1992
The pathogenesis of infection with minute virus of mice depends on expression of the small nonstructural protein NS2 and on the genotype of the allotropic determinants VP1 and VP2.
Brownstein D, Smith A, Johnson E, Pintel D, Naeger L, Tattersall P. The pathogenesis of infection with minute virus of mice depends on expression of the small nonstructural protein NS2 and on the genotype of the allotropic determinants VP1 and VP2. Journal Of Virology 1992, 66: 3118-24. PMID: 1373202, PMCID: PMC241074, DOI: 10.1128/jvi.66.5.3118-3124.1992.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornCapsidDNA, ViralEpitopesGenetic VariationImmunohistochemistryMiceMice, Inbred C3HMinute virus of miceMutagenesisNucleic Acid HybridizationParvoviridae InfectionsStructure-Activity RelationshipTissue DistributionViral Core ProteinsViral Nonstructural ProteinsVirulenceConceptsPathogenesis of infectionAsymptomatic infectionMultiple organsViral capsid antigenMesenteric lymph nodesSmooth muscle cellsSame target cellsMVMi infectionLymph nodesCapsid antigenMVMp infectionLethal infectionC3H/Lymphoid cellsTarget organsSimilar dosesAllotropic determinantMinute virusInfectious virusVirus titrationInfectionMuscle cellsMiceTitersTarget cells
1988
Evidence that developmentally regulated control of gene expression by a parvoviral allotropic determinant is particle mediated.
Gardiner E, Tattersall P. Evidence that developmentally regulated control of gene expression by a parvoviral allotropic determinant is particle mediated. Journal Of Virology 1988, 62: 1713-22. PMID: 3357208, PMCID: PMC253210, DOI: 10.1128/jvi.62.5.1713-1722.1988.Peer-Reviewed Original ResearchConceptsProgeny virusIncoming viral capsidInfectious molecular cloneViral transcriptionInfectious centersAllotropic determinantHost cell susceptibilityImmunosuppressive strainAutonomous parvovirus minute virusMolecular cloneCell susceptibilityViral RNASame low levelVirusParvovirus minute virusCell linesRescue of virusPhenotype characteristicViral DNAIntracellular factorsDifferent infectivitySimilar numberFibroblastsMinute virusMouse cell lines