2007
Blood Vessel Morphologic Changes Depicted with MR Angiography during Treatment of Brain Metastases: A Feasibility Study1
Bullitt E, Lin NU, Smith JK, Zeng D, Winer EP, Carey LA, Lin W, Ewend MG. Blood Vessel Morphologic Changes Depicted with MR Angiography during Treatment of Brain Metastases: A Feasibility Study1. Radiology 2007, 245: 824-30. PMID: 17954616, PMCID: PMC2615672, DOI: 10.1148/radiol.2453061889.Peer-Reviewed Original ResearchConceptsBrain metastasesVessel tortuosityTumor treatment responseMR angiographyBreast cancerTreatment responseMorphologic changesBrain MR angiographyTreatment failure 1Vascular morphologic changesInstitutional review board approvalHealthy control subjectsReview board approvalMagnetic resonance angiographyHIPAA-compliant studyLapatinib therapyNineteen patientsClinical courseControl subjectsAbnormal vesselsTumor volumeFailure 1Board approvalPatientsResonance angiography
2006
Superiority of bi-dimensional measurements compared to RECIST in measuring response of metastatic brain tumors
Kilpatrick M, Linn N, Smith J, Winer E, Bullitt E, Carey L, Ewend M. Superiority of bi-dimensional measurements compared to RECIST in measuring response of metastatic brain tumors. Journal Of Clinical Oncology 2006, 24: 1542-1542. DOI: 10.1200/jco.2006.24.18_suppl.1542.Peer-Reviewed Original ResearchMetastatic brain tumorsProgressive diseaseRECIST criteriaBrain tumorsDana-Farber/Harvard Cancer CenterProspective phase II studyMetastatic breast cancer lesionsPhase II studyBreast cancer lesionsVolume measurementsStable diseaseBrain metastasesII studyPartial responseClinical benefitTumor sizeCancer CenterTumor responseMetastatic natureTumor volumeRECISTBi-dimensional measurementsBidimensional criteriaCancer lesionsResponse rate