Seth Herzon, PhD
Milton Harris ’29 Ph.D. Professor of Chemistry
Research & Publications
Biography
News
Extensive Research Description
Anti-Markovnikov Hydration and Reductive Hydration of Alkynes; Diazofluorenes; Guanidinium Alkaloids’ Husbanan and Acutumine Akaloids; Huperzine A; Pleuromutilins; (Pre)Colibactins; Reduction and Hydrofunctionalization of Alkenes by Hydrogen Atom Transfer
Coauthors
Selected Publications
- Intramolecular oxyalkylation of unactivated alkenesXu Z, Airan Y, Tomanik M, Yang A, Bhak N, Herzon S. Intramolecular oxyalkylation of unactivated alkenes. Tetrahedron 2024, 161: 134070. DOI: 10.1016/j.tet.2024.134070.
- Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain CancersHuseman E, Lo A, Fedorova O, Elia J, Gueble S, Lin K, Sundaram R, Oh J, Liu J, Menges F, Rees M, Ronan M, Roth J, Batista V, Crawford J, Pyle A, Bindra R, Herzon S. Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers. Journal Of The American Chemical Society 2024 PMID: 38815248, DOI: 10.1021/jacs.3c06483.
- 1073 GENOME-SCALE CRISPR/CAS9 SCREENING REVEALS THE ROLE OF PSMD4 IN COLIBACTIN-MEDIATED CELL CYCLE ARRESTDougherty M, Hoffmann R, Airan Y, Gharaibeh R, Herzon S, Yang Y, Jobin C. 1073 GENOME-SCALE CRISPR/CAS9 SCREENING REVEALS THE ROLE OF PSMD4 IN COLIBACTIN-MEDIATED CELL CYCLE ARREST. Gastroenterology 2024, 166: s-253. DOI: 10.1016/s0016-5085(24)01066-7.
- An oxidative photocyclization approach to the synthesis of Securiflustra securifrons alkaloidsAlexander B, Bartfield N, Gupta V, Mercado B, Del Campo M, Herzon S. An oxidative photocyclization approach to the synthesis of Securiflustra securifrons alkaloids. Science 2024, 383: 849-854. PMID: 38386756, DOI: 10.1126/science.adl6163.