James Noonan, PhD

Associate Professor of Genetics and of Ecology and Evolutionary Biology; Member, Kavli Institute for Neuroscience

Departments & Organizations

Animal Organogenesis

Cancer Genetics & Genomics

Genetics: Noonan Lab

Kavli Institute for Neuroscience

Office of Student Research

Stem Cell Center, Yale: Stem Cell Genetics

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Computational Biology and Bioinformatics: Computational Approaches to Functional and Integrative Genomics | Molecular Cell Biology, Genetics and Development: Genetics and Genomics


Dr. Noonan received his undergraduate degree in Biology and English Literature (Honors) from Binghamton University in upstate New York. After two years as a research technician at the New York Blood Center, he moved to the Department of Genetics, Stanford University, where he received his Ph.D. in 2004. With Dr. Richard Myers, Dr. Noonan used comparative genomics and de novo genomic sequencing to reconstruct the evolutionary history of the vertebrate protocadherin gene cluster, which encodes cell adhesion molecules required for brain development and synaptic specificity. Dr. Noonan did his postdoctoral work with Dr. Edward Rubin at the Lawrence Berkeley National Laboratory and the U.S. Department of Energy Joint Genome Institute. At LBNL, Dr. Noonan developed a metagenomic library approach in combination with massively parallel 454 pyrosequencing to recover and analyze genomic DNA from 40,000-year old cave bear and Neanderthal remains. As a postdoc Dr. Noonan also worked on methods to identify signatures of human-specific accelerated evolution in noncoding DNA. Dr. Noonan joined the Yale Genetics faculty in September 2007.

Education & Training

PhD Stanford University (2004)
BS State University of New York at Binghamton (1997)

Honors & Recognition

  • Mallinckrodt Foundation FellowshipEdward J. Mallinckrodt Foundation (2008)

Professional Service

  • Editorial Board Member Editorial Board Member, Genome Research (2007)

  • Member, Center for Academic Training and Research in Anthropogeny

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Contact Info

James Noonan, PhD
Mailing Address
Department of GeneticsPO Box 208005
333 Cedar Street

New Haven, CT 06520-8005

Noonan Lab