2024
An Introduction and Practical Guide to Strategies for Analyzing Longitudinal Data in Clinical Trials of Smoking Cessation Treatment: Beyond Dichotomous Point-Prevalence Outcomes
Kypriotakis G, Bernstein S, Bold K, Dziura J, Hedeker D, Mermelstein R, Weinberger A. An Introduction and Practical Guide to Strategies for Analyzing Longitudinal Data in Clinical Trials of Smoking Cessation Treatment: Beyond Dichotomous Point-Prevalence Outcomes. Nicotine & Tobacco Research 2024, 26: 796-805. PMID: 38214037, PMCID: PMC11190044, DOI: 10.1093/ntr/ntae005.Peer-Reviewed Original ResearchSmoking cessation treatmentChronic relapsing conditionCessation treatmentRelapsing conditionSmoking cessation clinical trialMeasures of abstinenceTobacco useAbstinence outcomesTobacco dependence treatmentTobacco abstinenceTobacco dependenceTobacco outcomesDependence treatmentTreatment studiesAbstinenceSmoking cessationClinical trialsIntervention successParticipant enrollmentSociety for ResearchNicotineLongitudinal dataResearch NetworkRemitting natureAnalysis of data
2016
Urgency traits moderate daily relations between affect and drinking to intoxication among young adults
Bold KW, Fucito LM, DeMartini KS, Leeman RF, Kranzler HR, Corbin WR, O’Malley S. Urgency traits moderate daily relations between affect and drinking to intoxication among young adults. Drug And Alcohol Dependence 2016, 170: 59-65. PMID: 27875802, PMCID: PMC5183550, DOI: 10.1016/j.drugalcdep.2016.10.035.Peer-Reviewed Original ResearchConceptsYoung adultsHeavy drinkingEffectiveness of naltrexoneBlood alcohol concentrationHeavy drinking young adultsBrief motivational interventionNaltrexone treatmentClinical trialsHazardous drinkingNaltrexoneSecondary analysisPlaceboTargeted interventionsAge 18Alcohol useIntoxicationLow urgencyAdultsMotivational interventionDrinkingTrait urgencyOddsInterventionCurrent studyRiskDaily Relations Among Affect, Urge, Targeted Naltrexone, and Alcohol Use in Young Adults
Bold KW, Fucito LM, Corbin WR, DeMartini KS, Leeman RF, Kranzler HR, O’Malley S. Daily Relations Among Affect, Urge, Targeted Naltrexone, and Alcohol Use in Young Adults. Experimental And Clinical Psychopharmacology 2016, 24: 367-375. PMID: 27690505, PMCID: PMC5111359, DOI: 10.1037/pha0000090.Peer-Reviewed Original ResearchConceptsYoung adultsDouble-blind clinical trialHeavy drinkingSerious public health problemDose of medicationPublic health problemAlcohol-related interventionsTargeted naltrexoneNaltrexone groupOpioid antagonistRisk factorsClinical trialsFamily historyNaltrexone effectsGreater oddsAlcohol consumptionHealth problemsAlcohol dependenceSecondary analysisPlaceboNaltrexoneNaltrexone's abilityAdultsMedicationsDrinking