2019
Histopathology Scoring Systems of Stenosis Associated With Small Bowel Crohn’s Disease: A Systematic Review
Gordon IO, Bettenworth D, Bokemeyer A, Srivastava A, Rosty C, de Hertogh G, Robert ME, Valasek MA, Mao R, Kurada S, Harpaz N, Borralho P, Pai RK, Pai RK, Odze R, Feakins R, Parker CE, Nguyen T, Jairath V, Baker ME, Bruining DH, Fletcher JG, Feagan BG, Rieder F, Consortium S. Histopathology Scoring Systems of Stenosis Associated With Small Bowel Crohn’s Disease: A Systematic Review. Gastroenterology 2019, 158: 137-150.e1. PMID: 31476299, PMCID: PMC7649049, DOI: 10.1053/j.gastro.2019.08.033.Peer-Reviewed Original ResearchConceptsSmall bowel Crohn's diseaseCrohn's diseaseSystematic reviewScoring systemFibromuscular stenosisComputed tomography enterographyMEDLINE of studiesEffective medical therapyCross-sectional imaging techniquesStudy of patientsHistologic scoring systemSemiquantitative histologic evaluationSame scoring systemImportant pathologic componentHistopathology indexSymptomatic stricturesTomography enterographyCommon complicationMedical therapyResection specimenHistologic findingsAntifibrotic agentsFibrotic alterationsHistologic evaluationHistopathologic grading
1996
Rectal afferent function in patients with inflammatory and functional intestinal disorders
Bernstein C, Niazi N, Robert M, Mertz H, Kodner A, Munakata J, Naliboff B, Mayer E. Rectal afferent function in patients with inflammatory and functional intestinal disorders. Pain 1996, 66: 151-161. PMID: 8880836, DOI: 10.1016/0304-3959(96)03062-x.Peer-Reviewed Original ResearchConceptsIrritable bowel syndromeInflammatory bowel diseaseDiarrhea-predominant irritable bowel syndromeViscerosomatic referral patternCrohn's disease patientsIBS patientsDisease patientsCrohn's diseaseMale patientsReferral patternsAfferent pathwaysReflex responsesHealthy male control subjectsTissue irritationAutonomic reflex responsesChronic ileal inflammationLower distension pressuresRapid phasic distensionDorsal horn neuronsVisceral afferent pathwaysIleal Crohn's diseaseFunctional intestinal disordersMale control subjectsSkin conductance responsesBulbospinal inhibition