2025
Trogocytosis-mediated immune evasion in the tumor microenvironment
Kim J, Park S, Kim J, Kim Y, Yoon H, Rayhan B, Jeong J, Bothwell A, Shin J. Trogocytosis-mediated immune evasion in the tumor microenvironment. Experimental & Molecular Medicine 2025, 57: 1-12. PMID: 39741180, PMCID: PMC11799389, DOI: 10.1038/s12276-024-01364-2.Peer-Reviewed Original ResearchConceptsCD4 T cellsT cellsMajor histocompatibility complexTumor microenvironmentImmune evasionMechanisms of immune evasionAnti-tumor immunityImmune regulatory moleculesAntigen-presenting cellsImmune-regulatory moleculesCTLA-4Cell-to-cell interactionsDonor cellsHistocompatibility complexTrogocytosisRecipient cellsTumorMembrane lossMembrane moleculesRegulatory moleculesMicroenvironmentSurface localizationPlasma membraneCellsTrogoptosis
2003
Class II transactivator promoter activity is suppressed through regulation by a trophoblast noncoding RNA1
Geirsson A, Paliwal I, Lynch RJ, Bothwell AL, Hammond GL. Class II transactivator promoter activity is suppressed through regulation by a trophoblast noncoding RNA1. Transplantation 2003, 76: 387-394. PMID: 12883198, DOI: 10.1097/01.tp.0000073612.04525.46.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceDNA MethylationDNA, ComplementaryHeLa CellsHumansLuciferasesMajor Histocompatibility ComplexMolecular Sequence DataNuclear ProteinsNucleic Acid ConformationPromoter Regions, GeneticProtein Structure, TertiaryRNA, UntranslatedSuppression, GeneticTrans-ActivatorsTranscription, GeneticTransfectionTrophoblastsConceptsClass II expressionMHC class IICIITA promoter IVPromoter IVQuantitative polymerase chain reactionMajor histocompatibility complexAllograft tolerancePolymerase chain reactionFluorescence-activated cell sortingCIITA expressionHuman leukocyte antigen-DRClass IIMHC class II expressionClassic major histocompatibility complexChain reactionCell sortingPurposes of transplantationLack expressionHistocompatibility complexNoncoding RNAsII-deficient cellsSelective suppressionPromoter-reporter constructsCIITA promoterInhibitory domain
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply