2024
Pancreatic Cancer Surveillance and Survival of High-Risk Individuals
Blackford A, Canto M, Dbouk M, Hruban R, Katona B, Chak A, Brand R, Syngal S, Farrell J, Kastrinos F, Stoffel E, Rustgi A, Klein A, Kamel I, Fishman E, He J, Burkhart R, Shin E, Lennon A, Goggins M. Pancreatic Cancer Surveillance and Survival of High-Risk Individuals. JAMA Oncology 2024, 10: 1087-1096. PMID: 38959011, PMCID: PMC11223057, DOI: 10.1001/jamaoncol.2024.1930.Peer-Reviewed Original ResearchHigh-risk individualsSurveillance of high-risk individualsScreening programPancreatic ductal adenocarcinomaScreening high-risk individualsPancreatic cancer surveillanceUS academic medical centersPopulation-based screeningConditional logistic regressionUS national dataCox proportional hazards regressionAcademic medical centerLead-time biasProportional hazards regressionYear of diagnosisControl patientsRisk regression modelCancer surveillanceComparative cohort studyMain OutcomesComparison cohortOverall survivalCohort studyHazards regressionNational data
2023
Surveillance of Individuals at High Risk of Developing Pancreatic Cancer
Paiella S, Secchettin E, Lionetto G, Archibugi L, Azzolina D, Casciani F, Simeone D, Overbeek K, Goggins M, Farrell J, de Leon Pisani R, Tridenti M, Corciulo M, Malleo G, Arcidiacono P, Falconi M, Gregori D, Bassi C, Salvia R, Capurso G. Surveillance of Individuals at High Risk of Developing Pancreatic Cancer. Annals Of Surgery 2023, 279: 37-44. PMID: 37681303, DOI: 10.1097/sla.0000000000006094.Peer-Reviewed Original ResearchConceptsPancreatic cancer surveillanceHigh-risk individualsCancer surveillancePancreatic cancerPooled prevalenceFinal diagnosisPancreatic cancer subjectsLow-grade dysplasiaDysplastic precursor lesionsNon-neoplastic conditionsPathogenic variant carriersPancreatic resectionSecondary outcomesPooled proportionSubgroup analysisTarget lesionsPrecursor lesionsSurveillance of individualsCancer subjectsVariant carriersEffect modifiersHigh riskHereditary predispositionSurgeryPathogenic variantsRacial, Ethnic, and Sex-based Disparities among High-risk Individuals Undergoing Pancreatic Cancer Surveillance.
Katona B, Klute K, Brand R, Everett J, Farrell J, Hawthorne K, Kaul V, Kupfer S, Paiella S, Simeone D, Sussman D, Zogopoulos G, Lucas A, Kastrinos F, Bi Y, Brentnall T, Chung D, Earl J, Gaddam S, Gallinger S, Graff J, Greenhalf W, Grossberg A, Hart P, Idos G, Jeter J, Lindberg J, Lowy A, Permuth J, Raitses-Gurevich M, Schrader I, Siveke J, Stoffel E, Vornhuelz M, Wadlow R. Racial, Ethnic, and Sex-based Disparities among High-risk Individuals Undergoing Pancreatic Cancer Surveillance. Cancer Prevention Research 2023, 16: 343-352. PMID: 37259800, DOI: 10.1158/1940-6207.capr-22-0529.Peer-Reviewed Original ResearchConceptsHigh-risk individualsSex-based disparitiesPancreatic cancer surveillancePathogenic variantsPDAC surveillanceCancer surveillanceGuideline-based criteriaPancreatic cancer mortalityCommon age rangeRates of consentRace/ethnicityCancer criteriaRelated SpotlightMajority of participantsCancer mortalityHispanic ethnicitySurveillance studyDiverse patientsStudy participantsAge rangeTwo yearsSurveillanceEnrollmentEnrollment disparitiesParticipantsSu1423 ARE PANCREATIC CYSTS HIGH-YIELD IMAGING TARGETS DURING PANCREATIC CANCER SURVEILLANCE OF HIGH-RISK INDIVIDUALS? A SYSTEMATIC REVIEW AND META-ANALYSIS.
Woodbine M, Chhoda A, Silva-Santisteban A, Igbinedion S, Sur A, Germansky K, Farrell J, Sawhney M. Su1423 ARE PANCREATIC CYSTS HIGH-YIELD IMAGING TARGETS DURING PANCREATIC CANCER SURVEILLANCE OF HIGH-RISK INDIVIDUALS? A SYSTEMATIC REVIEW AND META-ANALYSIS. Gastroenterology 2023, 164: s-607. DOI: 10.1016/s0016-5085(23)02416-2.Peer-Reviewed Original ResearchRacial, ethnic, and sex-based disparities among high-risk individuals undergoing pancreatic cancer surveillance.
Klute K, Lucas A, Brand R, Everett J, Farrell J, Hawthorne K, Kaul V, Kupfer S, Paiella S, Simeone D, Sussman D, Zogopoulos G, Kastrinos F, Katona B, Consortium A. Racial, ethnic, and sex-based disparities among high-risk individuals undergoing pancreatic cancer surveillance. Journal Of Clinical Oncology 2023, 41: 687-687. DOI: 10.1200/jco.2023.41.4_suppl.687.Peer-Reviewed Original ResearchHigh-risk individualsSex-based disparitiesFamilial pancreatic cancerPDAC surveillancePancreatic cancer surveillancePeutz-Jeghers syndromeRates of consentSex-based differencesMedian ageAshkenazi Jewish ancestryMulticenter studyProspective studyCancer surveillancePancreatic cancerFamily historyLarge cohortMelanoma syndromeHereditary pancreatitisEarly detection researchStudy participantsEarly detectionStudy periodGermline DNACohortPDAC
2021
ID: 3527197 ENDOSCOPIC ULTRASOUND SHEAR WAVE ELASTOGRAPHY (SWE) FOR HIGH RISK INDIVIDUAL PANCREATIC CANCER SURVEILLANCE: A PILOT STUDY
Chhoda A, Merenda S, Farrell J. ID: 3527197 ENDOSCOPIC ULTRASOUND SHEAR WAVE ELASTOGRAPHY (SWE) FOR HIGH RISK INDIVIDUAL PANCREATIC CANCER SURVEILLANCE: A PILOT STUDY. Gastrointestinal Endoscopy 2021, 93: ab262-ab263. DOI: 10.1016/j.gie.2021.03.561.Peer-Reviewed Original ResearchSa293 ASSESSMENT OF PROGRESSION OF CHRONIC PANCREATITIS-LIKE LESIONS IN HIGH RISK INDIVIDUALS UNDERGOING PANCREATIC CANCER SURVEILLANCE
Chhoda A, Merenda S, Farrell J. Sa293 ASSESSMENT OF PROGRESSION OF CHRONIC PANCREATITIS-LIKE LESIONS IN HIGH RISK INDIVIDUALS UNDERGOING PANCREATIC CANCER SURVEILLANCE. Gastroenterology 2021, 160: s-473-s-474. DOI: 10.1016/s0016-5085(21)01836-9.Peer-Reviewed Original Research
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