James Noonan PhD

Associate Professor of Genetics and of Ecology and Evolutionary Biology; Member, Kavli Institute for Neuroscience

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Computational Biology and Bioinformatics | Molecular Cell Biology, Genetics and Development

Stem Cell Center, Yale: Stem Cell Genetics

Cancer Genetics & Genomics

Animal Organogenesis

Kavli Institute for Neuroscience

Genetics: Noonan Lab

Research Interests

Human Evolution; Evolutionary Dynamics of Gene Regulation; Synthetic Biology; Applications of Ultra-High Throughput Sequencing Technologies; Comparative and Functional Genomics in Vertebrates more...


  • B.S., State University of New York at Binghamton, 1997
  • Ph.D., Stanford University, 2004

Selected Publications

  • Cotney J, Leng J, Yin J, Reilly SK, DeMare LE, Emera D, Ayoub AE, Rakic P, Noonan JP. (2013). The evolution of lineage-specific regulatory activities in the human embryonic limb. Cell 154:185-196.
  • DeMare LE, Leng J, Cotney J, Reilly SK, Yin J, Sarro R, Noonan JP. The genomic landscape of cohesin-associated chromatin interactions. Genome Res., epub May 23 2013.
  • Cotney J, Leng J, Oh S, DeMare LE, Reilly SK, Gerstein MB, Noonan JP. (2012). Chromatin state signatures associated with tissue-specific gene expression and enhancer activity in the embryonic limb. Genome Res. 22:1069-80.



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