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Shilpa Hattangadi MD

Assistant Professor of Pediatrics (Hematology / Oncology) and of Pathology; Assistant Professor, Pathology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and Physiology

Stem Cell Center, Yale

Pediatric Hematology & Oncology Program

Pathology

Pediatrics: Pediatric Hematology & Oncology


Research Interests

Terminal erythroid development; Hematopoiesis; Bone marrow failure; Red cell aplasia; Chromatin condensation; Nuclear protein export; Proteomics; Genomics; Transcriptional regulation; Histone modification; Post-translational modification of hematopoietic regulators  more...


Education

  • B.S., MIT, 1995
  • M.D., Duke University Medical Center, 1999

Selected Publications

  • 13. SM Hattangadi, S Martinez, HC Patterson, J Shi, KA Burke, AA Figueroa, S Venkatesan, J Wang, K Paulsen, D Gorlich, M Murata-Hori, and HF Lodish, “Histones to the cytosol: Exportin 7 is essential for normal terminal erythroid nuclear maturation”. Blood, 2014, in press. Epub 2014 Aug 4.
  • 7. Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, Heggers SK, Law TC, Vogin G, Brugnara C, Zhou Y, Ebert BL, Danial NN, Fleming MD, Ward DM, Campanella M, Dailey HA, Kaplan J, and BH Paw. “Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts.” Nature. 2012 Nov 22; 491(7425):608-12. Epub 2012 Nov 7. PMID: 23135403
  • Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, J. King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, Freedman ML, Kingsley PD, Palis J,. Hattangadi SM, Lodish HF, Ward DM, Kaplan J, Maeda T, Ponka P, and BH Paw (2013). “Snx3 regulates recycling of the transferrin receptor and iron assimilation.” Cell Metabolism. 2013 Mar 5; 17(3):343-52. Epub 2013 Feb 14. PMID: 23416069

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