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YCC Clinical Research Oversight Panels

Protocol Review Committee I (PRC I)

The mission of the Yale Cancer Center (YCC) Protocol Review Committee (PRC), YCC’s Protocol Review and Monitoring System (PRMS), is to provide ongoing review of scientific merit, priorities, and progress of YCC clinical trials. The PRMS has the authority to open protocols that meet the scientific merit and scientific priorities of the YCC and to close protocols that do not demonstrate scientific progress.

Chair: Mario Sznol, MD
Vice-Chair: Hari Deshpande, MD
Contact: Alyssa Dore or Gary Saum
prc.ycc.committees@yale.edu

Protocol Review Committee II (PRC II)

The mission of the Yale Cancer Center (YCC) Protocol Review Committee (PRC), YCC’s Protocol Review and Monitoring System (PRMS), is to provide ongoing review of scientific merit, priorities, and progress of YCC clinical trials. The PRMS has the authority to open protocols that meet the scientific merit and scientific priorities of the YCC and to close protocols that do not demonstrate scientific progress.

Chair: Joseph Kim, MD
Vice-Chair: Raghav Sundar, MD, PhD
Contact: Alyssa Dore or Gary Saum
prc.ycc.committees@yale.edu

Data and Safety Monitoring Committee (DSMC)

The DSMC is an oversight committee, which is an integral component to both the YCC institutional Data and Safety Monitoring Plan and protocol specific data and safety monitoring for trials conducted at YCC. Its purpose is to provide ongoing data and safety monitoring for all interventional cancer clinical trials, which include therapeutic, intervention prevention and intervention supportive care studiesdiv>

Chair: Jeremy Kortmansky, MD
Vice-Chair: Edward Snyder, MD
Contact: Alyssa Dore or Gary Saum
dsmc.ycc.committees@yale.edu

Investigator Initiated Trials Advisory Committee

The YCC IIT Advisory Committee is charged with reviewing all cancer and cancer-related, investigator initiated, clinical trials proposed at Yale specifically.

Chair: William Oh, MD
Contact: Gary Saum or Alyssa Dore
iit.committee@yale.edu