2020
A general-purpose Monte Carlo particle transport code based on inverse transform sampling for radiotherapy dose calculation
Liang Y, Muhammad W, Hart GR, Nartowt BJ, Chen ZJ, Yu JB, Roberts KB, Duncan JS, Deng J. A general-purpose Monte Carlo particle transport code based on inverse transform sampling for radiotherapy dose calculation. Scientific Reports 2020, 10: 9808. PMID: 32555530, PMCID: PMC7300009, DOI: 10.1038/s41598-020-66844-7.Peer-Reviewed Original ResearchConceptsPhoton transportBoundary crossing algorithmMonte Carlo particle transport codeMonte Carlo methodTransport simulationsAcceptance-rejection samplingRadiotherapy dose calculationsPhoto-electric effectParticle transport codeEGSnrc simulationsCarlo methodBremsstrahlung eventsInelastic scatteringPair productionRayleigh scatteringThread divergenceMC simulationsTransport codeMC codeHistory schemeParticle transportCrossing algorithmInverseElectron transportSimulation accuracy
2019
Beam modeling and beam model commissioning for Monte Carlo dose calculation‐based radiation therapy treatment planning: Report of AAPM Task Group 157
Charlie C, Chetty IJ, Deng J, Faddegon B, Jiang SB, Li J, Seuntjens J, Siebers JV, Traneus E. Beam modeling and beam model commissioning for Monte Carlo dose calculation‐based radiation therapy treatment planning: Report of AAPM Task Group 157. Medical Physics 2019, 47: e1-e18. PMID: 31679157, DOI: 10.1002/mp.13898.Peer-Reviewed Original ResearchMeSH KeywordsModels, TheoreticalMonte Carlo MethodRadiation DosageRadiotherapy DosageRadiotherapy Planning, Computer-AssistedResearch ReportConceptsBeam modelElectron beam dose calculationsMonte Carlo methodRadiotherapy dose calculationsTreatment planning systemDose calculationsClinical beam modelCarlo methodBeam modelingRadiation therapy treatment planningMC simulationsTherapy treatment planningElectron beamTreatment headClinical photonRadiotherapy treatment planningGeneral approachCalculationsHigh accuracyPractical procedureAccuracyModelClinical physicistsAnalytical methodBeam delivery
2018
Imaging Dose, Cancer Risk and Cost Analysis in Image-guided Radiotherapy of Cancers
Zhou L, Bai S, Zhang Y, Ming X, Zhang Y, Deng J. Imaging Dose, Cancer Risk and Cost Analysis in Image-guided Radiotherapy of Cancers. Scientific Reports 2018, 8: 10076. PMID: 29973695, PMCID: PMC6031630, DOI: 10.1038/s41598-018-28431-9.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBone Marrow CellsBrainChildChild, PreschoolCone-Beam Computed TomographyCost-Benefit AnalysisFemaleHumansInfantLungMaleMiddle AgedMonte Carlo MethodNeoplasmsPhantoms, ImagingRadiation DosageRadiotherapy DosageRadiotherapy, Image-GuidedRisk FactorsThoraxYoung AdultConceptsCancer riskAssociated cancer riskImage-guided radiotherapyImaging proceduresLifetime attributable riskImaging dosesAverage lifetime attributable riskRadiological imaging proceduresRed bone marrowRetrospective studyCancer patientsLung cancerAttributable riskCancer incidenceBilling codesIndividual patientsBone marrowBrain cancerImage guidance proceduresPelvic scanPatientsCancerOrgan dosesRadiotherapyDoses
2017
Personalized and Conscientious Medical Imaging: To Image or Not to Image
Deng J. Personalized and Conscientious Medical Imaging: To Image or Not to Image. JAMA Oncology 2017, 3: 443-444. PMID: 27466980, PMCID: PMC5857946, DOI: 10.1001/jamaoncol.2016.2220.Peer-Reviewed Original ResearchA measurement-based generalized source model for Monte Carlo dose simulations of CT scans
Ming X, Feng Y, Liu R, Yang C, Zhou L, Zhai H, Deng J. A measurement-based generalized source model for Monte Carlo dose simulations of CT scans. Physics In Medicine And Biology 2017, 62: 1759-1776. PMID: 28079526, PMCID: PMC5857954, DOI: 10.1088/1361-6560/aa5911.Peer-Reviewed Original ResearchConceptsMonte Carlo dose simulationsGeneralized source modelEnergy spectrumFluence distributionDose profilesCentral axis percent depth dose curvePercent depth dose curvesDose simulationsDepth dose curvesMonte Carlo user codeSource distributionBeam inputDose curvesFilm measurementsCTDI phantomCT scannerOutput factorsAbsolute dose comparisonsMonte Carlo simulationsDose distributionSource modelCarlo simulationsCircular sourceGE LightspeedScanner specifications
2015
In Reply to Wang et al
Zhang Y, Feng Y, Zhang Y, Ming X, Yu J, Carlson D, Kim J, Deng J. In Reply to Wang et al. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: 211-213. PMID: 26279038, DOI: 10.1016/j.ijrobp.2015.04.010.Peer-Reviewed Original ResearchConcomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy
Zhang Y, Wu H, Chen Z, Knisely JP, Nath R, Feng Z, Bao S, Deng J. Concomitant Imaging Dose and Cancer Risk in Image Guided Thoracic Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: 523-531. PMID: 26460994, DOI: 10.1016/j.ijrobp.2015.06.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAorta, ThoracicBody SizeBreastChildChild, PreschoolCone-Beam Computed TomographyFemaleHeartHumansLungMaleMiddle AgedMonte Carlo MethodOrgans at RiskPhantoms, ImagingPhotonsPrecision MedicineProtonsRadiation DosageRadiography, ThoracicRadiotherapy, Image-GuidedRisk AssessmentSex FactorsSpinal CordThoracic WallThoraxConceptsConcomitant imaging doseThoracic radiation therapyCancer riskRadiation therapyMean dosesCardiac substructuresKilovoltage cone-beamImaging doseAdverse eventsPediatric patientsMedian dosesCancer patientsRight ventricleExtra radiation doseSpinal cordHigh dosesPatientsCone beamPlanning CT imagesChest dimensionsDosesPatient sizeImaging guidanceTherapyDoseIs It the Time for Personalized Imaging Protocols in Cancer Radiation Therapy?
Zhang Y, Feng Y, Zhang Y, Ming X, Yu J, Carlson DJ, Kim J, Deng J. Is It the Time for Personalized Imaging Protocols in Cancer Radiation Therapy? International Journal Of Radiation Oncology • Biology • Physics 2015, 91: 659-660. PMID: 25680605, DOI: 10.1016/j.ijrobp.2014.10.044.Peer-Reviewed Original Research
2012
CT scans in childhood and risk of leukaemia and brain tumours
Deng J, Zhang Y, Nath R, Bao S. CT scans in childhood and risk of leukaemia and brain tumours. The Lancet 2012, 380: 1735. PMID: 23158242, DOI: 10.1016/s0140-6736(12)61980-1.Peer-Reviewed Original ResearchPersonalized estimation of dose to red bone marrow and the associated leukaemia risk attributable to pelvic kilo-voltage cone beam computed tomography scans in image-guided radiotherapy
Zhang Y, Yan Y, Nath R, Bao S, Deng J. Personalized estimation of dose to red bone marrow and the associated leukaemia risk attributable to pelvic kilo-voltage cone beam computed tomography scans in image-guided radiotherapy. Physics In Medicine And Biology 2012, 57: 4599-4612. PMID: 22750636, DOI: 10.1088/0031-9155/57/14/4599.Peer-Reviewed Original ResearchConceptsKilo-voltage cone beamRed bone marrowLeukemia riskRBM doseImage-guided radiation therapyTomography scanBone marrowCone beamRadiogenic cancer riskRadiation therapy courseCancer patientsBone densityImage-guided radiotherapyRadiation therapyCancer riskHigh riskPersonalized estimationAnthropometric variablesTherapy courseDoseSubject groupsDosesBone dosesScansPatientsPersonalized Assessment of kV Cone Beam Computed Tomography Doses in Image-guided Radiotherapy of Pediatric Cancer Patients
Zhang Y, Yan Y, Nath R, Bao S, Deng J. Personalized Assessment of kV Cone Beam Computed Tomography Doses in Image-guided Radiotherapy of Pediatric Cancer Patients. International Journal Of Radiation Oncology • Biology • Physics 2012, 83: 1649-1654. PMID: 22285667, DOI: 10.1016/j.ijrobp.2011.10.072.Peer-Reviewed Original ResearchAdolescentAge FactorsBody SizeBody WeightChildChild, PreschoolCone-Beam Computed TomographyFemaleHeadHumansMaleMonte Carlo MethodNeoplasmsOrgans at RiskPelvisPhantoms, ImagingRadiation DosageRadiation InjuriesRadiotherapy Planning, Computer-AssistedRadiotherapy, Image-GuidedRetrospective StudiesYoung Adult
2011
Kilovoltage Imaging Doses in the Radiotherapy of Pediatric Cancer Patients
Deng J, Chen Z, Roberts KB, Nath R. Kilovoltage Imaging Doses in the Radiotherapy of Pediatric Cancer Patients. International Journal Of Radiation Oncology • Biology • Physics 2011, 82: 1680-1688. PMID: 21477943, DOI: 10.1016/j.ijrobp.2011.01.062.Peer-Reviewed Original ResearchConceptsPediatric cancer patientsCancer patientsTesticular shieldingSpinal cordKilovoltage cone-beamCBCT dosesMean dosesClinical conditionsDose reductionLarge dosesFemoral headPatientsCBCT scansCone beamDosesFull-fan modeOptical nerveCBCT fieldCordDose increaseImaging dosesScanning protocolOARsRadiotherapyHalf-fan mode
2006
Evaluation of the EDR-2 film for relative dosimetry of high-energy photon and electron beams
Ahmad M, Chen Z, Song H, Deng J, Nath R. Evaluation of the EDR-2 film for relative dosimetry of high-energy photon and electron beams. Radiation Protection Dosimetry 2006, 120: 159-162. PMID: 16644932, DOI: 10.1093/rpd/ncj006.Peer-Reviewed Original ResearchConceptsEDR-2 filmsElectron beamRelative dosimetryHigh-energy photonsClinical radiation dosimetryDose profilesPhotonsRadiation dosimetryBeamDose distributionRadiographic filmsSensitometric studyFilmsDosimetryTreatment planning techniquesElectronsDiodesSymmetryKVFlatnessPlanning techniquesDistribution