2024
High-impact chronic pain in sickle cell disease: insights from the Pain in Sickle Cell Epidemiology Study (PiSCES)
Jagtiani A, Chou E, Gillespie S, Liu K, Krishnamurti L, McClish D, Smith W, Bakshi N. High-impact chronic pain in sickle cell disease: insights from the Pain in Sickle Cell Epidemiology Study (PiSCES). Pain 2024, 165: 2364-2369. PMID: 38787626, PMCID: PMC11404329, DOI: 10.1097/j.pain.0000000000003262.Peer-Reviewed Original ResearchHigh-impact chronic painSickle Cell Epidemiology StudyChronic painProportion of daysUS National Pain StrategySickle cell diseaseNational Pain StrategySelf-care activitiesEpidemiological studiesHigher levels of stressMean pain intensityCohort of individualsPain interferenceLevels of stressPhysical functionHealth outcomesHealthcare utilizationPhysical healthPain strategiesPain burdenPain intensityPain diaryCell diseaseDiary daysAffected subgroups
2022
Associated comorbidities, healthcare utilization & mortality in hospitalized patients with haemophilia in the United States: Contemporary nationally representative estimates
Day J, Takemoto C, Sharathkumar A, Makhani S, Gupta A, Bitner S, Josephson C, Bloch E, Tobian A, Krishnamurti L, Goel R. Associated comorbidities, healthcare utilization & mortality in hospitalized patients with haemophilia in the United States: Contemporary nationally representative estimates. Haemophilia 2022, 28: 532-541. PMID: 35412659, PMCID: PMC9540439, DOI: 10.1111/hae.14557.Peer-Reviewed Original ResearchConceptsNationwide Inpatient SampleHealthcare utilizationPrevalence of comorbiditiesAge-related comorbiditiesCentral line infectionsInpatient discharge databaseOverall mortality rateCatheter-related infectionsHealthcare utilization patternsMedian hospital chargesICD-10 codesRepresentative estimatesCause admissionsCause hospitalizationAdult PWHAssociated comorbidityCommon comorbiditiesHospitalized patientsMedian ageContemporary cohortHospital burdenHospital chargesDischarge databaseInpatient SampleLine infections
2019
Associated Co-Morbidities, Healthcare Utilization, and Mortality in Hospitalized Children and Adults with Hemophilia in the United States: Updated Nationally Representative Estimates and a Comparative Analysis
Gupta A, Hannan A, Maini R, Bitner S, Stone S, Regmi M, Tobian A, Josephson C, Krishnamurti L, Takemoto C, Goel R. Associated Co-Morbidities, Healthcare Utilization, and Mortality in Hospitalized Children and Adults with Hemophilia in the United States: Updated Nationally Representative Estimates and a Comparative Analysis. Blood 2019, 134: 4711. DOI: 10.1182/blood-2019-123161.Peer-Reviewed Original ResearchCongestive heart failureNationwide Inpatient SampleMedian hospital chargesHepatitis CMedian ageHIV/AIDSHospital dischargeInpatient mortalityHeart failureCommon diagnosisHealthcare utilizationHaemophilia patientsHospital chargesMortality rateHemophilia AUtilization Project Nationwide Inpatient SampleYounger ageCommon discharge diagnosesMost hemophilia patientsNon-bleeding complicationsInpatient mortality rateHepatitis C casesCentral line infectionsCoronary artery diseaseInsurance coverage
2018
A Qualitative Study of Chronic Pain and Self-Management in Adults with Sickle Cell Disease
Matthie N, Ross D, Sinha C, Khemani K, Bakshi N, Krishnamurti L. A Qualitative Study of Chronic Pain and Self-Management in Adults with Sickle Cell Disease. Journal Of The National Medical Association 2018, 111: 158-168. PMID: 30266214, PMCID: PMC6433553, DOI: 10.1016/j.jnma.2018.08.001.Peer-Reviewed Original ResearchConceptsSickle cell diseaseChronic pain managementChronic painChronic pain experiencePain managementCell diseasePain experienceChronic SCD painGreater QoL impairmentVaso-occlusive painYears of ageSelf-management strategiesSickle cell anemiaSubgroup of adultsSCD painAcute painPersistent painSubstantial morbidityHealthcare utilizationImpaired qualityQoL impairmentPainSCD managementCell anemiaQualitative study
2010
Burden of In-Hospital Care of Thrombotic Microangiopathies In the United States
Gupta A, Krishnamurti L. Burden of In-Hospital Care of Thrombotic Microangiopathies In the United States. Blood 2010, 116: 2559. DOI: 10.1182/blood.v116.21.2559.2559.Peer-Reviewed Original ResearchNationwide Inpatient SampleThrombotic microangiopathyHealth care utilizationRelated hospital admissionsHealthcare utilizationHospital dischargeHospital admissionCare utilizationHospital chargesTherapeutic plasmapheresisAge groupsFrequent healthcare encountersIn-Hospital CarePayer inpatient databaseClinical Modification codesAverage hospital chargesBurden of careNational dataFirst national dataStratified probability sampleU.S. community hospitalsTotal hospitalizationsFrequent hospitalizationsInpatient DatabaseMean duration