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Developmental Therapeutics

Ronald R Breaker

Henry Ford II Prof Mol Cell & Dev Biology; Investigator, Howard Hughes Medical Institute

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology

Molecular, Cellular, and Developmental Biology

NHLBI Proteomics

Developmental Therapeutics

Center for RNA Science and Medicine, Yale

Molecular Biophysics and Biochemistry: RNA Biology

Developmental Therapeutics


Research Interests

non-coding RNA; riboswitches; ribozymes; catalytic DNA; RNA and evolution; antibiotics development more...


Selected Publications

  • A. Roth, Z. Weinberg, A. G. Chen, P. Kim, T. D. Ames, R. R. Breaker (2014) A Widespread Self-cleaving Ribozyme Class is Revealed by Bioinformatics. Nat. Chem. Biol. 10:56-60.
  • J. W. Nelson, N. Sudarsan, K. Furukawa, Z. Weinberg, J. X. Wang, R. R. Breaker (2013) Riboswitches in Eubacteria Sense the Second Messenger c-di-AMP. Nat. Chem. Biol. 9:834-839.
  • A. Roth, R. R. Breaker (2013) Integron attI Sites, Not Riboswitches, Associate with Antibiotic Resistance Genes. Cell 153:1417-1418.

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