Joseph Anthony Madri MD, PhD

Professor of Pathology; Director of Education

Departments & Organizations

Yale Medical Group

Office of Student ResearchStem Cell Center, Yale: Stem Cell Niche and HomingSignal TransductionVascular Biology and Therapeutics ProgramSkin Diseases Research Center, Yale | Pathology: Surgical Pathology; Madri LabNIH T32 Program

Research Interests

Connective tissue disorders; Cell-Matrix and Cell-Cell Interactions; Integrin-Mediated Signaling; Cardio-vascular and neuro-vascular development; Angiogenesis and Vascular Biology; inflammation; T-cell–Endothelial cell interactions more...


  • Ph.D., Indiana University School of Medicine, 1973
  • M.D., Indiana University School of Medicine, 1975

Selected Publications

  • Li, Q, Canosa S, Michaud, M., Flynn, K., Krauthammer, M., J.A. Madri. Modeling the Neurovascular Niche: Unbiased Transcriptome Analysis of the Murine Subventricular Zone in Response to Hypoxic Insult, PLOS One, In Press, 2013.
  • Flynn, K., Michaud, M., J.A. Madri. CD44 Deficiency Contributes to Enhanced Experimental Autoimmune Encephalomyelitis: A Role in Immune Cells and Vascular Cells 2 of the Blood Brain Barrier3, American Journal of Pathology, 182(4):1322-1336, 2013.
  • Flynn, K., Michaud, M., Canosa, S., J.A. Madri. CD44 Regulates Vascular Endothelial Barrier Integrity via a PECAM-1 Dependent Mechanism, Angiogenesis, 16:689-705, 2013.



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