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Patrick Sung DPhil, Ph.D.

Professor of Molecular Biophysics and Biochemistry and of Therapeutic Radiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology

Radiobiology & Radiotherapy

Molecular Biophysics and Biochemistry: DNA Replication and Repair | Sung Lab

Therapeutic Radiology/Radiation Oncology: Radiobiology

Radiobiology and Radiotherapy


Research Interests

Repair of DNA double-strand breaks; Repair by homologous recombination; Repair by DNA end-joining more...


Education

  • B.S., University of Liverpool, 1981
  • D.Phil., University of Oxford, 1985

Selected Publications

  • Dray E, Etchin J, Wiese C, Saro D, Williams GJ, Hammel M, Yu X, Galkin VE, Liu D, Tsai MS, Sy SM, Schild D, Egelman E, Chen J, Sung P.Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Nat Struct Mol Biol. 2010 Oct;17(10):1255-9.
  • Niu H, Chung WH, Zhu Z, Kwon Y, Zhao W, Chi P, Prakash R, Seong C, Liu D, Lu L, Ira G, Sung P.Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae. Nature. 2010 Sep 2;467(7311):108-11.
  • Longerich S, San Filippo J, Liu D, Sung P. FANCI binds branched DNA and is mono-ubiquitinated by UBE2T-FANCL. J Biol Chem. 2009 Jul 18.

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