Recent Publications

Cao J, Yan Q.
Histone demethylases set the stage for cancer metastasis.
Sci Signal. 2013 Apr 30;6(273):pe15.

Kidd M, Gustafsson B, Modlin IM.
Gastric carcinoids (neuroendocrine neoplasms).
Gastroenterol Clin North Am. 2013 Jun;42(2):381-97.

Kwak M, Mu L, Lu Y, Chen JJ, Wu Y, Brower K, Fan R.
Erratum: single-cell protein secretomic signatures as potential correlates to tumor cell lineage evolution and cell-cell interaction.
Front Oncol. 2013 Apr 8;3:78.

Sayegh J, Cao J, Zou MR, Morales A, Blair LP, Norcia M, Hoyer D, Tackett AJ, Merkel JS, Yan Q.
Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1B (JARID1B) Histone Demethylase by a Sensitive High-throughput Screen.
J Biol Chem. 2013 Feb 13.

Metheetrairut C, Slack FJ.
MicroRNAs in the ionizing radiation response and in radiotherapy.
Curr Opin Genet Dev. 2013 Feb 27. 

Kim YJ, Greer CB, Cecchini KR, Harris LN, Tuck DP, Kim TH.
DAC inhibitors induce transcriptional repression of high copy number genes in breast cancer through elongation blockade.
Oncogene. 2013 Feb 25.

Sayegh J, Cao J, Zou MR, Morales A, Blair LP, Norcia M, Hoyer D, Tackett AJ, Merkel JS, Yan Q.
Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1B (JARID1B) Histone Demethylase by a Sensitive High-throughput Screen.
J Biol Chem. 2013 Feb 13.

Scholl UI, Lifton RP.
New insights into aldosterone-producing adenomas and hereditary aldosteronism: mutations in the K+ channel KCNJ5.
Curr Opin Nephrol Hypertens. 2013 Jan 10.

Zhao S, Choi M, Overton JD, Bellone S, Roque DM, Cocco E, Guzzo F, English DP, Varughese J, Gasparrini S, Bortolomai I, Buza N, Hui P, Abu-Khalaf M, Ravaggi A, Bignotti E, Bandiera E, Romani C, Todeschini P, Tassi R, Zanotti L, Carrara L, Pecorelli S, Silasi DA, Ratner E, Azodi M, Schwartz PE, Rutherford TJ, Stiegler AL, Mane S, Boggon TJ, Schlessinger J, Lifton RP, Santin AD.
Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma.
Proc Natl Acad Sci U S A. 2013 Jan 28.

Adams BD, Guo S, Bai H, Guo Y, Megyola CM, Cheng J, Heydari K, Xiao C, Reddy EP, Lu J.
An In Vivo Functional Screen Uncovers miR-150-Mediated Regulation of Hematopoietic Injury Response.
Cell Rep. 2012 Oct 17.

Brierley KL, Blouch E, Cogswell W, Homer JP, Pencarinha D, Stanislaw CL, Matloff ET.
Adverse events in cancer genetic testing: medical, ethical, legal, and financial implications.
Cancer J. 2012 Jul;18(4):303-9. 

Matloff ET
From the guest editor: cancer genetic counseling and testing: past, present, and future.
Cancer J. 2012 Jul;18(4):285-6

Cromer MK, Starker LF, Choi M, Udelsman R, Nelson-Williams C, Lifton RP, Carling T.
Identification of Somatic Mutations in Parathyroid Tumors Using Whole-Exome Sequencing.
J Clin Endocrinol Metab. 2012 Jun 27.

Bellone S, Roque D, Cocco E, Gasparrini S, Bortolomai I, Buza N, Abu-Khalaf M, Silasi DA, Ratner E, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S, Santin AD.
Downregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: implications for trastuzumab-based immunotherapy.
Br J Cancer. 2012 Apr 24;106(9):1543-50.

Hanna JA, Wimberly H, Kumar S, Slack F, Agarwal S, Rimm DL.
Quantitative analysis of microRNAs in tissue microarrays by in situ hybridization.
Biotechniques. 2012 Apr;52(4):235-45.

Lo SM, Choi M, Liu J, Jain D, Boot RG, Kallemeijn WW, Aerts JM, Pashankar F, Kupfer GM, Mane S, Lifton RP, Mistry PK.
Phenotypic diversity in type 1 Gaucher disease: discovering the genetic basis of Gaucher disease/hematological malignancy phenotype by individual genome analysis.
Blood. 2012 Apr 4.

Cao J and Yan
Q  Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer.
Front. Oncol. 2:26. doi: 10.3389/fonc.2012.00026 

Kundu ST, Nallur S, Paranjape T, Boeke M, Weidhaas JB, Slack FJ.
KRAS alleles: The LCS6 3'UTR variant and KRAS coding sequence mutations in the NCI-60 panel.
Cell Cycle. 2012 Jan 15;11(2).

Russ R, Slack FJ.
Cigarette-Smoke-Induced Dysregulation of MicroRNA Expression and Its Role in Lung Carcinogenesis
Pulm Med. 2012;2012:791234. Epub 2011 Dec 1.

Kasinski AL, Slack FJ.
MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy.
Nat Rev Cancer. 2011 Nov 24;11(12):849-64.

DA, Slack FJ.
MicroRNAs in Mutagenesis, Genomic Instability, and DNA Repair.
Semin Oncol. 2011 Dec;38(6):743-51

Weidhaas JB, Slack FJ.
KRAS rs61764370 in Epithelial Ovarian Cancer-Letter.
Clin Cancer Res. 2011 Oct 15;17(20):6600.

Babar IA Czochor J, Steinmetz A. Weidhaas JB. Glazer PM, Slack FJ.
Inhibition of hypoxia-induced miR-155 radiosensitizes hypoxic lung cancer cells.
Cancer Biol Ther. 2011 Nove 15;12(10)

Kluger, H.M., Hoyt, K., Bacchiocchi, A., Mayer, T., Kirsch, J., Kluger, Y., Sznol, M., Ariyan, S., Molinaro, A., Halaban, R.
Plasma markers for identifying patients with metastatic melanoma
(2011) Clinical Cancer Research, 17 (8), pp. 2417-2425.

Paranjape, T., Heneghan, H., Lindner, R., Keane, F.K., Hoffman, A., Hollestelle, A., Dorairaj, J., Geyda, K., Pelletier, C., Nallur, S., Martens, J.W.M., Hooning, M.J., Kerin, M., Zelterman, D., Zhu, Y., Tuck, D., Harris, L., Miller, N., Slack, F., Weidhaas, J.
A 3'-untranslated region KRAS variant and triple-negative breast cancer: A case-control and genetic analysis
(2011) The Lancet Oncology, 12 (4), pp. 377-386.

Godshalk, S.E., Paranjape, T., Nallur, S., Speed, W., Chan, E., Molinaro, A.M., Bacchiocchi, A., Hoyt, K., Tworkoski, K., Stern, D.F., Sznol, M., Ariyan, S., Lazova, R., Halaban, R., Kidd, K.K., Weidhaas, J.B., Slack, F.J.
A Variant in a MicroRNA complementary site in the 3′ UTR of the KIT oncogene increases risk of acral melanoma
(2011) Oncogene, 30 (13), pp. 1542-1550. Cited 1 time.

Starker, L.F., Delgado-Verdugo, A., Udelsman, R., Björklund, P., Carling, T.
Expression and somatic mutations of SDHAF2 (SDH5), a novel endocrine tumor suppressor gene in parathyroid tumors of primary hyperparathyroidism
(2010) Endocrine, 38 (3), pp. 397-401.