Thomas James Lynch, MD

Richard Sackler and Jonathan Sackler Professor of Medicine (Medical Oncology)

Physician Biography

Thomas J. Lynch, Jr., MD began his tenure as Director of Yale Cancer Center and Physician-in-Chief of Smilow Cancer Hospital at Yale-New Haven on April 1, 2009. The Jonathan and Richard Sackler Professor of Medicine, Dr. Lynch is an expert in the treatment of lung cancer with a special interest in personalized medicine.


A member of the Board of Directors for Bristol-Myers Squibb Company, Dr. Lynch is internationally known for his leadership in the development of novel therapies for the treatment of lung cancer. Using the molecular profile of lung tumors, he and his research team have developed methods to predict a tumor’s response to targeted drugs based on confirmed mutations in the epidermal growth factor receptor gene. The resulting information enables oncologists to create treatment plans that more effectively target each patient’s specific tumor type. This kind of customized care, often referred to as personalized medicine, is a standard of practice at Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven.


Dr. Lynch is the Chair of the Board of Directors and a founding member of the nationally recognized Kenneth B. Schwartz Center, named after a former patient of his. Currently in 39 states and at over 320 different sites, the Schwartz Center Rounds are multidisciplinary rounds focused on the connection between patients and caregivers to promote compassionate care. The Rounds were brought to Yale Cancer Center in 2007 and continue under Dr. Lynch’s leadership.


At Yale Cancer Center, Dr. Lynch is also overseeing the creation of a new Cancer Biology Institute on Yale’s West Campus, directed by Dr. Joseph Schlessinger. The Institute will encourage collaborative research and will include the fields of cell signaling, cancer immunology, and drug development and target acquisition.


Prior to joining Yale, Dr. Lynch served as Professor of Medicine at Harvard Medical School and Chief of Hematology/Oncology at Massachusetts General Hospital (MGH) Cancer Center. Dr. Lynch received his undergraduate degree from Yale College in 1982 and his MD degree from Yale School of Medicine in 1986. He completed his internship and residency at MGH, and after serving a fellowship in medical oncology at the Dana-Farber Cancer Institute he joined the medical staff at the Massachusetts General Hospital in 1993.


Dr. Lynch is a member of the American Association for Cancer Research, the American Society of Clinical Oncology, and the International Association for the Study of Lung Cancer. He is on the editorial boards of the journal, Clinical Cancer Research, and the Journal of Clinical Oncology. Dr. Lynch has published over 100 original scientific papers and authored or co-authored over 90 review articles and book chapters.

Clinical Interests

  • Lung Neoplasms
  • Medical Oncology

Patient Care

Accepts new patients? Yes
Patient Type: Adult
Referrals: From patients or physicians

Patient Care Organizations

Medical Oncology

Yale Medical Group

Clinical Trials

Conditions Study Title
Unknown Sites An Investigation of Tumor-Derived Mutated DNA in the Blood and Urine as a Biomarker for Cancer Treatment Response
Lung Lung Cancer Mutation Consortium Protocol
Unknown Sites Tumor Molecular Profiling

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Contact Info

Thomas James Lynch, MD
Patient Care Location
Smilow Cancer Hospital at Yale-New HavenSmilow Cancer Hospital at Yale - New Haven
35 Park Street, Ste North Pavilion 4

New Haven, CT 06511
Mailing Address
PO Box 208028
333 Cedar Street, WWW 205

New Haven, CT 06520-8028