MKP1 promotes nonalcoholic steatohepatitis by suppressing AMPK activity through LKB1 nuclear retention
Qiu B, Lawan A, Xirouchaki C, Yi J, Robert M, Zhang L, Brown W, FernĂĄndez-Hernando C, Yang X, Tiganis T, Bennett A. MKP1 promotes nonalcoholic steatohepatitis by suppressing AMPK activity through LKB1 nuclear retention. Nature Communications 2023, 14: 5405. PMID: 37669951, PMCID: PMC10480499, DOI: 10.1038/s41467-023-41145-5.Peer-Reviewed Original ResearchMeSH KeywordsAMP-Activated Protein KinasesAnimalsInflammationMaleMiceMitogen-Activated Protein Kinase 14Non-alcoholic Fatty Liver DiseasePhosphorylationProtein Serine-Threonine Kinases
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