Yale SPORE in Lung Cancer News

Formerly called the Conclave Awards, the 2025 Spring Yale Cancer Center awards honored research, clinical expertise, and support staff at the Hotel Marcel, New Haven on April 1, 2025.

Publications regarding cancer attributed to first- and last-authors of published papers

A new study from scientists at Yale School of Medicine has identified N-acetyltransferase 10 (NAT10), an enzyme highly expressed in brain metastasis, as a driver of brain metastasis. NAT10 primarily functions by adding acetyl groups to RNA molecules, regulating their function, stability or translation.

Cancer research flourished with fast-paced breakthroughs in the last 15 to 20 years, and it should continue to now, the most recent director of the National Cancer Institute (NCI) told a packed audience Tuesday at a special Yale Cancer Center Grand Rounds. In her hour-long talk as the presenter of the annual Paul Calabresi Memorial Lectureship during YCC Grand Rounds, W. Kimryn Rathmell, MD, PhD, said In many ways, “we are living in a phased shift in how we are thinking about and doing our science."

Twelve Yale School of Medicine faculty members are among the leading experts in science, technology, engineering, mathematics, and medicine newly elected to the Connecticut Academy of Science and Engineering.

A new study led by Dr. Roy Herbst, deputy director of Yale Cancer Center, found evidence to support the value of a tool that measures the presence of cancer-derived molecules in the blood of patients with lung cancer, years after their treatment.

On Sunday, March 16, 2025, Dr. Eric Winer interviewed Roy Herbst, MD, PhD, Ensign Professor of Medicine (Medical Oncology) and Professor of Pharmacology, Deputy Director of Yale Cancer Center, and Chief of Hematology/Medical Oncology at Yale Cancer Center and Smilow Cancer Hospital.

Researchers in the Nguyen Lab at Yale School of Medicine focus on understanding how lung cancer metastasizes to distant organs, including the brain, and how cancer cells that reach the brain become resistant to drug therapy.

The National Cancer Institute has awarded Lisa Fucito, PhD, associate professor of psychiatry, a $3.4 million grant to test if varenicline, a medication FDA-approved for smoking cessation, is effective for helping people quit vaping.