2024
Evaluation of the study of control arms in randomized clinical trials of cancer.
Jain S, Zauderer M, Sethi T, Schoen M, Rubinstein S, Nguyen R, Nagpal S, Mohan S, Madireddy S, Lythgoe M, Liang W, Kulkarni A, Kothari S, Hilal T, Hadfield M, Goyal G, Ganta T, Dholaria B, Brown A, Warner J. Evaluation of the study of control arms in randomized clinical trials of cancer. Journal Of Clinical Oncology 2024, 42: 11023-11023. DOI: 10.1200/jco.2024.42.16_suppl.11023.Peer-Reviewed Original ResearchRandomized clinical trialsSystemic anti-cancer therapyCancer randomized clinical trialsControl armSuccess rateClinical trials of cancerFisher's exact testAnti-cancer therapyTrial success ratesStudy publication yearExact testPatient convenienceRegimensClinical trialsHighest success rateExperimental armCancer typesCancerContext of treatmentPublication yearTrialsDoseNon-cancerEfficacyDyads
2021
A Multicenter, Real World Analysis of Primary Central Nervous System Lymphoma in Those with and without Human Immunodeficiency Virus
Dittus C, Grover N, Sethi T, Cohen J, Voloschin A, Rabadey J, Tan X, Beaven A, Park S. A Multicenter, Real World Analysis of Primary Central Nervous System Lymphoma in Those with and without Human Immunodeficiency Virus. Blood 2021, 138: 1457. DOI: 10.1182/blood-2021-145133.Peer-Reviewed Original ResearchPrimary CNS lymphomaWhole-brain radiation therapyHD-MTXNon-Hodgkin lymphomaReal-world survivalPCNSL groupMedian PFSAntiretroviral therapyWorse OSPerformance statusEntire cohortAstra ZenecaDiffuse large B-cell lymphoma histologyExact testPrimary central nervous system lymphomaAutologous stem cell transplantExtranodal non-Hodgkin lymphomaCentral nervous system lymphomaLactose dehydrogenaseSignificant differencesCentral nervous system tumorsSeattle GeneticsAdvisory CommitteeDeep structure involvementHD-MTX treatmentNo Difference in Survival Among Black Patients with Mycosis Fungoides and Sézary Syndrome: A Multicenter Retrospective Analysis
Allen P, Goyal S, Greenwell I, Scribner J, Rangarajan S, Mehta A, O'Leary C, Niyogusaba T, Huen A, Switchenko J, Tarabadkar E, Ayers A, Krishnasamy S, Porcu P, Sethi T, Iyer S, Lechowicz M. No Difference in Survival Among Black Patients with Mycosis Fungoides and Sézary Syndrome: A Multicenter Retrospective Analysis. Blood 2021, 138: 2441. DOI: 10.1182/blood-2021-151911.Peer-Reviewed Original ResearchMF/SSWhite blood cell countB patientsNB patientsMedian survivalSézary syndromeInferior survivalSystemic therapyMycosis fungoidesBlack patientsInsurance statusSeattle GeneticsExact testMultivariate Cox proportional hazards modelT-cell receptor clonalityHigh rateCox proportional hazards modelAdvisory CommitteeHigher nodal stageLarge registry studyHigh-risk featuresMulticenter retrospective analysisNumber of comorbiditiesYear of diagnosisKaplan-Meier curves