James Michael McGrath MD

Research Scientist in Comparative Medicine, in Genetics and in Pediatrics

Departments & Organizations

Yale Medical Group

Office of Student ResearchCancer Genetics & GenomicsComparative MedicinePediatrics: Pediatric Specialty Center | Genetics: Genetics Consultation ServiceCancer Genetics

Research Interests

Developmental Genetics; Genetic Imprinting; Embryogenesis; Spermatogenesis more...


  • B.A., Temple University, 1973
  • M.A., Temple University, 1976
  • Ph.D., Temple University, 1980
  • M.D., Temple University, 1986

Selected Publications

  • Lin ZP, Zhu YL, Johnson DR, Rice KP, Nottoli T, Hains BC, McGrath J, Waxman SG, Sartorelli AC (2008) Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response. Mol Pharmacol. 73(1):243-51.
  • Shaikh TH, O'Connor RJ, Pierpont ME, McGrath J, Hacker AM, Nimmakayalu M, Geiger E, Emanuel BS, Saitta SC (2007) Low copy repeats mediate distal chromosome 22q11.2 deletions: sequence analysis predicts breakpoint mechanisms. Genome Res. 17(4):482-91.
  • Hallaq H, Pinter E, Enciso J, McGrath J, Zeiss C, Brueckner M, Madri J, Jacobs HC, Wilson CM, Vasavada H, Jiang X, Bogue CW (2004) A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels. Development. 131(20):5197-209.



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