2016
Data publication with the structural biology data grid supports live analysis
Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Christopher Fromme J, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P. Data publication with the structural biology data grid supports live analysis. Nature Communications 2016, 7: 10882. PMID: 26947396, PMCID: PMC4786681, DOI: 10.1038/ncomms10882.Peer-Reviewed Original ResearchMeSH KeywordsCrystallography, X-RayDatabases, GeneticInternetMacromolecular SubstancesPublicationsSoftwareConceptsData gridData publicationData setsGlobal data accessPrimary experimental data setsBiomedical data setsData accessExperimental data setsImage dataDissemination systemPilot collectionProcessing methodsGridSetData analysisAccessParadigm shiftDynamic bodyScientific publicationsSBDGServicesInformationCrystallographic data sets
1995
Kinetic Characterization of Channel Impaired Mutants of Tryptophan Synthase (∗)
Anderson K, Kim A, Quillen J, Sayers E, Yang X, Miles E. Kinetic Characterization of Channel Impaired Mutants of Tryptophan Synthase (∗). Journal Of Biological Chemistry 1995, 270: 29936-29944. PMID: 8530393, DOI: 10.1074/jbc.270.50.29936.Peer-Reviewed Original ResearchBinding SitesCarbon RadioisotopesGlycerophosphatesIndolesKineticsMacromolecular SubstancesMathematicsModels, TheoreticalMutagenesis, Site-DirectedPoint MutationProtein ConformationRadioisotope Dilution TechniqueRecombinant ProteinsSalmonella typhimuriumSerineStructure-Activity RelationshipTryptophan SynthaseReevaluating glyphosate as a transition-state inhibitor of EPSP synthase: identification of an EPSP synthase.EPSP.glyphosate ternary complex.
Sammons R, Gruys K, Anderson K, Johnson K, Sikorski J. Reevaluating glyphosate as a transition-state inhibitor of EPSP synthase: identification of an EPSP synthase.EPSP.glyphosate ternary complex. Biochemistry 1995, 34: 6433-40. PMID: 7756274, DOI: 10.1021/bi00019a024.Peer-Reviewed Original ResearchMeSH Keywords3-Phosphoshikimate 1-CarboxyvinyltransferaseAlkyl and Aryl TransferasesGlycineKineticsMacromolecular SubstancesProtein BindingRecombinant ProteinsTransferasesConceptsEPSP synthaseTernary complexShikimate 3-phosphateSteady-state kineticsEnzyme active siteTransition-state analogSubstrate turnoverSynthase reactionTransition-state inhibitorsEnzymeAssociated with PEPUncompetitive inhibitorBinding resultsSynthaseActive siteFluorescence titration experimentsShikimateOxonium ionsTurnoverInteraction of glyphosateTitration experiments