2012
Pre-steady state kinetic analysis of cyclobutyl derivatives of 2′-deoxyadenosine 5′-triphosphate as inhibitors of HIV-1 reverse transcriptase
Kim J, Wang L, Li Y, Becnel K, Frey K, Garforth S, Prasad V, Schinazi R, Liotta D, Anderson K. Pre-steady state kinetic analysis of cyclobutyl derivatives of 2′-deoxyadenosine 5′-triphosphate as inhibitors of HIV-1 reverse transcriptase. Bioorganic & Medicinal Chemistry Letters 2012, 22: 4064-4067. PMID: 22595174, PMCID: PMC3362660, DOI: 10.1016/j.bmcl.2012.04.078.Peer-Reviewed Original ResearchConceptsInhibitors of HIV-1 reverse transcriptaseCyclobutyl derivativesCompound 5HIV-1 reverse transcriptasePre-steady state kinetic analysisHIV-1 RTHIV inhibitorsTFV-DPHIV-1Kinetic analysis
1997
Pre-steady state kinetic analysis of the bifunctional human amino-imidazole carboxamide ribonucleotide formyltransferase/AMP cyclohydrolase (AICARFT/IMPCHase), a 10-formyltetrahydro-folate-requiring enzyme essential for de novo purine biosynthesis
Rayl E, Moroson B, Beardsley G, Anderson K. Pre-steady state kinetic analysis of the bifunctional human amino-imidazole carboxamide ribonucleotide formyltransferase/AMP cyclohydrolase (AICARFT/IMPCHase), a 10-formyltetrahydro-folate-requiring enzyme essential for de novo purine biosynthesis. Clinical Biochemistry 1997, 30: 275-276. DOI: 10.1016/s0009-9120(97)87769-7.Peer-Reviewed Original ResearchDe novo purine biosynthesisPre-steady state kinetic analysisPurine biosynthesisKinetic analysisBiosynthesisCyclohydrolaseEnzyme