Zhe Jay Chen, PhD, FAAPM

Professor of Therapeutic Radiology; Smilow Chief Physicist; Director of Medical Physics Residency Program

Departments & Organizations

Therapeutic Radiology: Radiological Physics

Faculty Research

Yale Cancer Center: Radiobiology & Radiotherapy

Office of Cooperative Research


Dr. Zhe (Jay) Chen received his B.S. degree in theoretical physics from Fudan University in Shanghai, China in 1982. In the same year, he was selected by Nobel Laureate T.D. Lee's China-US Physics Scholarship program to pursue graduate study in physics in the United States. After receiving a Ph.D. degree in theoretical condensed matter physics from the City University of New York in 1989, he continued postdoctoral research in physics at Brown University from 1989 to 1992. Driven by the desire to put his training in theoretical physics to more practical applications, he joined the Department of Radiation Oncology of the State University of New York (SUNY) at Stony Brook in 1992. He found the application of radiation physics and radiobiology in radiation therapy not only helpful to cancer patients but also intellectually stimulating and satisfying to a physicist. He became a clinical medical physicist and an assistant professor of research in the Health Science Center and SUNY School of Medicine at Stony Brook. In 1995, he joined the Department of Therapeutic Radiology at Yale-New Haven Hospital and Yale University School of Medicine and has stayed here since. In addition to providing clinical medical physics support in daily patient care, he has been actively involved in teaching physics of radiation therapy to radiation oncology and medical physics residents and in conducting original research towards better understanding and effective use of physics in radiation therapy. He has authored and/or coauthored over 85 peer-reviewed research articles, 14 book chapters and reviews, and over 150 published research abstracts. He has been a research investigator on 5 federal government supported research grants and was the principal investigator of a NIH R01 research grant investigating the effects of prostate edema on the treatment of early-stage prostate cancer using permanent interstitial brachytherapy.

Education & Training

PhD City University of New York (1989)
MPhil City University of New York (1985)
BS Fudan University (1982)
Postdoctoral fellow Brown University

Honors & Recognition

  • FellowAmerican Association of Physicists in Medicine (2012)

  • Master of Arts (Honorary)Yale University (2012)

  • NIH R01 Research Grant AwardNational Cancer Institute (2008)

  • Distinguished Service Award, Board of DirectorsAmerican Association of Physicists in Medicine (2008)

  • President (Service Award)Connecticut Area Medical Physics Society (2002)

Professional Service

  • American Association of Physicists in Medicine (AAPM) (2014) Chair of Task Group No. 267 - Biophysical models and tools for the planning and evaluation of selected brachytherapy modalities

  • American Society for Radiation Oncology (ASTRO) (2014) Member, Physics Core Curriculum Committee

  • American Association of Physicists in Medicine (AAPM) (2013) Member, Working Group on Brachytherapy Clinical Applications

  • International Journal of Radiation Oncology, Biology, Physics (2011 - 2014) Associate Senior Editor

  • American Association of Physicists in Medicine (AAPM) (2011) Member, Radiation Oncology Medical Physics Education Subcommittee

  • American Board of Radiology (ABR), Oral Examiner (2010 - 2015) Member

  • Italian Ministry of Health, Department of Research (2009 - 2012) Research Grant Review

  • US Army, Department of Defense (2009 - 2009) Research Grants of congressionally directed medical research programs (CDMRP)

  • American Association of Physicists in Medicine (2008 - 2014) Member, Imaging for Treatment Assessment Work Group

  • American Association of Physicists in Medicine (2006 - 2010) Member, Task Group No. 137 - AAPM Recommendations on dose prescription and reporting methods for permanent interstitial brachytherapy for prostate cancer.

  • American Society for Radiation Oncology (2006) Member

  • Medical Physics (2005) Guest Associate Editor & Reviewer

  • Connecticut Area Medical Physics Society (1996) Member

  • American Association of Physicists in Medicine (1993) Member

Edit this profile