2002
Bayesian analysis of gene expression levels: statistical quantification of relative mRNA level across multiple strains or treatments
Townsend JP, Hartl DL. Bayesian analysis of gene expression levels: statistical quantification of relative mRNA level across multiple strains or treatments. Genome Biology 2002, 3: research0071.1. PMID: 12537560, PMCID: PMC151173, DOI: 10.1186/gb-2002-3-12-research0071.Peer-Reviewed Original ResearchMeSH KeywordsBayes TheoremDNA-Binding ProteinsEthanolGene DeletionGene Expression ProfilingGene Expression Regulation, FungalGenotypeModels, GeneticNuclear ProteinsOligonucleotide Array Sequence AnalysisRNA, FungalRNA, MessengerSaccharomyces cerevisiae ProteinsSpecies SpecificityTranscription FactorsZincConceptsGene of interestExpression levelsGene expression levelsTwofold thresholdGene basisTranscriptional responseMicroarray comparisonsMinimal mediumExpression differencesBiological insightsMicroarray analysisEthanol shockMicroarray dataRelative mRNA levelsGenesMRNA levelsMultiple strainsBayesian analysisDevelopmental state
2000
Manifold anomalies in gene expression in a vineyard isolate of Saccharomyces cerevisiae revealed by DNA microarray analysis
Cavalieri D, Townsend J, Hartl D. Manifold anomalies in gene expression in a vineyard isolate of Saccharomyces cerevisiae revealed by DNA microarray analysis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 12369-12374. PMID: 11035792, PMCID: PMC17348, DOI: 10.1073/pnas.210395297.Peer-Reviewed Original ResearchConceptsDNA microarray analysisGene expressionNatural populationsSaccharomyces cerevisiaeMicroarray analysisGenome-wide transcriptional profilingAmino acid permeasesAmino acid biosynthesisSuite of traitsGlobal expression analysisSmooth colony phenotypeExtent of heterozygosityGlobal patternsVineyard isolateGene functionEvolutionary biologyNitrogen assimilationAcid biosynthesisSingle geneTranscriptional profilingUnlinked lociColony phenotypeHomothallic strainsS. cerevisiaeDiploid progeny