2025
The Use of Acellular Dermal Matrix May Not Increase 30-Day Complications in Direct-to-Implant Breast Reconstruction: A Multi-institutional Analysis of 10,177 Cases.
Knoedler S, Klimitz F, Friedrich S, Schemet L, Broer P, Cherubino M, Könneker S, Kim B, Pomahac B, Kauke-Navarro M. The Use of Acellular Dermal Matrix May Not Increase 30-Day Complications in Direct-to-Implant Breast Reconstruction: A Multi-institutional Analysis of 10,177 Cases. Annals Of Plastic Surgery 2025 PMID: 39874559, DOI: 10.1097/sap.0000000000004234.Peer-Reviewed Original ResearchDirect-to-implant breast reconstructionDirect-to-implantAcellular dermal matrixBreast reconstructionPropensity score matchingHigher risk of short-term complicationsMedical complicationsAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseIncreased 30-day complicationsMultivariate analysisRisk of short-term complicationsQuality Improvement Program databaseThirty-day postoperative complicationsSurgical complication rateIncorporation of acellular dermal matrixScore matchingMulti-institutional analysisMulti-institutional databaseShort-term complicationsComplication ratePostoperative complicationsWound dehiscenceNo significant difference
2024
Protein as a preoperative predictor – Impact of hypoalbuminemia on 30-day outcomes of breast reduction surgery
Knoedler S, Klimitz F, Diatta F, Perozzo F, Sofo G, Alfertshofer M, Cherubino M, Mayer H, Panayi A, Kim B, Pomahac B, Kauke-Navarro M. Protein as a preoperative predictor – Impact of hypoalbuminemia on 30-day outcomes of breast reduction surgery. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024, 100: 144-152. PMID: 39615141, DOI: 10.1016/j.bjps.2024.11.011.Peer-Reviewed Original ResearchBreast reduction surgeryImpact of hypoalbuminemiaReduction surgeryBody mass indexPostoperative complicationsSurgical outcomesMass indexAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseAssociated with adverse surgical outcomesPredictor of postoperative complicationsIncreased risk of complicationsQuality Improvement Program databasePreoperative nutritional assessmentSuperficial incisional infectionNormal albumin levelsBiomarkers of malnutritionHigher body mass indexAdverse surgical outcomesRisk of complicationsImprove surgical outcomesChronic obstructive pulmonary diseaseMultivariate logistic regressionObstructive pulmonary diseaseRisk factors and outcomes after surgery for malignant neoplasm of the parotid gland: An ACS-NSQIP study
Knoedler L, Knoedler S, Hoch C, Safi A, Wollenberg B, Alfertshofer M, Pomahac B, Kauke-Navarro M, Clune J. Risk factors and outcomes after surgery for malignant neoplasm of the parotid gland: An ACS-NSQIP study. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024, 101: 264-274. PMID: 39448324, DOI: 10.1016/j.bjps.2024.09.067.Peer-Reviewed Original ResearchBlood urea nitrogenRisk factorsRenal failureParotid glandMalignant neoplasmsAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseAssociated with higher creatinineNational Surgical Quality Improvement Program databaseMicrosurgical proceduresPre-operative risk factorsQuality Improvement Program databaseRisk of postoperative adverse eventsBlood urea nitrogen levelsHigher ASA classPostoperative adverse eventsOccurrence of complicationsPost-surgical outcomesTumor resectionComplication rateFlap surgeryPostoperative outcomesACS-NSQIPASA classHigher creatinineSurgical Management of Breast Capsular Contracture—A Multi-institutional Data Analysis of Risk Factors for Early Complications
Knoedler S, Knoedler L, Boroumand S, Alfertshofer M, Diatta F, Sofo G, Huelsboemer L, Hansen F, Könneker S, Kim B, Perozzo F, Ayyala H, Allam O, Pomahac B, Kauke-Navarro M. Surgical Management of Breast Capsular Contracture—A Multi-institutional Data Analysis of Risk Factors for Early Complications. Aesthetic Plastic Surgery 2024, 49: 516-527. PMID: 38926252, DOI: 10.1007/s00266-024-04203-x.Peer-Reviewed Original ResearchRisk factorsPostoperative complicationsCC surgeryInpatient settingMedical complicationsAmerican College of Surgeons National Surgical Quality Improvement Program databaseRisk factors of postoperative complicationsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseImplant-based breast surgeryMultivariate analysisPreoperative diagnosis of hypertensionFactors of postoperative complicationsQuality Improvement Program databaseLevel of Evidence IIIThis journalEvidence-Based Medicine ratingsAnalysis of risk factorsDay complication ratesDays follow-upEvidence IIIThis journalLevel of evidenceSurgical adverse eventsDiagnosis of hypertensionMulti-institutional dataTreatment of CC
2023
Racial disparities in surgical outcomes after mastectomy in 223 000 female breast cancer patients: a retrospective cohort study
Knoedler S, Kauke-Navarro M, Knoedler L, Friedrich S, Matar D, Diatta F, Mookerjee V, Ayyala H, Wu M, Kim B, Machens H, Pomahac B, Orgill D, Broer P, Panayi A. Racial disparities in surgical outcomes after mastectomy in 223 000 female breast cancer patients: a retrospective cohort study. International Journal Of Surgery 2023, 110: 684-699. PMID: 38052017, PMCID: PMC10871660, DOI: 10.1097/js9.0000000000000909.Peer-Reviewed Original ResearchAmerican Indian/Alaska Native womenBreast cancer patientsAlaska Native womenSurgical complicationsRadical mastectomyPartial mastectomyCancer patientsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseFemale breast cancer patientsNon-home dischargeRetrospective cohort studyImprovement Program databaseLikelihood of readmissionBreast cancer mortalityBreast cancer surgeryAfrican American patientsAmerican Indians/Alaska NativesBlack/African AmericanNative Hawaiian/Pacific IslanderComplication occurrencePerioperative complicationsPerioperative outcomesAdverse eventsThe surgical patient of yesterday, today, and tomorrow—a time-trend analysis based on a cohort of 8.7 million surgical patients
Knoedler S, Matar D, Friedrich S, Knoedler L, Haug V, Hundeshagen G, Kauke-Navarro M, Kneser U, Pomahac B, Orgill D, Panayi A. The surgical patient of yesterday, today, and tomorrow—a time-trend analysis based on a cohort of 8.7 million surgical patients. International Journal Of Surgery 2023, 109: 2631-2640. PMID: 37788019, PMCID: PMC10498871, DOI: 10.1097/js9.0000000000000511.Peer-Reviewed Original ResearchConceptsSurgical patientsMedian ageMedian BMISurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseACS-NSQIP databaseImprovement Program databaseObesity class IProportion of patientsCohort of patientsPrevalence of diabetesType 2 diabetesGlobal healthcare deliveryFuture surgical careField of surgeryTime trend analysisPatient ageSurgical cohortDiabetes prevalenceProgram databaseSurgical careAmerican CollegeGeneral populationPatients
2022
Perioperative Outcomes and Risk Profile of 4730 Cosmetic Breast Surgery Cases in Academic Institutions: An ACS-NSQIP Analysis
Knoedler S, Kauke-Navarro M, Haug V, Broer P, Pomahac B, Knoedler L, Panayi A. Perioperative Outcomes and Risk Profile of 4730 Cosmetic Breast Surgery Cases in Academic Institutions: An ACS-NSQIP Analysis. Aesthetic Surgery Journal 2022, 43: 433-451. PMID: 36472232, DOI: 10.1093/asj/sjac320.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseCosmetic breast surgeryObstructive pulmonary diseaseRisk factorsSurgical complicationsPulmonary diseaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseMulti-institutional national databaseMultiple proceduresQuality Improvement Program databaseImprovement Program databaseIndependent risk factorCongestive heart failurePositive safety profileObesity class 1ACS-NSQIP AnalysisAnesthesiology scoreBreast surgery casesPerioperative outcomesPerioperative protocolPostoperative outcomesClinical patternHeart failureFemale patientsThe modified 5-item frailty index is a predictor of perioperative risk in breast reconstruction: An analysis of 40,415 cases
Panayi AC, Foroutanjazi S, Parikh N, Haug V, Kauke-Navarro M, Diehm YF, Pomahac B. The modified 5-item frailty index is a predictor of perioperative risk in breast reconstruction: An analysis of 40,415 cases. Journal Of Plastic Reconstructive & Aesthetic Surgery 2022, 75: 2941-2954. PMID: 35599223, DOI: 10.1016/j.bjps.2022.04.035.Peer-Reviewed Original ResearchConceptsImplant-based reconstructionBreast reconstructionMFI-5Unplanned readmissionPostoperative outcomesSurgical complicationsMedical complicationsMFI scoreRisk predictorsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseBreast reconstruction patientsFrailty index-5Powerful risk predictorImprovement Program databasePreoperative risk stratificationStrong risk predictorAutologous breast reconstructionAdverse surgical outcomesType of reconstructionHigh rateFrail patientsHospital stayPerioperative risk
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