Shilpa Hattangadi MD

Assistant Professor of Pediatrics (Hematology / Oncology) and of Pathology; Assistant Professor, Pathology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and Physiology

Stem Cell Center, Yale

Pediatric Hematology & Oncology Program

Pathology: ExPath

Pediatrics: Pediatric Hematology & Oncology

Research Interests

Terminal erythroid development, hematopoiesis; Bone marrow failure; Red cell aplasia; Chromatin condensation; Nuclear protein export; Proteomics; Genomics; transcriptional regulation; Histone modification; Post-transcriptional modification of hematopoietic regulators  more...


  • B.S., MIT, 1995
  • M.D., Duke University Medical Center, 1999

Selected Publications

  • Chen C, Garcia-Santos D, Ishikawa Y, Seguin A, Li L, Fegan KH, Hildick-Smith GJ, Shah DI, Cooney JD, Chen W, J. King MJ, Yien YY, Schultz IJ, Anderson H, Dalton AJ, Freedman ML, Kingsley PD, Palis J,. Hattangadi SM, Lodish HF, Ward DM, Kaplan J, Maeda T, Ponka P, and BH Paw (2013). “Snx3 regulates recycling of the transferrin receptor and iron assimilation.” Cell Metabolism. (in press)
  • Hattangadi SM, Wong P, Zhang L, Flygare J, and HF Lodish (2011). From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins and RNAs (review). Blood. 2011 Dec 8; 118(24):6258-68. Epub 2011 Oct 12.
  • Wong P*, Hattangadi SM*, Cheng AW, Frampton GW, Young RA, and HF Lodish (2011) Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes. Blood. 2011 Oct 20; 118(16):e128-38. Epub 2011 Aug 22. *co-first authors



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