2022
Within‐ and between‐person effects of naltrexone on the subjective response to alcohol and craving: A daily diary investigation
Waddell JT, Corbin WR, MacKinnon DP, Leeman RF, DeMartini KS, Fucito LM, Kranzler HR, O’Malley S. Within‐ and between‐person effects of naltrexone on the subjective response to alcohol and craving: A daily diary investigation. Alcohol Clinical And Experimental Research 2022, 46: 477-491. PMID: 35076087, PMCID: PMC9679805, DOI: 10.1111/acer.14780.Peer-Reviewed Original ResearchConceptsMedication dosageYoung adultsLight drinkingSubjective responsesSubjective effectsHeavy drinkingPlacebo-controlled studyEffect sizePerson effectsEffective treatmentNaltrexoneDrinking daysNaltrexone efficacySmall effect sizesDrinking levelsCravingDrinkingAdultsLaboratory-based studiesPillsMomentary assessmentEfficacyTreatment conditionsDrinking environmentsDaily diary data
2021
Reward drinking and naltrexone treatment response among young adult heavy drinkers
Roos CR, Bold KW, Witkiewitz K, Leeman RF, DeMartini KS, Fucito LM, Corbin WR, Mann K, Kranzler HR, O'Malley SS. Reward drinking and naltrexone treatment response among young adult heavy drinkers. Addiction 2021, 116: 2360-2371. PMID: 33620746, PMCID: PMC8328878, DOI: 10.1111/add.15453.Peer-Reviewed Original ResearchA Multimodal Mobile Sleep Intervention for Young Adults Engaged in Risky Drinking: Protocol for a Randomized Controlled Trial (Preprint)
Fucito LM, Ash GI, DeMartini KS, Pittman B, Barnett NP, Li CR, Redeker NS, O'Malley SS. A Multimodal Mobile Sleep Intervention for Young Adults Engaged in Risky Drinking: Protocol for a Randomized Controlled Trial (Preprint). JMIR Research Protocols 2021, 10: e26557. PMID: 33635276, PMCID: PMC7954653, DOI: 10.2196/26557.Peer-Reviewed Original ResearchSleep hygiene adviceINTERNATIONAL REGISTERED REPORT IDENTIFIERHeavy-drinking young adultsHygiene adviceSleep interventionsYoung adultsAlcohol diaryAlcohol use disorder riskRisky alcohol consumptionAlcohol use disorderLow-cost interventionAlcohol behavior changeControlled TrialsWeb-based sessionsBrief adviceHealth coachesRisk factorsPoor sleepRecent heavy drinkingSleep characteristicsUse disordersAlcohol consumptionAlcohol-related consequencesPriority populationsSecondary aim
2020
Using Web-Based Social Media to Recruit Heavy-Drinking Young Adults for Sleep Intervention: Prospective Observational Study
Ash GI, Robledo DS, Ishii M, Pittman B, DeMartini KS, O'Malley SS, Redeker NS, Fucito LM. Using Web-Based Social Media to Recruit Heavy-Drinking Young Adults for Sleep Intervention: Prospective Observational Study. Journal Of Medical Internet Research 2020, 22: e17449. PMID: 32780027, PMCID: PMC7448185, DOI: 10.2196/17449.Peer-Reviewed Original ResearchConceptsAlcohol use disorderSleep interventionsSleep concernsYoung adultsAlcohol useWeb-based surveyBrief web-based surveyProspective observational studyHeavy-drinking young adultsYears of ageHigh response rateAlcohol prevention strategiesHeavy alcohol useAlcohol prevention programsHeavy drinking young adultsScreening eligibilityRisk factorsStudy enrolleesObservational studySleep programSleep problemsAlcohol screenerUse disordersPrevention strategiesResponse rate
2016
Urgency traits moderate daily relations between affect and drinking to intoxication among young adults
Bold KW, Fucito LM, DeMartini KS, Leeman RF, Kranzler HR, Corbin WR, O’Malley S. Urgency traits moderate daily relations between affect and drinking to intoxication among young adults. Drug And Alcohol Dependence 2016, 170: 59-65. PMID: 27875802, PMCID: PMC5183550, DOI: 10.1016/j.drugalcdep.2016.10.035.Peer-Reviewed Original ResearchConceptsYoung adultsHeavy drinkingEffectiveness of naltrexoneBlood alcohol concentrationHeavy drinking young adultsBrief motivational interventionNaltrexone treatmentClinical trialsHazardous drinkingNaltrexoneSecondary analysisPlaceboTargeted interventionsAge 18Alcohol useIntoxicationLow urgencyAdultsMotivational interventionDrinkingTrait urgencyOddsInterventionCurrent studyRiskDaily Relations Among Affect, Urge, Targeted Naltrexone, and Alcohol Use in Young Adults
Bold KW, Fucito LM, Corbin WR, DeMartini KS, Leeman RF, Kranzler HR, O’Malley S. Daily Relations Among Affect, Urge, Targeted Naltrexone, and Alcohol Use in Young Adults. Experimental And Clinical Psychopharmacology 2016, 24: 367-375. PMID: 27690505, PMCID: PMC5111359, DOI: 10.1037/pha0000090.Peer-Reviewed Original ResearchConceptsYoung adultsDouble-blind clinical trialHeavy drinkingSerious public health problemDose of medicationPublic health problemAlcohol-related interventionsTargeted naltrexoneNaltrexone groupOpioid antagonistRisk factorsClinical trialsFamily historyNaltrexone effectsGreater oddsAlcohol consumptionHealth problemsAlcohol dependenceSecondary analysisPlaceboNaltrexoneNaltrexone's abilityAdultsMedicationsDrinking
2015
Interactive and Indirect Effects of Anxiety and Negative Urgency on Alcohol‐Related Problems
Menary KR, Corbin WR, Leeman RF, Fucito LM, Toll BA, DeMartini K, O'Malley SS. Interactive and Indirect Effects of Anxiety and Negative Urgency on Alcohol‐Related Problems. Alcohol Clinical And Experimental Research 2015, 39: 1267-1274. PMID: 26031346, PMCID: PMC4490982, DOI: 10.1111/acer.12762.Peer-Reviewed Original ResearchConceptsNegative urgencyAlcohol problemsPotential moderatorsCoping-related drinking motivesDependence symptomsPrevention/intervention effortsNegative emotional statesIndirect effectsInteractive effectsAlcohol-related problemsCurrent cross-sectional studyAlcohol use disorderNegative affectDrinking motivesEmotional statesDrinking sampleModeration hypothesisIntervention effortsDirect interactive effectsAnxietyYoung adultsUse disordersLongitudinal dataModeratorPositive associationReduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety.
O'Malley SS, Corbin WR, Leeman RF, DeMartini KS, Fucito LM, Ikomi J, Romano DM, Wu R, Toll BA, Sher KJ, Gueorguieva R, Kranzler HR. Reduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety. The Journal Of Clinical Psychiatry 2015, 76: e207-13. PMID: 25742208, PMCID: PMC4442987, DOI: 10.4088/jcp.13m08934.Peer-Reviewed Original ResearchConceptsHeavy drinking daysBlood alcohol concentrationPercent days abstinentDrinking daysNumber of drinksYoung adultsDays abstinentPercent heavy drinking daysOutpatient research centerSafety of naltrexonePlacebo-controlled studySerious adverse eventsRisk-benefit ratioPercentage of daysAdverse eventsSecondary outcomesPrimary outcomeFrequency of drinkingOpioid antagonistAdult heavy drinkersAlcohol drinkingClinical trialsEvaluable samplesYoung adult heavy drinkersTreatment periodNovel Approaches to Individual Alcohol Interventions for Heavy Drinking College Students and Young Adults
DeMartini KS, Fucito LM, O’Malley S. Novel Approaches to Individual Alcohol Interventions for Heavy Drinking College Students and Young Adults. Current Addiction Reports 2015, 2: 47-57. PMID: 26258001, PMCID: PMC4524658, DOI: 10.1007/s40429-015-0043-1.Peer-Reviewed Original ResearchAlcohol interventionsAlcohol outcomesCollege studentsHeavy drinking college studentsYoung adultsNovel interventionsAlcohol-related problemsNovel treatment approachesIntervention efficacyTreat populationAlcohol useEfficacious interventionsTreatment approachesAlcohol consumptionTreatment integrationInterventionEfficacyLimited durationAdultsOutcomesStudentsUrgent needPopulationPrevalenceTrials
2014
In With the Old and Out With the New? A Comparison of the Old and New Binge Drinking Standards
Corbin WR, Zalewski S, Leeman RF, Toll BA, Fucito LM, O'Malley SS. In With the Old and Out With the New? A Comparison of the Old and New Binge Drinking Standards. Alcohol Clinical And Experimental Research 2014, 38: 2657-2663. PMID: 25346506, PMCID: PMC9328028, DOI: 10.1111/acer.12514.Peer-Reviewed Original ResearchConceptsIndex of intoxicationRandomized clinical trialsHeavy-drinking young adultsClinical trialsAlcohol abuseDrinking consequencesNegative drinking consequencesYoung adultsNational InstituteDrinking occasionsRiskConsistent evidenceIntoxicationRegression modelsTask ForceAdultsBrief measureDrinking sampleFurther effortsNegative consequencesBingeTrials
2013
Drinking Less and Drinking Smarter: Direct and Indirect Protective Strategies in Young Adults
DeMartini KS, Palmer RS, Leeman RF, Corbin WR, Toll BA, Fucito LM, O’Malley S. Drinking Less and Drinking Smarter: Direct and Indirect Protective Strategies in Young Adults. Psychology Of Addictive Behaviors 2013, 27: 615-626. PMID: 23088406, PMCID: PMC3869566, DOI: 10.1037/a0030475.Peer-Reviewed Original ResearchConceptsAlcohol-related consequencesClinical samplesYoung adult drinkingLow alcohol consumptionAdult drinkingPatient goalsYoung adult drinkersAlcohol consumptionProtective behavioral strategiesAlcohol useYoung adultsConfirmatory factor analysisProtective strategiesDrinking levelsLow drinking levelsAdult drinkersDrinkingDrinkersInterventionStrategies QuestionnaireCFA modelFactorsPredictors of Interest in an Alcohol Reduction Clinical Trial of Naltrexone among Undergraduates
Leeman RF, Corbin WR, Fucito LM, Urwin JW, O’Malley S. Predictors of Interest in an Alcohol Reduction Clinical Trial of Naltrexone among Undergraduates. Journal Of Addiction Research & Therapy 2013, 4: 151. PMID: 24511431, PMCID: PMC3917969, DOI: 10.4172/2155-6105.1000151.Peer-Reviewed Original ResearchClinical trialsPredictors of interestTrend-level predictorCurrent cigarette smokingNon-white raceCigarette smokingDrinking reductionsPast-year drinkersTreatment engagementHeavy drinkersReduction messagesAlcohol-related negative consequencesYoung adultsSignificant predictorsTrialsNaltrexonePredictorsRandom sampleDrinkersRegression modelsFull regression modelCounselingEquivalent levelsHigher numberMedicationsEarly Subjective Response and Acquired Tolerance as Predictors of Alcohol Use and Related Problems in a Clinical Sample
Corbin WR, Scott C, Leeman RF, Fucito LM, Toll BA, O'Malley SS. Early Subjective Response and Acquired Tolerance as Predictors of Alcohol Use and Related Problems in a Clinical Sample. Alcohol Clinical And Experimental Research 2013, 37: 490-497. PMID: 23347236, PMCID: PMC3586307, DOI: 10.1111/j.1530-0277.2012.01956.x.Peer-Reviewed Original ResearchConceptsEarly subjective responseLow subjective responseAlcohol use disorderAlcohol-related problemsRisk factorsSubjective responsesAlcohol useYoung adultsBrief motivational counselingClinical samplesInitial subjective responseDrinking behaviorHeavy drinking young adultsSignificant alcohol problemsClinical trialsProtective effectModerate drinkersUse disordersMotivational counselingPrior studiesCurrent studyHeavy drinkersHazardous drinkingAlcohol effectsWeekly drinking
2011
Co-occurring marijuana use is associated with medication nonadherence and nonplanning impulsivity in young adult heavy drinkers
Peters EN, Leeman RF, Fucito LM, Toll BA, Corbin WR, O'Malley SS. Co-occurring marijuana use is associated with medication nonadherence and nonplanning impulsivity in young adult heavy drinkers. Addictive Behaviors 2011, 37: 420-426. PMID: 22189052, PMCID: PMC3288288, DOI: 10.1016/j.addbeh.2011.11.036.Peer-Reviewed Original ResearchConceptsCo-occurring marijuana useAdult heavy drinkersYoung adult heavy drinkersHeavy drinkersMedication nonadherenceAlcohol consumptionHigh-risk clinical profileMarijuana useAlcohol-related negative consequencesUse of cigarettesAlcohol-induced disinhibitionBrief individual counselingClinical profileClinical trialsSelf-report assessmentsNonadherenceHeavy drinkingYoung adultsDemographic characteristicsDrinkersIndividual counselingClinical samplesHeavy alcoholMedicationsDrinking