Joann Balazs Sweasy PhD
Professor of Therapeutic Radiology and of Genetics; Vice-Chair for Basic Research
Departments & Organizations
Biological and Biomedical Sciences (BBS): Microbiology: Molecular Genetics | Molecular Cell Biology, Genetics and Development
Radiobiology & Radiotherapy Research
Therapeutic Radiology: Radiobiology
Genetics
Radiobiology and Radiotherapy
Research Interests
Genome Stability; Mutagenesis; DNA Replication; DNA Repair; Carcinogenesis more...
Education
- B.A., Beaver College, Glenside, PA, 1980
- Ph.D., Rutgers University, 1989
Selected Publications
- Stachelek GC, Dalal S, Donigan KA, Campisi Hegan D, Sweasy JB, Glazer PM. (2010) Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation. Cancer Res.70:409-17
- Kidane D, Jonason AS, Gorton TS, Mihaylov I, Pan J, Keeney S, de Rooij DG, Ashley T, Keh A, Liu Y, Banerjee U, Zelterman D, Sweasy JB. (2010) DNA polymerase beta is critical for mouse meiotic synapsis. EMBO J. 29:410-23
- Murphy DL, Jaeger J, Sweasy JB. (2011) A triad interaction in the fingers subdomain of DNA polymerase beta controls polymerase activity. J Am Chem Soc. 133:6279-87.
