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Program Members

Co-Leaders

Karen Anderson

Professor of Pharmacology and of Molecular Biophysics and Biochemistry
Co-Director Therapeutics/Chemotherapy Program

  • Office:(203) 785-4526
  • Lab:(203) 737-1527

Roy Herbst

Ensign Professor of Medicine (Medical Oncology) and Professor of Pharmacology
Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven
Associate Director for Translational Research, Yale Cancer Center
Clinical Research Program Leader, Thoracic Oncology Program, Yale Cancer Center

Clinical Interests:Lung cancer; Thoracic Oncology; Personalized Cancer Medicine; Clinical Trials for Lung cancer; Tumor profiling; Tumor biomakers

  • Office:(203) 785-6879
  • Appt:(203) 200-5864

Members

Maysa Abu-Khalaf

Associate Professor of Medicine (Medical Oncology) and of Obstetrics, Gynecology, and Reproductive Sciences

Research Interests:Clinical trials evaluating novel agents for the treatment of breast, ovarian and endometrial cancers; PI3K-mTOR inhibitors; HER-2 targeted therapies; angiogenesis

  • Office:(203) 737-8309
  • Appt:(203) 200-2328

Joachim Baehring

Associate Professor of Neurology, of Medicine (Medical Oncology) and of Neurosurgery
Clinical Program Leader, Brain Tumor Program, Smilow Cancer Hospital

Research Interests:Molecular markers of cancer; Nervous system lymphoma

  • Appt:(203) 785-7284

Ronald Breaker

Henry Ford II Professor of Molecular, Cellular, and Developmental Biology
Investigator, Howard Hughes Medical Institute

Research Interests:non-coding RNA; riboswitches; ribozymes; catalytic DNA; RNA's role in evolution

  • Office:(203) 432-9389
  • Lab:(203) 432-6554

Charles Cha

Associate Professor of Surgery (Oncology and Gastrointestinal)

Research Interests:Development of robotic and laparoscopic approaches for benign and malignant conditions of the liver, pancreas and stomach; Effects of angiogenesis on gastrointestinal malignancy; Gene silencing techniques to knockdown proliferation of hepatocellular carcinoma in vitro and in vivo; Diagnostic and therapeutic utility of angiogenic inhibitors for treatment of solid tumors; Clinical outcomes in surgery for sarcoma, hepatobiliary, gastric and esophageal malignancy

  • Appt:(203) 785-2380

Herta Chao

Associate Professor of Medicine (Medical Oncology)

Research Interests:Prostate cancer; androgen deprivation therapy; cognitive function; lung cancer; phospho-inositol-3 kinase pathway as a drug target

    Yung-Chi Cheng

    Henry Bronson Professor of Pharmacology
    Chairman, Consortium for the Globalization of Chinese Medicine (CGCM)

    Research Interests:Cancer; Viral chemotherapy; Chinese herbs; Chinese medicine

    • Office:(203) 785-7118
    • Lab:(203) 785-7119

    Anne Chiang

    Assistant Professor of Medicine (Medical Oncology)

      Jennifer Choi

      Assistant Professor of Dermatology
      Director, Yale Oncodermatology Clinic

      Research Interests:Cutaneous side effects of chemotherapy and radiation; Melanoma treatment

      • Office:(203) 785-4092
      • Appt:(203) 789-1249

      Gina Chung

      Assistant Professor of Medicine (Medical Oncology)

      • Office:(203) 785-2876
      • Appt:(203) 200-2328

      Craig Crews

      Lewis B. Cullman Professor of Molecular, Cellular, and Developmental Biology and Professor of Chemistry and of Pharmacology
      Executive Director, Yale Molecular Discovery Center

      Research Interests:Limb regeneration; wound epidermis; blastema; natural product mode of action studies; angiogenesis; Wnt signaling; protein turnover; protein kinase regulation

      • Office:(203) 432-9364
      • Lab:(203) 432-6553

      Hari Deshpande

      Assistant Professor of Medicine (Medical Oncology) and of Surgery (Otolaryngology) and Assistant Clinical Professor of Nursing

      Research Interests:Clinical trials in head and neck cancer; sarcoma; Genitourinary (GU) cancer; thyroid and endocrine cancers

      • Office:(203) 737-1600
      • Appt:(203) 200-4822

      Vincent DeVita, Jr

      Amy and Joseph Perella Professor of Medicine (Medical Oncology) and Professor of Epidemiology (Chronic Diseases) and of Medicine (Medical Oncology)

      Research Interests:Drug Resistance; Hodgkin's Disease; Lymphomas; Molecular Technology; Primary Chemotherapy

      • Office:(203) 737-1010

      Joseph Eder

      Research Interests:Phase I clinical trials; Cancer pharmacology; Angiogenesis

      • Appt:(203) 200-4422

      Barbara Ehrlich

      Professor of Pharmacology and of Cellular and Molecular Physiology

      Research Interests:Intracellular calcium regulation

      • Office:(203) 737-1158
      • Lab:(203) 737-1158

      Jonathan Ellman

      Professor of Chemistry
      Pharmacology

      Research Interests:proteases, phosphatases, inhibitors, C-H functionalization, asymmetric amine synthesis

        Donald Engelman

        Eugene Higgins Professor of Molecular Biophysics and Biochemistry

        Research Interests:Helix Interactions; Lipid Bilayers; Membranes; Physical Biochemistry; Protein Folding; Proteins

          Tarek Fahmy

          Associate Professor of Biomedical Engineering

            Leonard Farber

            Clinical Professor of Medicine (Medical Oncology)

            • Office:(203) 785-4191
            • Appt:(203) 200-6622

            Scott Gettinger

            Associate Professor of Medicine (Medical Oncology)

            Research Interests:Clinical trial design; novel therapeutics; radiosensitizers; prognostic biomarkers

            • Appt:(203) 200-5864

            Ya Ha

            Associate Professor of Pharmacology

            Research Interests:Membrane protein; X-ray crystallography; Enzyme mechanism

            • Office:(203) 785-7530
            • Lab:(203) 785-7360

            Seth Herzon

            Associate Professor of Chemistry

              Howard Hochster

              Professor of Medicine (Medical Oncology)
              Associate Director for Clinical Sciences, Yale Cancer Center
              Clinical Program Leader, Gastrointestinal Cancers Program, Smilow Cancer Hospital
              Clinical Research Program Leader, Gastrointestinal Cancers Program, Yale Cancer Center

              Research Interests:clinical research; pharmacology; anti cancer drug development; early clinical trials in cancer

              • Appt:(203) 200-4422

              Michael Hodsdon

              Associate Professor of Laboratory Medicine and of Pharmacology
              Assoc. Director, Clinical Chemistry Laboratory

              Research Interests:Biochemistry; Biophysics; Breast Cancer; Clinical Chemistry; Drug Metabolism; Health and Medicine; Laboratory Practice or Procedure; Nuclear Magnetic Resonance; Pathobiology; Pharmacology; Spectroscopy; Structural Biology; Toxicology

              • Office:(203) 688-2, 2
              • Appt:(203) 688-2445

              Zhiwei Hu

              Research Scientist

              Research Interests:Cancer Immunotherapy; Photodynamic Therapy; Tumor Angiogenesis; Cancer Stem Cell; Tumor Immunology; Natural Killer Cells

              • Lab:(203) 737-4669

              Sven-Eric Jordt

              Associate Professor of Pharmacology

              Research Interests:Sense of touch and pain in humans and animals; Chemosensory processes in sensory neurons and their role in chemical environmental exposures; Neural sensitization in asthma; Hypersensitivity disorders

              • Office:(203) 785-2159
              • Lab:(203) 737-1560

              William Jorgensen

              Sterling Professor of Chemistry
              Director, Division of Physical Sciences & Engineering

                Michael Kinch

                Associate Research Scientist in and Lecturer in Molecular, Cellular, and Developmental Biology

                  Harriet Kluger

                  Associate Professor of Medicine (Medical Oncology)
                  Associate Director, Hematology/Oncology Fellowship Program

                  Research Interests:Prognostic and predictive markers in melanoma and renal cell carcinoma; development of new drugs for melanoma and renal cell carcinoma

                  • Appt:(203) 200-6622

                  Jaseok Koo

                  Associate Professor of Medicine (Medical Oncology)

                  Research Interests:Cancer prevention and therapy; Lung carcinogenesis; Epithelial cell biology; Personalized medicine; Molecular targets; Drug development; Transcription Factor CREB; Inflammation; Cytokines and chemokines and receptors; Biomarkers for early detection and therapy

                    Jill Lacy

                    Associate Professor of Medicine (Medical Oncology)

                    Research Interests:Clinical research in gastrointestinal malignancies, including gastroesphageal, pancreatic, and colorectal cancers, and brain tumors; Epstein-Barr virus-associated malignancies

                    • Appt:(203) 200-4422

                    Jia Li

                    Assistant Professor of Medicine (Medical Oncology)

                      Elias Lolis

                      Professor of Pharmacology
                      Director of Graduate Studies

                      Research Interests:Cancer; Inflammation; Infectious disease; macromolecular X-ray crystallography; Signaling pathways; Drug design; High throughput screening (HTPS)

                      • Office:(203) 785-6233
                      • Lab:(203) 737-1526

                      Thomas Lynch

                      Richard Sackler and Jonathan Sackler Professor of Medicine (Medical Oncology)
                      Director, Cancer Center

                      Research Interests:Lung cancer; EGFR; Targeted therapy; Personalized medicine

                      • Appt:(203) 200-5864

                      Scott Miller

                      Irenee du Pont Professor of Chemistry
                      Professor
                      Department Chair

                        Gil Mor

                        Professor of Obstetrics, Gynecology, and Reproductive Sciences
                        Division Director, Reporductive Sciences
                        Director Reproductive Immunology Unit and Discovery to Cure Program
                        Editor in Chief, AJRI

                        Research Interests:Immunology of Gynecologic tumors; Immunology of Implantation; Ovarian Cancer Stem Cells

                        • Office:(203) 785-6294
                        • Lab:(203) 737-1405

                        Daniel Morgensztern

                        Assistant Professor of Medicine (Medical Oncology)

                        Research Interests:Lung cancer; targeted therapy; molecular diagnosis; prognosis; supportive care; epidemiology; head and neck cancer

                        • Appt:(203) 200-5864

                        Peter Peduzzi

                        Professor of Public Health (Biostatistics)
                        Director, Yale Center for Analytical Sciences (YCAS)

                        Research Interests:Clinical trials; comparative effectiveness research; general statistical methods; variable selection

                          Andrew Phillips

                          Professor of Chemistry

                            Joseph Piepmeier

                            Nixdorff-German Professor of Neurosurgery
                            Vice Chair of Clinical Affairs, Neurosurgery
                            Section Chief, Neuro-Oncology
                            Director, Surgical Neuro-Oncology
                            Clinical Research Program Leader, Brain Tumor Program, Yale Cancer Center

                            Research Interests:neuro-oncology; acoustic neuroma; general neurosurgery; brain and spinal cord cancer; brachytherapy; stereotactic needle biopsy

                            • Appt:(203) 785-2791

                            Nikolai Podoltsev

                            Assistant Professor of Medicine (Hematology)
                            Associate Director of the Hematology/Oncology Fellowship Program

                            • Appt:(203) 200-4363

                            Lynne Regan

                            Professor of Molecular Biophysics and Biochemistry and of Chemistry

                            Research Interests:Mental retardation; protein-protein interactions; Fragile X Mental Retardation Protein (FMRP); protein-based nanomaterials

                              John Roberts

                              Director, Adult Sickle Cell Program at Yale-New Haven Hospital

                              Research Interests:Clinical trials; clinical trials design.

                                Michal Rose

                                Associate Professor of Medicine (Medical Oncology)
                                Director, VA Comprehensive Cancer Center
                                Chair, Data and Safety Monitoring Committee, Yale Cancer Center

                                • Office:(203) 937-3421

                                Thomas Rutherford

                                Professor of Obstetrics, Gynecology, and Reproductive Sciences
                                Section Chief, Gynecologic Oncology

                                Research Interests:Minimally invasive surgical techniques; Ovarian stem cell research; Micro-RNA; Novel biologic agents for treatment; Early detection of ovarian cancer

                                • Office:(203) 785-6301
                                • Appt:(203) 200-4176

                                W. Mark Saltzman

                                Goizueta Foundation Professor of Biomedical Engineering and Professor of Cellular and Molecular Physiology and of Chemical Engineering
                                Department Chair, Biomedical Engineering

                                Research Interests:Bio-compatible polymers, drug delivery systems

                                • Office:(203) 432-4262

                                Alan Sartorelli

                                Alfred Gilman Professor of Pharmacology

                                Research Interests:Cancer research; Drug development; Drug resistance

                                • Office:(203) 785-4533
                                • Lab:(203) 785-4534

                                Clarence Sasaki

                                Charles W. Ohse Professor of Surgery (Otolaryngology)

                                Research Interests:Laryngeal physiology, head and neck cancer

                                • Appt:(203) 785-2592

                                William Sessa

                                Alfred Gilman Professor of Pharmacology and Professor of Medicine (Cardiology)
                                Vice Chairman, Pharmacology
                                Director, Vascular Biology & Therapeutics Program

                                Research Interests:Vascular endothelium and inflammation; MiRNAs; Vascular development and angiogenesis; Lipid domains and signaling; Atherosclerosis

                                • Office:(203) 737-2291

                                David Spiegel

                                Associate Professor of Chemistry

                                Research Interests:Design of novel molecules that enhance the recognition of various pathogens, including viruses, by the human immune system

                                • Office:(203) 432-8697

                                Stacey Stein

                                Assistant Professor of Medicine (Medical Oncology)

                                • Appt:(203) 200-4422