Frank Buono, PhD
Research Scientist in PsychiatryCards
About
Research
Publications
2025
The development of an artificial intelligence auto-segmentation tool for 3D volumetric analysis of vestibular schwannomas
Jester N, Singh M, Lorr S, Tommasini S, Wiznia D, Buono F. The development of an artificial intelligence auto-segmentation tool for 3D volumetric analysis of vestibular schwannomas. Scientific Reports 2025, 15: 5918. PMID: 39966622, PMCID: PMC11836447, DOI: 10.1038/s41598-025-88589-x.Peer-Reviewed Original ResearchConceptsGround-truth datasetDice scoreVestibular schwannomaImage processing accuracyVolumetric analysisML-based algorithmsMeasuring tumor sizeMean dice scoreAuto-segmentation toolAccurate AIAI modelsTumor sizeTumor modelVS tumorsTumor growthTesting stageAI-LTumorImage processing softwareClinical practicePatient recruitmentProcessing softwareSchwannomaDatasetManual segmentationANTIPSYCHOTIC AGENTS IN ANXIETY DISORDERS: AN UMBRELLA REVIEW
Freire *, Garakani A, Buono F, Salehi M, Funaro M, Klimowicz A, Sharma H, Faria C, Larkin K. ANTIPSYCHOTIC AGENTS IN ANXIETY DISORDERS: AN UMBRELLA REVIEW. The International Journal Of Neuropsychopharmacology 2025, 28: i29-i29. PMCID: PMC11814792, DOI: 10.1093/ijnp/pyae059.051.Peer-Reviewed Original ResearchSecond-generation antipsychoticsFirst-generation antipsychoticsGeneralized anxiety disorderStudies of antipsychoticsAnxiety disordersAtypical antipsychoticsAntipsychotic agentsShort-term treatment of generalized anxiety disorderTreatment of generalized anxiety disorderEfficacy of first-generation antipsychoticsTreatment-resistant anxiety disordersEfficacy of antipsychotic agentsObsessive-compulsive disorderTreatment of anxietyEffective short-term treatmentMeta-analysesManagement of anxietyAntidepressant treatmentAntipsychotic medicationPosttraumatic stressAntipsychoticsAnxietyComparing monotherapyFirst-line treatmentMeta-analysis
2024
Comparing the Accuracy and Reliability of ABC/2 and Planimetry for Vestibular Schwannoma Volume Assessment
Singh K, Abdou H, Panth N, Chiang V, Buono F, Schwartz N, Mahajan A. Comparing the Accuracy and Reliability of ABC/2 and Planimetry for Vestibular Schwannoma Volume Assessment. Otology & Neurotology 2024, 46: 196-200. PMID: 39792983, DOI: 10.1097/mao.0000000000004392.Peer-Reviewed Original ResearchConceptsTumor volume assessmentABC/2 methodVestibular schwannomaVolume assessmentPlanimetry methodTumor volumeTumor volume changesFollow-up scansOverestimate tumor volumePatients' quality of lifeTumor sizeRetrospective reviewIntracranial tumorsImprove clinical decision makingSubgroup analysisVolumetric assessmentTumorClinical decision makingQuality of lifePatients' qualityPatientsClinical settingPlanimetryImaging techniquesPositive correlationUnderstanding Therapeutic Experience: A Qualitative Evaluation of Virtual and In-Person Treatment
Cerrito B, Connors A, Fialk A, Xiao J, Buono F. Understanding Therapeutic Experience: A Qualitative Evaluation of Virtual and In-Person Treatment. Cureus 2024, 16: e75392. PMID: 39781144, PMCID: PMC11709419, DOI: 10.7759/cureus.75392.Peer-Reviewed Original ResearchTherapy Mode Preference Scale: Preliminary Validation Methodological Design
Cerrito B, Xiao J, Fialk A, Buono F. Therapy Mode Preference Scale: Preliminary Validation Methodological Design. JMIR Formative Research 2024, 8: e65477. PMID: 39612373, PMCID: PMC11623782, DOI: 10.2196/65477.Peer-Reviewed Original ResearchConceptsZoom Exhaustion and Fatigue scaleIn-person careHierarchical linear regressionHealth careIn-personExploratory factor analysisInternal consistencyMental health treatment programsSatisfactory levels of internal consistencyFactor analysisLevels of internal consistencyIn-person therapyKaiser-Meyer-Olkin measure of sampling adequacyClient Satisfaction QuestionnaireKaiser-Meyer-Olkin measureBartlett's test of sphericityHealth care demandBarriers to treatmentMeasure of sampling adequacyTest of sphericityIncremental validityFactor structureFatigue ScaleLinear regressionCare demandsThe Road to Reintegration: Evaluating the Effectiveness of VA Healthcare in Vocational Rehabilitation and Employment Retention for Veterans with Mental Health and Substance Use Disorders
Sprong M, Hollender H, Blankenberger B, Rumrill S, Lee Y, Bland T, Bailey J, Weber K, Gilbert J, Kriz K, Buono F. The Road to Reintegration: Evaluating the Effectiveness of VA Healthcare in Vocational Rehabilitation and Employment Retention for Veterans with Mental Health and Substance Use Disorders. Substance Abuse And Rehabilitation 2024, 15: 107-123. PMID: 39081876, PMCID: PMC11287469, DOI: 10.2147/sar.s462882.Peer-Reviewed Original ResearchMental health treatmentSubstance use disorder treatmentVeterans Integrated Service NetworkVocational rehabilitation servicesVocational rehabilitation programVocational rehabilitationSubstance use disordersMental healthHealth treatmentProgram enrollmentRehabilitation servicesRehabilitation programVA healthcareVA healthcare systemSubstance use disorder treatment servicesProgram evaluation dataFace significant barriersProgram evaluation designMultivariate logistic regression analysisHealth outcomesLogistic regression analysisIntegrated services networksVeteran patientsHealthcare systemPost-dischargeVirtual Reality in Medical Education
Buono F, Marks A, Lee D. Virtual Reality in Medical Education. Cyberpsychology Behavior And Social Networking 2024, 27: 361-362. PMID: 38841871, DOI: 10.1089/cyber.2024.27599.geditorial.Peer-Reviewed Original ResearchAntipsychotic agents in anxiety disorders: An umbrella review
Garakani A, Buono F, Salehi M, Funaro M, Klimowicz A, Sharma H, Faria C, Larkin K, Freire R. Antipsychotic agents in anxiety disorders: An umbrella review. Acta Psychiatrica Scandinavica 2024, 149: 295-312. PMID: 38382649, DOI: 10.1111/acps.13669.Peer-Reviewed Original ResearchSecond-generation antipsychoticsFirst-generation antipsychoticsGeneralized anxiety disorderStudies of antipsychoticsAnxiety disordersAntipsychotic agentsEfficacy of first-generation antipsychoticsTreatment of anxiety disordersEfficacy of antipsychotic agentsMeta-analysesAntidepressant treatmentNonantipsychotic medicationsAntipsychoticsFirst-line treatmentAnxietyComparing monotherapyUmbrella reviewDisordersQuetiapineSystematic reviewSide effectsAMSTAR-2Off-labelAPA PsycInfoCINAHL CompleteUnderstanding chronic pain in Neurofibromatosis Type 1 using the Neurofibromatosis Pain Module (NFPM)
Buono F, Larkin K, Zempsky W, Grau L, Martin S. Understanding chronic pain in Neurofibromatosis Type 1 using the Neurofibromatosis Pain Module (NFPM). American Journal Of Medical Genetics Part A 2024, 194: e63541. PMID: 38234177, DOI: 10.1002/ajmg.a.63541.Peer-Reviewed Original ResearchNeurofibromatosis type 1Chronic painImpact of CPPain modulationPain regionsModerate pain severityType 1Autosomal dominant genetic disorderCross-sectional studyQuality of lifeDominant genetic disorderMedical providersPain severitySensitive clinical measureDaily functioningClinical measuresPainEffective treatmentGenetic disordersNeurofibromatosisClinical assessmentMultiple domainsAdultsQuantitative responseProviders
2023
Recommendations for assessing appearance concerns related to plexiform and cutaneous neurofibromas in neurofibromatosis 1 clinical trials
Merker V, Thompson H, Wolters P, Buono F, Hingtgen C, Rosser T, Barton B, Barnett C, Smith T, Haberkamp D, McManus M, Baldwin A, Moss I, Röhl C, Martin S. Recommendations for assessing appearance concerns related to plexiform and cutaneous neurofibromas in neurofibromatosis 1 clinical trials. Clinical Trials 2023, 21: 6-17. PMID: 38140900, PMCID: PMC10922038, DOI: 10.1177/17407745231205577.Peer-Reviewed Original ResearchPatient-reported outcome measuresClinical trialsOutcome measuresNeurofibromatosis 1Cutaneous neurofibromasDistress ScaleOlder adultsFinal consensus recommendationsKey secondary outcomesPatient-reported outcomesPatient-reported changesAppearance concernsSystematic literature searchNontumor manifestationsTreatment sequelaeSecondary outcomesBACKGROUND/Consensus recommendationsPatient's perspectiveTumor volumePatient representativesGood psychometric propertiesOutcome ratingsLiterature searchPlexiform
News & Links
News
- August 07, 2024
Grant to Help Team Develop Dynamic 3D Tumor Analysis
- June 21, 2024Source: Cyberpsychology, Behavior, and Social Networking
Buono, Marks Guest Edit Special Issue of 'Cyberpsychology, Behavior and Social Networking'
- May 21, 2024
Garakani, Buono Awarded Grant from AAPL Institute for Education and Research
- April 26, 2024
Buono, Cortes-Briones, Lee Honored with 2024 Blavatnik Awards
Get In Touch
Contacts
Email
Mobile Phone Number
Academic Office Number
Mailing Address
Yale School of Medicine
300 George Street
New Haven, CT 06510
United States