2024
M81 Examining the Relationship of Concurrent Obesity and Tobacco Use Disorder on the Development of Substance Use Disorders and Psychiatric Conditions: Findings From the NESARC-III
Fields L, Roberts W, Schwing I, McCoy M, McKee S. M81 Examining the Relationship of Concurrent Obesity and Tobacco Use Disorder on the Development of Substance Use Disorders and Psychiatric Conditions: Findings From the NESARC-III. Drug And Alcohol Dependence 2024, 260: 110361. DOI: 10.1016/j.drugalcdep.2023.110361.Peer-Reviewed Original ResearchThe role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications
Peltier M, Verplaetse T, Altemus M, Zakiniaeiz Y, Ralevski E, Mineur Y, Gueorguieva R, Picciotto M, Cosgrove K, Petrakis I, McKee S. The role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications. Frontiers In Neuroendocrinology 2024, 73: 101119. PMID: 38184208, PMCID: PMC11185997, DOI: 10.1016/j.yfrne.2023.101119.Peer-Reviewed Original ResearchPosttraumatic stress disorderAlcohol use disorderStress disorderContext of PTSDPTSD/AUDConcurrent posttraumatic stress disorderUnderlying neurobiological mechanismsUse disordersAlcohol-related variablesNeurobiological mechanismsPTSD diagnosisTreatment developmentTreatment implicationsBody of literatureNovel interventionsClinical literatureRole of neurosteroidsDisordersTreatment outcomesYears of researchAlcohol consumptionExogenous pregnenolonePharmacological treatmentBiological variablesAllopregnanolone
2023
Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reduction
2022
Why language matters in alcohol research: Reducing stigma
Shi HD, McKee SA, Cosgrove KP. Why language matters in alcohol research: Reducing stigma. Alcohol Clinical And Experimental Research 2022, 46: 1103-1109. PMID: 35727299, PMCID: PMC9246863, DOI: 10.1111/acer.14840.Peer-Reviewed Original ResearchConceptsAlcohol use disorderUse disordersTreatment outcomesPubMed CentralDrug use disordersQuality of careRate of treatmentAlcohol research communityManual searchWiley Online DatabaseAddictive disordersDisordersTreatment seekingAlcoholicsNational InstituteNIH fundingPercent useInternational SocietyTerminology guidelinesStigmatizing languageAlcohol researchStigmatizing mannerOutcomes
2021
Psychosocial function, legal involvement and violence in mental disorder
Buchanan A, Moore KE, Pittman B, McKee SA. Psychosocial function, legal involvement and violence in mental disorder. European Psychiatry 2021, 64: e75. PMID: 34859762, PMCID: PMC8715282, DOI: 10.1192/j.eurpsy.2021.2250.Peer-Reviewed Original ResearchConceptsPsychosocial functionAssociated Disabilities Interview Schedule-5Mental disordersWorse psychosocial functionDSM-5 categoriesAlcohol use disorderLongitudinal designSchedule 5Significant outcomesLegal involvementUse disordersPersonality disorderEffect sizeDrug abuseNational Epidemiologic SurveyAlcohol abuseMental illnessDisordersAbuseLifetime outcomesPeopleRepresentative sampleRelated conditionsSocial networksForm Health Survey version 2Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders
Peltier MR, Verplaetse TL, Mineur YS, Gueorguieva R, Petrakis I, Cosgrove KP, Picciotto MR, McKee SA. Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders. Neuropharmacology 2021, 187: 108499. PMID: 33600842, PMCID: PMC7992136, DOI: 10.1016/j.neuropharm.2021.108499.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStress-related disordersAlcohol useMajor depressive disorderAlcohol-related disordersAlcohol use disorderPosttraumatic stress disorderStress regulation systemComplex comorbiditiesDepressive disorderProblematic alcohol useUse disordersAlcohol misuseTherapeutic potentialTrauma exposureSubstance abuseStress disorderAnxiety disordersDisordersExposure resultsProgestogensNeurosteroidsNegative affectWomenComorbiditiesMale counterparts
2019
The prevalence of substance use disorders among community-based adults with legal problems in the U.S
Moore KE, Oberleitner L, Pittman BP, Roberts W, Verplaetse TL, Hacker RL, Peltier MR, McKee SA. The prevalence of substance use disorders among community-based adults with legal problems in the U.S. Addiction Research & Theory 2019, 28: 165-172. PMID: 32952490, PMCID: PMC7500665, DOI: 10.1080/16066359.2019.1613524.Peer-Reviewed Original ResearchDrug use disordersSubstance use disordersAlcohol use disorderUse disordersAlcohol-related legal problemsSUD diagnosisSystem involvementAUD diagnosisCurrent AUD diagnosisCurrent alcohol use disorderLifetime alcohol use disorderNational prevalence estimatesStimulant use disorderCommunity-based adultsJustice system involvementLifetime AUD diagnosisDUD diagnosesPrevalence estimatesDiagnosisDisordersAdultsDSM-5Continued needIntervention effortsRepresentative U.S. sampleHigh Risk of Alcohol-Impaired Driving in Adults With Comorbid Alcohol and Substance Use Disorders in the U.S. Population.
Roberts W, Moore KE, Pittman BP, Fillmore MT, McKee SA. High Risk of Alcohol-Impaired Driving in Adults With Comorbid Alcohol and Substance Use Disorders in the U.S. Population. Journal Of Studies On Alcohol And Drugs 2019, 80: 114-119. PMID: 30807283, PMCID: PMC6396510, DOI: 10.15288/jsad.2019.80.114.Peer-Reviewed Original ResearchConceptsSubstance use disordersAlcohol use disorderComorbid substance use disorderUse disordersSUD diagnosisHigh riskAssociated Disabilities Interview Schedule-5Alcohol-impaired drivingPast-year alcohol use disorderSubstance use comorbiditiesNational Epidemiologic SurveyDSM-5 criteriaAlcohol-impaired driving behaviorIncreased oddsComorbid alcoholQuantity/frequencyHigher oddsPast-year drinkersEpidemiologic SurveyRelated conditionsAUD severityU.S. populationDisordersOddsCannabis legalization
2018
Cigarette smoking among those with mental disorders in the US population: 2012–2013 update
Smith PH, Chhipa M, Bystrik J, Roy J, Goodwin RD, McKee SA. Cigarette smoking among those with mental disorders in the US population: 2012–2013 update. Tobacco Control 2018, 29: 29-35. PMID: 30377242, PMCID: PMC11533450, DOI: 10.1136/tobaccocontrol-2018-054268.Peer-Reviewed Original ResearchConceptsSubstance use disordersMental disordersCigarette smokingUse disordersCommon mental disordersPrevalence of lifetimePast-year smokingNational Epidemiologic SurveyRelated Conditions-IIICurrent cigarette useQuit ratioSmoking cessationSmoking prevalenceDaily smokingEpidemiologic SurveySmokingSpecific diagnosisPrevalence estimatesCigarette useUS populationTobacco controlPrevalenceCommon moodDisordersRepresentative estimates
2014
Factor structure and clinical utility of the Beck Depression Inventory in patients with binge eating disorder and obesity
Udo T, McKee SA, Grilo CM. Factor structure and clinical utility of the Beck Depression Inventory in patients with binge eating disorder and obesity. General Hospital Psychiatry 2014, 37: 120-125. PMID: 25537344, PMCID: PMC4361288, DOI: 10.1016/j.genhosppsych.2014.11.011.Peer-Reviewed Original ResearchConceptsBeck Depression InventoryObese patientsMood disordersClinical utilityDepression InventoryDisorder psychopathologyHigh negative predictive valueMajor depressive disorderNegative predictive valueTreatment-seeking obese patientsExcellent internal consistencyDepressive disorderSelf-report questionnairesDepression symptomsPredictive valuePatientsThree-factor structureScreening instrumentDisordersObesityVariable associationsInternal consistencyCrime and Psychiatric Disorders Among Youth in the US Population: An Analysis of the National Comorbidity Survey–Adolescent Supplement
Coker KL, Smith PH, Westphal A, Zonana HV, McKee SA. Crime and Psychiatric Disorders Among Youth in the US Population: An Analysis of the National Comorbidity Survey–Adolescent Supplement. Journal Of The American Academy Of Child & Adolescent Psychiatry 2014, 53: 888-898.e2. PMID: 25062596, PMCID: PMC4137504, DOI: 10.1016/j.jaac.2014.05.007.Peer-Reviewed Original ResearchConceptsNational Comorbidity Survey-Adolescent SupplementPsychiatric disordersPsychiatric comorbidityConduct disorderGreater oddsUS populationMental illnessDSM-IV-based diagnosisLifetime psychiatric disordersSpecific psychiatric disordersMental health servicesAlcohol use disorderRepresentative epidemiological sampleMore diagnosesUse disordersDrug useHealth servicesCommunity settingsLogistic regressionSimilar findingsDiagnosisEpidemiological sampleDisordersOddsSubstantial association
2013
The factor structure of the metabolic syndrome in obese individuals with binge eating disorder
Udo T, McKee SA, White MA, Masheb RM, Barnes RD, Grilo CM. The factor structure of the metabolic syndrome in obese individuals with binge eating disorder. Journal Of Psychosomatic Research 2013, 76: 152-157. PMID: 24439692, PMCID: PMC3953028, DOI: 10.1016/j.jpsychores.2013.10.007.Peer-Reviewed Original ResearchConceptsObese individualsMetabolic syndromeMetabolic measuresHigh-risk populationType II diabetesBlood pressurePatient groupExcess weightSubgroup analysisCardiovascular diseaseRisk populationsGlucose regulationTreatment studiesVARCLUS procedurePopulation studiesFactor structureSyndromeBingeDisordersMetSDiverse populationsFour-factor structureIndividualsStatistical Analysis SystemObesity
2012
How Can We Use Our Knowledge of Alcohol-Tobacco Interactions to Reduce Alcohol Use?
McKee SA, Weinberger AH. How Can We Use Our Knowledge of Alcohol-Tobacco Interactions to Reduce Alcohol Use? Annual Review Of Clinical Psychology 2012, 9: 649-674. PMID: 23157448, PMCID: PMC3651830, DOI: 10.1146/annurev-clinpsy-050212-185549.Peer-Reviewed Original ResearchDoes co-morbid depression alter the inverse relationship between obesity and substance use disorders?
Gearhardt AN, Harrison EL, McKee SA. Does co-morbid depression alter the inverse relationship between obesity and substance use disorders? Drug And Alcohol Dependence 2012, 124: 185-188. PMID: 22285319, PMCID: PMC3359394, DOI: 10.1016/j.drugalcdep.2012.01.002.Peer-Reviewed Original ResearchConceptsSubstance use disordersCo-morbid depressionDrug use disordersUse disordersRisk factorsMajor depressionOverweight/obesity statusCommon risk factorsInverse relationshipNormal weightObesity statusExcess food consumptionPsychiatric disordersDepression disorderObesityDrug useReward circuitryU.S. adultsSubstance useDisordersDepressionAdultsFood consumptionRepresentative sampleCurrent study
2009
Gender Differences in Associations between Lifetime Alcohol, Depression, Panic Disorder, and Posttraumatic Stress Disorder and Tobacco Withdrawal
Weinberger AH, Maciejewski PK, McKee SA, Reutenauer EL, Mazure CM. Gender Differences in Associations between Lifetime Alcohol, Depression, Panic Disorder, and Posttraumatic Stress Disorder and Tobacco Withdrawal. American Journal On Addictions 2009, 18: 140-147. PMID: 19283566, PMCID: PMC2874459, DOI: 10.1080/10550490802544888.Peer-Reviewed Original ResearchConceptsAlcohol abuse/dependenceAbuse/dependenceMajor depressionWithdrawal symptomsPsychiatric statusSmoking relapsePanic disorderIndices of withdrawalStrong associationSmoking cessation interventionNational Comorbidity SurveyPosttraumatic stress disorderGender-specific effectsCessation interventionsNicotine withdrawalTobacco withdrawalRetrospective dataStress disorderLifetime alcoholLonger durationDepressionWithdrawalDisordersRelapseMultiple regression analysis