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Program Members

Co-Leaders

Pusztai, Lajos

Clinical Interests: breast cancer; cancer genetics.

  • Appt: (203) 200-2328
     

Members

Bale, Allen Everett

Research Interests: Molecular Mechanisms of Cancer; Predisposition and Developmental Defects; DNA Diagnostics; Birth Defects; Cancer; Fanconi; Genetics; Hedgehog; Multiple Endocrine Neoplasia; Patched; Skin Cancer; Tumor Suppressor

    Baserga, Susan J

    Research Interests: Ribosome biogenesis; RRNA processing; U3 RNP structure and function; RNA helicases; Polymerase I transcription and processing

      Blair, Lauren Paige

      Research Interests: cancer; epigenetics; RNA processing; histone demethylation; post-translational modification; mass spectrometry

      • Office: (203) 785-6496

      Bosenberg, Marcus W.

      Research Interests: Melanocytic neoplasms; Soft tissue tumors; Cutaneous lymphoma; Genodermatoses

      • Office: (203) 737-3484
      • Appt: (203) 785-4094

      Braddock, Demetrios

      Research Interests: Structural biology; Hematopathology; Genitourinary Pathology

      • Office: (203) 737-1278

      Carling, Tobias

      Research Interests: Improved outcomes in minimally invasive endocrine surgery; Molecular genetics of endocrine tumors of the thyroid, parathyroid, adrenal (hyperaldosteronism, hypercortisolism, adrenal cancer, pheochromocytoma) and endocrine pancreas; Familial endocrine tumor susceptibility syndromes; Regulation of calcium homeostasis

      • Appt: (203) 737-2036

      Carrasco, Nancy

      • Office: (203) 785-4117

      Cooley, Lynn

      Research Interests: Molecular Genetics of Drosophila Oogenesis; Actin Cytoskeleton Regulation; Drosophila; Oogenesis; Ring Canal; Ovarian Muscle Function

      • Office: (203) 785-5067
      • Lab: (203) 785-2675

      Costa, Jose

      Research Interests: Oncology; Carcinogenesis; Tumor development and progression; Advanced diagnostics; Molecular diagnostics; Diagnosed genetic alterations in tumors; Cancer risk detection by mutational load distribution analysis

      • Office: (203) 785-5803

      Garen, Alan

      Research Interests: Development; Genetics; Medical Sciences; Molecular Biology

        Giraldez, Antonio J.

        Research Interests: Developmental Biology; Non-coding RNAs, Post-transcriptional regulation; microRNAs; Gene regulatory networks; Systems Biology; Zebrafish

        • Office: (203) 785-5423

        Gunel, Murat

        Research Interests: Molecular genetics and biology of brain aneurysms and cavernous malformations; Molecular genetics of brain development

        • Office: (203) 737-2096
        • Appt: (203) 737-2096

        Halaban, Ruth

        Research Interests: Genes controlling differentiation, proliferation, malignant transformation of melanocytes; Growth factors and receptor kinases; Signal transduction; Epigenetic modification and gene expression; Markers for melanoma, Next-Generation sequencing, mutations

        • Office: (203) 785-4352

        Halene, Stephanie

        Research Interests: Hematopoiesis; Myeloid differentiation; Leukemia; Myelodysplasia

        • Appt: (203) 200-4363

        Hatzis, Christos

        Research Interests: Personalized medicine; Molecular diagnostics; Cancer heterogeneity; Next generation sequencing; Diagnostic study design

          Hofstatter, Erin Wysong

          • Appt: (203) 200-2328

          Hoh, Josephine

          Research Interests: Interactions among genes; Environmental exposures

          • Office: (203) 785-2738
          • Lab: (203) 737-6007

          Ivanova, Natalia B.

          Research Interests: Embryonic and somatic stem cells; Vertebrate development; Functional genomics; Systems biology

            Katz, Samuel G.

            • Office: (203) 785-2757

            Khan, Sajid A

            Research Interests: Cancer; metastasis; oligometastasis; microRNA; gene expression profiling; microsatellite instability; clinical outcomes; surgical resection; surgical palliation; liver metastasis; pancreas; gastric cancer; gastrointestinal stromal tumors (GIST); early onset colorectal cancer; sarcoma

            • Office: (203) 737-7915
            • Appt: (203) 337-8507

            Kidd, Kenneth Kay

            Research Interests: Complex Human Disorders; Neuropsychiatric Disorders; Human Population ; Genetics; Human Evolution

            • Office: (203) 785-2654
            • Lab: (203) 785-2653

            Kim, Tae Hoon

            Research Interests: Transcription Regulation; Transcription Elongation; Transcription Insulation; Functional Genomics; Cancer Genomics; Epigenomics

              Kluger, Yuval

              Research Interests: Signal processing and dimensional reduction of genome-wide data; Local and non-local genomic pattern recognition; Identification of cancer subclones with proliferation and invasion potential in heterogeneous cancer biopsies

              • Office: (203) 737-6262

              Konigsberg, William H

              Research Interests: Blood Coagulation; DNA Replication; Genetics; Proteins and Macromolecules

                Krause, Diane S

                Research Interests: Bone Marrow Transplantation; Stem Cells; Cell and Molecular Hematology; Leukemia

                • Office: (203) 737-1678

                Kupfer, Gary

                Research Interests: Genomic instability; Development of cancer; Genetic syndrome Fanconi anemia (FA); Viral protein enhancement of cancer therapeutics

                • Office: (203) 785-4640
                • Appt: (203) 785-4640

                Lazova, Rossitza

                Research Interests: Spitz nevi; Spitzoid melanocytic neoplasms; Malignant melanoma; Melanocytic nevi on special anatomic sites

                • Office: (203) 785-4094
                • Appt: (203) 785-4094

                Leffell, David J.

                Research Interests: Molecular biology of basal cell carcinoma, squamous cell carcinoma; Wound healing; Skin cancer epidemiology

                • Appt: (203) 785-3466

                Lengyel, Peter

                Research Interests: p200 family proteins; mammalian differentiation; cell proliferation; interferons

                  Li, Peining

                  Research Interests: Cytogenetic and genomic analysis; Dissection of genetic mechanisms for growth regulation, mental development, and cancer progression

                  • Office: (203) 785-6317
                  • Appt: (203) 785-6317

                  Lifton, Richard P

                  Research Interests: Molecular genetics of common human diseases

                    Lin, Haifan

                    Research Interests: Stem cell RNA-mediated epigenetic programming, post-transcriptional regulation

                    • Office: (203) 785-6239
                    • Lab: (203) 785-6215

                    Lu, Jun

                    Research Interests: Non-coding RNAs in blood stem cell differentiation and malignancies; MicroRNA-mediated control of embryonic stem cell fates; MicroRNA mechanisms

                    • Office: (203) 737-3426

                    Mane, Shrikant M.

                    • Office: (203) 737-3104
                    • Lab: (203) 737-3058

                    Materin, Miguel A

                    Research Interests: Role of cytogenetics in ocular oncology for diagnosis and prognosis; Improving diagnostic and treatment methods for eye tumors

                    • Appt: (203) 200-3937

                    McGrath, James Michael

                    Research Interests: Developmental Genetics; Genetic Imprinting; Embryogenesis; Spermatogenesis

                    • Office: (203) 785-2686
                    • Appt: (203) 785-2660

                    Noonan, James

                    Research Interests: Human Evolution; Evolutionary Dynamics of Gene Regulation; Synthetic Biology; Applications of Ultra-High Throughput Sequencing Technologies; Comparative and Functional Genomics in Vertebrates

                      Pillai, Manoj M

                      • Office: (203) 737-6403
                      • Lab: (203) 737-6990

                      Prasad, Manju

                      Research Interests: Endocrine, Head & Neck Pathology; Genotype-phenotype correlation in tumors; Protein expression and biomarkers in tumor tissues, and their diagnostic & prognostic relevance

                      • Office: (203) 785-4862

                      Pusztai, Lajos

                      Research Interests: Breast cancer; Translational cancer research; Developing pharmacogenomic markers of response to breast cancer therapy and identifying methods to select the optimal treatment for each patient

                      • Appt: (203) 200-2328

                      Schwartz, Peter E

                      Research Interests: Ovarian Cancer; Uterine; Vaginal; Cervical and vulvar cancer; Screening for ovarian cancer

                      • Office: (203) 785-4014
                      • Appt: (203) 785-4014

                      Seli, Emre U

                      Research Interests: Translational regulation of gene expression during oocyte end early embryo development; Assessment of embryo viability in assisted reproductive technologies; Pathogenesis of endomentriosis.

                      • Office: (203) 785-7873
                      • Appt: (203) 785-4708

                      Shadel, Gerald S

                      Research Interests: Mitochondria; Mitochondrial Genetics and Biogenesis; Mitochondrial Dysfunction in Human Disease and Aging; Mechanisms of mtDNA Transcription and Mitochondrial Translation; Signaling Pathways that Sense and Control Mitochondrial Function; Cancer; Immune System Signaling

                      • Office: (203) 785-2475

                      Sklar, Jeffrey L.

                      Research Interests: Molecular biology of human disease, especially cancer; Molecular biologic methods of disease diagnosis; Cancer-related genes and their functions in neoplasia and normal cellular physiology; Chromosomal structure and chromosomal abnormalities in genetic and neoplastic disorders; Immunogenetics

                      • Office: (203) 785-6836

                      Strout, Matthew

                      Research Interests: Cancer genetics; Lymphomagenesis; Leukemogenesis; Immune diversification; Epigenetics; Tissue banking; Targeted therapy

                      • Office: (203) 785-7002
                      • Lab: (203) 737-6425
                      • Appt: (203) 200-4363

                      Taylor, Hugh S.

                      Research Interests: Endometriosis; Stem Cells; Embryo Implantation; Asherman's Syndrome; Menopause; Uterine Development; Endorcrine Disruption; Developmental Programming

                      • Office: (203) 785-4001
                      • Appt: (203) 785-4708

                      Udelsman, Robert

                      Research Interests: Minimally invasive surgery; Including techniques for minimizing the trauma of surgery; Endocrine surgery; Endocrine oncology

                      • Office: (203) 785-2697
                      • Appt: (203) 785-2697

                      Weissman, Sherman Morton

                      Research Interests: Globin and Histocompatibility Gene Structure and Function; Genome wide mapping of gene activity and chromosome structure in man; Transcription Factors; Lymphocyte and myeloid Transcription Networks; Stem Cells; Cell Senescence; Methods for Molecular Genetics

                      • Office: (203) 737-2281

                      Xiao, Andrew Zhuo

                      Research Interests: Chromatin biology; Histone variants; Modifications and chromatin remodeling complexes; Cellular reprogramming (iPS) and stem cell biology; Mammalian neural crest cell; Mammalian DNA damage response

                      • Office: (203) 737-3650
                      • Lab: (203) 785-5111

                      Xu, Mina LuQing

                      Research Interests: Peripheral T-cell lymphoma, NOS; Classical hodgkin lymphoma; EBV-related lymphoproliferative disorders; Hemophagocytic lymphohistiocytosis; Hematopoietic stem cell niche

                      • Office: (203) 737-6135

                      Xu, Tian

                      Research Interests: Genetic methodology; Cancer biology; Food and metabolism; Developmental mechanisms

                        Yan, Qin

                        Research Interests: Epigenetics; Gene regulation; Cancer biology; Stem cell biology

                        • Office: (203) 785-6672

                        Zhao, Hongyu

                        Research Interests: Statistical genomics; Computational biology; Genetic epidemiology; Genome wide association studies; Complex diseases; Risk prediction; High dimensional data; Dimension reduction; Network models; Graphical models; Bioinformatics; Next generation sequencing analysis; Cancer genomics; Epigenetics; Herbal medicine; Cicrobiome; Proteomics

                        • Office: (203) 785-3613