He Wang, MD, PhD
Associate Professor of PathologyCards
About
Research
Publications
2024
Vaping and tumor metastasis: current insights and progress
Xi Y, Yang L, Burtness B, Wang H. Vaping and tumor metastasis: current insights and progress. Cancer And Metastasis Reviews 2024, 44: 4. PMID: 39581913, PMCID: PMC11792352, DOI: 10.1007/s10555-024-10221-7.Peer-Reviewed Original ResearchConceptsEpithelial-mesenchymal transitionE-cigsPromote metastasisTumor metastasisCancer metastasisCause of cancer-related mortalityEffects of e-cigsE-cig exposureDormant tumor cellsPrimary cause of cancer-related mortalityPre-metastatic nicheImpact of e-cigarettesTumor cell spreadCancer-related mortalityTraditional cigarette smokingE-cig useLong-term health implicationsIncreased cell migratoryPromote lymphangiogenesisTumor cellsTumor progressionSignificant epigenetic changesMetastatic potentialMetastasisTumorHigher sensitivity of pericardial fluid cytology than biopsy in malignant effusions with potential explanation of false‐negative cytology: A multi‐institutional analysis
Takeda K, Gereg C, Liu X, Ma W, Bearse M, Tang H, Delfino I, Huang E, Lin X, Chandler J, Wang H. Higher sensitivity of pericardial fluid cytology than biopsy in malignant effusions with potential explanation of false‐negative cytology: A multi‐institutional analysis. Cytopathology 2024, 36: 31-40. PMID: 39301772, DOI: 10.1111/cyt.13447.Peer-Reviewed Original ResearchPericardial fluid cytologySensitivity of cytologyMalignant pericardial effusionMulti-institutional analysisFluid cytologyCytology casesPericardial effusionDiagnostic sensitivity of cytologyFalse-negative cytologyFalse-negative resultsSite of originConcurrent biopsyPericardial biopsyHistological subtypesMalignant effusionsHistologic reviewPericardial involvementRetrospective reviewMalignant casesPoor prognosisImmunohistochemistry studiesClinical historyDiagnostic superiorityBiopsyCytologyHigh-Grade Transformation and Carcinosarcoma: A Review of Two Forms of Advanced Progression in the Salivary Gland.
Verma A, Seethala R, Wang H. High-Grade Transformation and Carcinosarcoma: A Review of Two Forms of Advanced Progression in the Salivary Gland. Archives Of Pathology & Laboratory Medicine 2024, 148: 1196-1208. PMID: 38569599, DOI: 10.5858/arpa.2023-0534-ra.Peer-Reviewed Original ResearchConceptsHigh-grade transformationSalivary gland carcinomasPleomorphic adenomaSalivary glandsImmunophenotypic featuresClinical presentationHigh-grade areasMitotic countCellular atypiaCarcinosarcomaDiagnostic criteriaPrognosisRare phenomenonLiterature searchRelevant articlesCarcinomaAdenomasMolecular featuresMolecular characteristicsGlandDedifferentiationAdvanced progressAtypia
2023
Biphenotypic Sinonasal Sarcoma With High-Grade Features: A Diagnostic Challenge
Verma A, Seethala R, Wang H. Biphenotypic Sinonasal Sarcoma With High-Grade Features: A Diagnostic Challenge. International Journal Of Surgical Pathology 2023, 32: 957-961. PMID: 37853732, DOI: 10.1177/10668969231204961.Peer-Reviewed Original ResearchConceptsBiphenotypic sinonasal sarcomaSinonasal sarcomaDiagnostic challengeHigh-grade featuresLow-grade sarcomaMonomorphic spindle cellsSmooth muscle actinElderly female patientsImmunophenotypic featuresSinonasal tractInitial presentationHigh-grade areasFemale patientsSpindle cellsImmunohistochemical featuresDual differentiationLow-grade areasHigh-gradeMuscle actinMyogenic differentiationSarcomaTumorPresentationNeoplasmsThe Milan System for Reporting Salivary Gland Cytopathology and Updates
Wang X, Wang H. The Milan System for Reporting Salivary Gland Cytopathology and Updates. Journal Of Clinical And Translational Pathology 2023, 000: 000-000. DOI: 10.14218/jctp.2023.00011.Peer-Reviewed Original ResearchRecognition and Treatment of Wounds in Persons Using Xylazine: A Case Report From New Haven, Connecticut
Dowton A, Doernberg M, Heiman E, Barelli P, Golden M, Wang H, Leventhal J, Morford K, Sue K. Recognition and Treatment of Wounds in Persons Using Xylazine: A Case Report From New Haven, Connecticut. Journal Of Addiction Medicine 2023, 17: 739-741. PMID: 37934550, DOI: 10.1097/adm.0000000000001198.Peer-Reviewed Original ResearchConceptsOpioid use disorderUse disordersDrug useCase report presentsIndex of suspicionInjection drug useDrug supplyCare management strategiesHarm reduction strategiesOverdose presentationsCutaneous manifestationsWithdrawal syndromeClinical complicationsCase reportIntravenous useWound carePatientsTreatment of woundsInfectious diseasesChronic woundsXylazineSkin woundsWoundsMore reportingDiagnosis
2022
Recent update on human papillomavirus related oropharyngeal carcinoma
Sun P, Gao H, Wang H. Recent update on human papillomavirus related oropharyngeal carcinoma. 中华病理学杂志 2022, 51: 573-575. PMID: 35673738, DOI: 10.3760/cma.j.cn112151-20220106-00009.Peer-Reviewed Original ResearchTargeting hepatic kisspeptin receptor ameliorates non-alcoholic fatty liver disease in a mouse model
Guzman S, Dragan M, Kwon H, de Oliveira V, Rao S, Bhatt V, Kalemba K, Shah A, Rustgi V, Wang H, Bech P, Abbara A, Izzi-Engbeaya C, Manousou P, Guo J, Guo G, Radovick S, Dhillo W, Wondisford F, Babwah A, Bhattacharya M. Targeting hepatic kisspeptin receptor ameliorates non-alcoholic fatty liver disease in a mouse model. Journal Of Clinical Investigation 2022, 132: e145889. PMID: 35349482, PMCID: PMC9106350, DOI: 10.1172/jci145889.Peer-Reviewed Original ResearchConceptsNonalcoholic fatty liver diseaseHigh-fat diet-fed miceNonalcoholic steatohepatitisDiet-fed miceLiver diseaseProgress to nonalcoholic steatohepatitisFatty liver diseaseDiet-induced mouse model of nonalcoholic steatohepatitisWild-type C57BL/6J miceExacerbated hepatic steatosisKisspeptin 1 receptorIncidence of nonalcoholic fatty liver diseaseMouse model of nonalcoholic steatohepatitisPlasma kisspeptin levelsModel of nonalcoholic steatohepatitisDiet-induced mouse modelNon-alcoholic fatty liver diseaseKISS1R signalingType 2 diabetesExcessive hepatic fat accumulationTriglyceride synthesisHepatic fat metabolismKisspeptin levelsTreating nonalcoholic steatohepatitisDecreased fibrosisEmerging Trends in the Pathological Research of Human Papillomavirus-positive Oropharyngeal Squamous Cell Carcinoma
Crane J, Shi Q, Xi Y, Lai J, Pham K, Wang H. Emerging Trends in the Pathological Research of Human Papillomavirus-positive Oropharyngeal Squamous Cell Carcinoma. Journal Of Clinical And Translational Pathology 2022, 2: 31-36. PMID: 36275841, PMCID: PMC9585478, DOI: 10.14218/jctp.2022.00004.Peer-Reviewed Original ResearchOropharyngeal squamous cell carcinomaSquamous cell carcinomaCell carcinomaHuman papillomavirusHuman papillomavirus-positive oropharyngeal squamous cell carcinomaHPV-positive oropharyngeal squamous cell carcinomaHPV-negative oropharyngeal squamous cell carcinomaActive human papillomavirusNew targetsLong-term survivalPotential new targetsDefinitive treatmentHPV 16Treatment optionsSurvival prognosisTumor prognosisAdvanced stageHealth responsePrecision treatmentPrecision medicinePatientsCarcinomaPrognosisTreatmentPathological researchSub-specialty Updates on Diagnostic Anatomical and Clinical Pathology
Zhang L, Wang H. Sub-specialty Updates on Diagnostic Anatomical and Clinical Pathology. Journal Of Clinical And Translational Pathology 2022, 2: 1-2. DOI: 10.14218/jctp.2022.00006.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- March 01, 2024
Connecticut Society of Pathologists' Educational Meeting Draws Pathologists from Across the State
- December 19, 2023
Yale Pathologists Lead Effort to Revitalize Connecticut Society of Pathologists
- June 21, 2022
He Wang, MD, PhD, Named Director of New Cardiovascular Pathology Section in Pathology
- March 18, 2022
Yale Pathologists Participating in Annual USCAP Meeting to Share Research, Advancements
Get In Touch
Contacts
Email
Mailing Address
Yale University
Dept of Pathology, P.O. BOX 208023
New Haven, CT 06520
United States
Locations
Yale New Haven Hospital Saint Raphael Campus
Academic Office
1450 Chapel Street, Ste VG43
New Haven, CT 06511