Richard A Flavell PhD, FRS

Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute; Department Chair, Immunobiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology

Office of Student ResearchStem Cell Center, Yale: Stem Cell Niche and Homing; Stem Cell Self-Renewal and Cell SymmetryCancer ImmunologyVascular Biology and Therapeutics ProgramImmunobiology: Lymphocyte Development; HTIPrincipal InvestigatorParasitology ProgramSkin Diseases Research Center, Yale | SPORE in Skin CancerFellowship Training | Diabetes Research CenterNIH T32 ProgramImmunology and Immunotherapy

Research Interests

Animal Models; Autoimmunity; Diabetes; Gene Expression; Gene Transfer; Genes; Immune System; Lyme Borreliosis Or Lyme Disease; Molecular Cellular Entities; Recombinant DNA; Transgenic Animals; Autoimmunity; Knockout Mice; Lyme Disease; T Cell Lineages; Tolerance; Transgenic Mice more...


  • Ph.D., Hull University, 1970

Selected Publications

  • Palm NW, de Zoete MR, Cullen TW, Barry NA, Stefanowski J, Hao L, Degnan PH, Hu J, Peter I, Zhang W, Ruggiero E, Cho JH, Goodman AL and Flavell RA: Immunoglobulin a coating identifies colitogenic bacteria in inflammatory bowel disease. Cell. 2014 Aug 28;158 (5) :1000-10. PMID: 25171403
  • Wlodarska M, Thaiss CA, Nowarski R, Henao-Mejia J, Zhang JP, Brown EM, Frankel G, Levy M, Katz MN, Philbrick WM, Elinav E, Finlay BB and Flavell RA: NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion. Cell. 2014 Feb 27;156 (5) :1045-59. PMID: 24581500
  • Rongvaux A, Willinger T, Martinek J, Strowig T, Gearty SV, Teichmann LL, Saito Y, Marches F, Halene S, Palucka AK, Manz MG and Flavell RA: Development and function of human innate immune cells in a humanized mouse model. Nat Biotechnol. 2014 Apr;32 (4) :364-72. Epub 2014 Mar 16. PMID: 24633240



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