2024
Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice
Gratton J, Lin M, Yu J, Weiss E, Jiang Z, Fairchild T, Iwakiri Y, Groszmann R, Claffey K, Cheng Y, Sessa W. Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice. Cancer Cell 2024, 42: 1127. PMID: 38821059, DOI: 10.1016/j.ccell.2024.05.009.Peer-Reviewed Original ResearchSafety evaluation of traditional Chinese medicine: new era, new strategy
Zhao X, Bai Z, Zhan X, Wang J, Cheng Y, Xiao X. Safety evaluation of traditional Chinese medicine: new era, new strategy. Acupuncture And Herbal Medicine 2024, 4: 171-175. DOI: 10.1097/hm9.0000000000000119.Peer-Reviewed Original Research
2000
Metabolism and Mode of Inhibition of Varicella-Zoster Virus by l-ÎČ-5-Bromovinyl-(2-hydroxymethyl)-(1,3-dioxolanyl)uracil Is Dependent on Viral Thymidine Kinase
Li L, Dutschman G, Gullen E, Tsujii E, Grill S, Choi Y, Chu C, Cheng Y. Metabolism and Mode of Inhibition of Varicella-Zoster Virus by l-ÎČ-5-Bromovinyl-(2-hydroxymethyl)-(1,3-dioxolanyl)uracil Is Dependent on Viral Thymidine Kinase. Molecular Pharmacology 2000, 58: 1109-1114. DOI: 10.1016/s0026-895x(24)12485-6.Peer-Reviewed Original ResearchViral thymidine kinaseHuman embryonic lungThymidine kinaseVaricella-zoster virus growthMitochondrial DNA synthesisHuman cytosolic thymidine kinaseCytosolic thymidine kinaseNucleoside analogsDeoxyuridine analogsCell growthVirus growthDNA synthesisKinaseE-5-(2-bromovinyl)-2'-deoxyuridineCell culturesInhibition of CEMMonophosphate metaboliteEmbryonic lungTriphosphate metaboliteL-configurationAntiviral activityD-configurationInhibitory mechanismCellsVaricella-zoster virus
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