2014
Comorbidity, Chemotherapy Toxicity, and Outcomes Among Older Women Receiving Adjuvant Chemotherapy for Breast Cancer on a Clinical Trial: CALGB 49907 and CALGB 361004 (Alliance)
Klepin HD, Pitcher BN, Ballman KV, Kornblith AB, Hurria A, Winer EP, Hudis C, Cohen HJ, Muss HB, Kimmick GG. Comorbidity, Chemotherapy Toxicity, and Outcomes Among Older Women Receiving Adjuvant Chemotherapy for Breast Cancer on a Clinical Trial: CALGB 49907 and CALGB 361004 (Alliance). JCO Oncology Practice 2014, 10: e285-e292. PMID: 25074878, PMCID: PMC4161730, DOI: 10.1200/jop.2014.001388.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAntineoplastic AgentsBreast NeoplasmsCapecitabineChemotherapy, AdjuvantComorbidityDeoxycytidineDisease-Free SurvivalFemaleFluorouracilHumansKaplan-Meier EstimateMultivariate AnalysisProportional Hazards ModelsQuality of LifeRegression AnalysisSurveys and QuestionnairesTreatment OutcomeConceptsOverall survivalAdjuvant chemotherapyBurden scoreBreast cancerOlder womenShorter OSClinical trialsEarly-stage breast cancerCox proportional hazards modelStandard adjuvant chemotherapyNumber of comorbiditiesHazard of deathPhysical health subscaleOlder Americans ResourcesProportional hazards modelCALGB 49907Chemotherapy toxicityReceptor statusComorbid conditionsTumor sizeHealth subscaleGrade 3ComorbiditiesCommon conditionHazards modelAssociations among survivorship care plans, experiences of survivorship care, and functioning in older breast cancer survivors: CALGB/Alliance 369901
Faul LA, Luta G, Sheppard V, Isaacs C, Cohen HJ, Muss HB, Yung R, Clapp JD, Winer E, Hudis C, Tallarico M, Wang J, Barry WT, Mandelblatt JS. Associations among survivorship care plans, experiences of survivorship care, and functioning in older breast cancer survivors: CALGB/Alliance 369901. Journal Of Cancer Survivorship 2014, 8: 627-637. PMID: 24917307, PMCID: PMC4386650, DOI: 10.1007/s11764-014-0371-5.Peer-Reviewed Original ResearchConceptsOlder breast cancer survivorsSurvivorship care plansBreast cancer survivorsCare plansCancer survivorsSCP receiptSurvivorship careOlder survivorsBreast cancer followCooperative group sitesNonmetastatic breast cancerPatient-reported outcomesCancer followSymptom burdenComorbid conditionsRecurrence surveillanceCancer patientsCancer sequelaePrimary careMethodsThree hundredBreast cancerCancer worryLower oddsOlder womenTelephone interviews
2012
Comorbidity, chemotherapy toxicity, and outcomes among older women receiving adjuvant chemotherapy for breast cancer (BC).
Klepin H, Pitcher B, Ballman K, Kimmick G, Kornblith A, Cohen H, Hurria A, Winer E, Hudis C, Muss H. Comorbidity, chemotherapy toxicity, and outcomes among older women receiving adjuvant chemotherapy for breast cancer (BC). Journal Of Clinical Oncology 2012, 30: 6015-6015. DOI: 10.1200/jco.2012.30.15_suppl.6015.Peer-Reviewed Original ResearchAdjuvant chemotherapyBreast cancerOverall survivalBurden scoreOlder womenShorter OSEarly-stage breast cancerAdditional comorbid conditionsLeukemia Group BStandard adjuvant chemotherapyBetter functional statusStage breast cancerHazard of deathProportional hazards modelComorbidity burdenChemotherapy toxicityPrimary outcomePulmonary diseaseReceptor statusClinical outcomesComorbid conditionsComorbidity measuresNode statusSurvival outcomesTumor size