Strain‐Dependent Induction of Human Enterocyte Apoptosis by Blastocystis Disrupts Epithelial Barrier and ZO‐1 Organization in a Caspase 3‐ and 9‐Dependent Manner
Wu Z, Mirza H, Teo JD, Tan KS. Strain‐Dependent Induction of Human Enterocyte Apoptosis by Blastocystis Disrupts Epithelial Barrier and ZO‐1 Organization in a Caspase 3‐ and 9‐Dependent Manner. BioMed Research International 2014, 2014: 209163. PMID: 24822183, PMCID: PMC4009109, DOI: 10.1155/2014/209163.Peer-Reviewed Original ResearchConceptsEpithelial barrier compromiseEnterocyte apoptosisHuman colonic epithelial cell line Caco-2Barrier compromiseHuman intestinal epithelial barrier functionIntestinal epithelial barrier functionHuman intestineBlastocystis subtype 7Epithelial cell line Caco-2Caspase-3ST-7Epithelial barrier functionZO-1 organizationStrain-dependent inductionCell line Caco-2Caco-2 monolayersAbdominal painIntestinal symptomsPan-caspase inhibitor Z-VAD-FMKEpithelial permeabilitySubtype 7Subtype 4Epithelial barrierEpithelial resistanceBarrier function
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