2009
Ovarian Preservation and Staging in Reproductive-Age Endometrial Cancer Patients
Richter C, Qian B, Martel M, Yu H, Azodi M, Rutherford T, Schwartz P. Ovarian Preservation and Staging in Reproductive-Age Endometrial Cancer Patients. Obstetrical & Gynecological Survey 2009, 64: 726-727. DOI: 10.1097/01.ogx.0000361368.51892.57.Peer-Reviewed Original ResearchDisease-free survivalLonger disease-free survivalSurgical stagingEndometrial cancerOvarian preservationClinical stagingPremenopausal womenEndometrial carcinomaEarly-stage low-grade endometrial cancerEarly-stage endometrial cancerEarly-stage endometrial carcinomaLow-grade endometrial cancerYoung womenLong-term adverse effectsAggressive surgical stagingGrade 1 diseaseStage endometrial cancerEndometrial cancer patientsStage 1 diseaseTotal abdominal hysterectomyEarly-stage patientsLonger overall survivalLarge university hospitalQuality of lifeParaaortic lymphadenectomy
2008
High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-β1
Qian B, Katsaros D, Lu L, Preti M, Durando A, Arisio R, Mu L, Yu H. High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-β1. Breast Cancer Research And Treatment 2008, 117: 131-140. PMID: 18932017, DOI: 10.1007/s10549-008-0219-7.Peer-Reviewed Original ResearchConceptsMiR-21 expressionPoor disease-free survivalHigh miR-21 expressionDisease-free survivalHormone receptor statusHigh miR-21Breast cancerMiR-21Tumor samplesReceptor statusTumor gradeTGF-β1Elevated miR-21 expressionNegative hormone receptor statusProportional hazards regression analysisHigher TGF-β1Lymph node involvementEarly-stage diseaseEarly-stage patientsPrimary breast cancerHazards regression analysisHigh tumor gradeFresh tumor samplesTumor cell growthNode involvement