/survivorship 2) Molecular imaging in both primary and metastatic disease
3) Co-targeting tumor microenvironment 4) First-in-field research on new targets in metastatic disease systemic treatment 5) Mechanisms of resistance to new treatments for advanced prostate cancer 6) Diagnostics and biomarkers that differentiate indolent from metastatic prostate cancer Application Deadline: March 16, 2012 Learn More >> The Lymphoma Research Foundation (LRF) Grants New research grants for 2012 are available for the following lymphoma subtypes: Follicular Lymphoma Learn More >> Diffuse Large B-Cell Lymphoma Learn More >> CLL/SLL Learn More >> Application Deadline: February 13, 2012 |
Recent Publications Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma. Modi BG, Neustadter J, Binda E, Lewis J, Filler RB, Roberts SJ, Kwong BY, Reddy S, Overton JD, Galan A, Tigelaar R, Cai L, Fu P, Shlomchik M, Kaplan DH, Hayday A, Girardi M.
Science. 2012 Jan 6;335(6064):104-8.
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Indoor tanning and risk of early-onset basal cell carcinoma. Ferrucci LM, Cartmel B, Molinaro AM, Leffell DJ, Bale AE, Mayne ST.
J Am Acad Dermatol. 2011 Dec 8.
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Host Phenotype Characteristics and MC1R in Relation to Early-Onset Basal Cell Carcinoma. Ferrucci LM, Cartmel B, Molinaro AM, Gordon PB, Leffell DJ, Bale AE, Mayne ST.
J Invest Dermatol. 2011 Dec 8.
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Myxoid leiomyosarcoma of the uterus.
Burch DM, Tavassoli FA.
Histopathology. 2011 Dec;59(6):1144-55.
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Insular thyroid cancer: A population-level analysis of patient characteristics and predictors of survival. Kazaure HS, Roman SA, Sosa JA.
Cancer. 2012 Jan 17.
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ACR Appropriateness Criteria(®) Ductal Carcinoma in Situ. Moran MS, Bai HX, Harris EE, Arthur DW, Bailey L, Bellon JR, Carey L, Goyal S, Halyard MY, Horst KC, Macdonald SM, Haffty BG.
Breast J. 2012 Jan;18(1):8-15.
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Clinical utility of vandetanib in the treatment of patients with advanced medullary thyroid cancer. Deshpande H, Marler V, Sosa JA.
Onco Targets Ther. 2011;4:209-15.
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Radiosurgical dose selection for brain metastasis. Yu JB, Schulder M, Knisely J.
Prog Neurol Surg. 2012;25:139-47.
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Geographical information systems: applications and limitations in oncology research.
Aneja S, Gross CP, Soulos PR, Yu JB.
Oncology (Williston Park). 2011 Nov 15;25(12):1221-5.
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Employment experience of cancer survivors 2 years post-diagnosis in the Study of Cancer Survivors-I. Yu M, Ferrucci LM, McCorkle R, Ercolano E, Smith T, Stein KD, Cartmel B.
J Cancer Surviv. 2012 Jan 5.
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Prominent CD56 expression by damaged and regenerating muscle fibers in the skin. McKay K, McNiff J, Subtil A.
J Cutan Pathol. 2011 Dec 29.
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The melanoma 'epidemic': lessons from prostate cancer. Glusac EJ.
J Cutan Pathol. 2012 Jan;39(1):17-20.
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P75 Nerve Growth Factor Receptor as a Useful Marker to Distinguish Spindle Cell Melanoma From Other Spindle Cell Neoplasms of Sun-Damaged Skin. Sigal AC, Keenan M, Lazova R.
Am J Dermatopathol. 2011 Dec 29.
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Diminished number or complete loss of myoepithelial cells associated with metaplastic and neoplastic apocrine lesions of the breast. Tramm T, Kim JY, Tavassoli FA.
Am J Surg Pathol. 2011 Feb;35(2):202-11.
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| Countdown to the CCSG Submission 249 days until our CCSG
grant is due on
September 25, 2012.
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Inside
yalecancercenter.org Research in Progress Video presentations from Yale Cancer Center faculty on current research projects are now available online.
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In the News Read recent articles featuring experts from Yale Cancer Center. Read More >> Subscribe to Yale Cancer Center Answers on iTunes Yale Cancer Center's weekly radio program on CT Public Radio is ranked number 2 in the world for cancer programs on iTunes. Subscribe to the show.
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Events
January 20; 1:00 PM Developmental Therapeutics Research Program Seminar SHM I-116 Development of New Therapies for Melanoma-Beyond Ipilimumab and Vemurafenib Harriet Kluger, MD Learn More >> (PDF)
January 22; 6:00 PM Yale Cancer Center Answers WNPR
Translational Research in Lung Cancer Peter Koo, PhD and Daniel Morgensztern, MD Learn More >> January 23; 3:30 PM Signal Transduction Research Program Seminar SHM I-116 Structure and Function of a Cerebral Cavernoma-Associated Protein, CCM3 Titus Boggon, PhD Learn More >> (PDF) January 24; 12:00PM
Yale Cancer Center Grand Rounds
55 Park Street
Racial and Ethnic Disparities in Breast Cancer Outcomes Andrew L. Salner, MD Learn More >> (PDF)
January 25; 7:00 AM Research in Progress Meeting
WWW 208 Systemic Management of Colon Cancer Robert Mayer, MD Learn More >> (PDF)
January 25; 11:00 AM Radiobiology and Radiotherapy Research Program Seminar SHM I-304 High-Throughput Screening Reveals Novel Small Molecules That are Selectively Cytotoxic to DNA Repair-Deficient Cell Elizabeth Peterson-Roth, PhD Learn More >> (PDF)
January 26; 9:00AM
Therapeutic Radiology Grand Rounds Smilow, Lower Level, Room E
The Negative Impact of Physician Self-Referral on Graduate Medical Education and Health Care Costs Mitchell Anscher, MD Learn More >> January 27; 1:00 PM Genetics and Genomics Research Program Seminar
SHM I-116 Cytogenomic and Molecular Findings in MDS and AML Peining Li, PhD Learn More >> (PDF)
January 29; 6:00PM
Yale Cancer Center Answers WNPR
Clinical Trials from the Inside Out Tesheia Johnson Learn More >>
January 31; 12:00 PM
Yale Cancer Center Grand Rounds
55 Park Street Breast Cancer: Beyond Molecular Classification Lajos Pusztai, MD, DPhil Learn More >> (PDF)
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New Faculty Recruits (May 2009 - Present) Alexander Au Plastic Surgery Anees Chagpar Surgical Oncology Sandy Chang Lab Medicine Anne Chiang Medical Oncology Lieping Chen Immunobiology Deborah Chirnomas Pediatric Oncology Joseph Contessa Therapeutic Radiology Shari Damast Therapeutic Radiology Suzanne Evans Therapeutic Radiology Leonard Farber Medical Oncology Bonnie Gould Rothberg Medical Oncology Valentina Greco Genetics Stephanie Halene Hematology Roy Herbst Medical Oncology Howard Hochster Medical Oncology Erin Hofstatter Medical Oncology Nina Horowitz Surgical Oncology Michael Hurwitz Medical Oncology Iris Isufi Hematology Benjamin Judson Otolaryngology Jennifer Kapo Geriatrics Peter Koo Medical Oncology Alfred Lee Hematology Arthur Levy Medical Oncology Miguel Materin Ophthalmology Daniel Morgensztern Medical Oncology Don Nguyen Pathology Abhijit Patel Therapeutic Radiology Nikolai Podoltsev Hematology Katie Politi Pathology Tara Sanft Medical Oncology Fatma Shebl Epidemiology Stacey Stein Medical Oncology Matthew Strout Hematology Narendra Wajapeyee Pathology Qin Yan Pathology |
Submissions Please submit your recent publication and grant announcements to: Renee Gaudette Director, Public Affairs and Marketing
renee.gaudette@yale.edu
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