Thomas J. Rutherford MD, PhD

Professor of Obstetrics, Gynecology, and Reproductive Sciences

Research Interests

Minimally invasive surgical techniques; Ovarian stem cell research; Micro-RNA; Novel biologic agents for treatment; Early detection of ovarian cancer

Research Summary

Our goal is to understand how a cancer cell becomes chemo-resistant. We have isolated the cancer cells that demonstrate this resistance and are working a method to either reverse the chemo-resistance of another means to destroy these cells.

Selected Publications

  • Bellone S, Siegel ER, Cocco E, Cargnelutti M, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S, Santin AD. Overexpression of epithelial cell adhesion molecule in primary, metastatic, and recurrent/chemotherapy-resistant epithelial ovarian cancer: implications for epithelial cell adhesion molecule-specific immunotherapy. Int J Gynecol Cancer. 2009 Jul;19(5):860-6.
  • Ratner ES, Toy E, O'Malley DM, McAlpine J, Rutherford TJ, Azodi M, Higgins SA, Schwartz PE. Brain metastases in epithelial ovarian and primary peritoneal carcinoma.Int J Gynecol Cancer. 2009 Jul;19(5):856-9.

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