Alfred L. M. Bothwell PhD

Professor of Immunobiology; Director of Graduate Studies

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology

Program for Biomedical Ethics

Cancer Immunology

Vascular Biology and Therapeutics Program

Immunobiology: HTI

Skin Diseases Research Center, Yale

Diabetes Research Center

Immunology and Immunotherapy

Research Interests

Human T cell recognition; Inflammation and cancer; Type 1 diabetes; Function of PPARs  more...


  • BA, Washington University, 1971
  • Ph.D., Yale University, 1975

Selected Publications

  • Tobiasova, Z., Zhang, L., Yi, T., Qin, L., Kulkarni, S., Rodriguez, F., Choi, J.-M., Tellides, G., Pober, J.S., Kawikova, I. and Bothwell, A.L.M. (2011). PPAR? agonists prevent in vivo remodeling of human artery induced by alloreactive T cells. Circulation 124:196-205.
  • Chae, W.-J., Gibson, T.F., Zelterman, D., Hao, L., Henegariu, O. and Bothwell, A.L.M. (2010). Ablation of IL17A abrogates progression of spontaneous intestinal tumorigenesis. Proc. Natl. Acad. Sci. USA 107:5540-5544. PMC 2851824.
  • Lepus, C.M., Gibson, T., Kawikova, I., Gerber, S.A., Kirlikes-Smith, N., Szczepanik, M., Bothwell, A.L.M., Pober, J.S. and Harding, M.J. (2009). Characterization of human fetal liver, umbilical cord blood, and adult hematopoietic stem cell engraftment in C.B.17-scid/bg, Balb/c-Rag2-/-?c-/- and NOD-scid/?c-/- immunodeficient mice. Human Immunol., in press. PMID: 19524633.



Latest News


Edit Profile