Use Pre- and Intra-Operative Data To Predict Probability of Positive Non-Sentinel Lymph Nodes.
Chagpar A, Blumencranz P, Whitworth P, Deck K, Rosenberg A, Simmons R, Reintgen D, Beitsch P, Julian T, Saha S, Mamounas E, Giuliano A, Cook E, Wang S. Use Pre- and Intra-Operative Data To Predict Probability of Positive Non-Sentinel Lymph Nodes. Cancer Research 2009, 69: 302-302. DOI: 10.1158/0008-5472.sabcs-09-302.Peer-Reviewed Original ResearchAxillary node dissectionNon-SLN metastasisTumor sizeIntra-operative dataBLN AssayPositive SLNMedian numberLogistic regression modelsPositive non-sentinel lymph nodesSentinel lymph node-positive patientsCompletion axillary node dissectionFrozen sectionsLymph node-positive patientsNon-sentinel lymph nodesStepwise logistic regression modelFurther positive nodesNon-SLN statusMedian tumor sizeNode-positive patientsPositive rateTumor size dataSignificant predictorsCohort of interestNode dissectionPositive nodesUse of intraoperative breast cancer sentinel lymph node (SLN) assay to predict of ≥4 positive (+) lymph nodes (LN)
Chagpar A, Blumencranz P, Whitworth P, Deck K, Rosenberg A, Simmons R, Reintgen D, Beitsch P, Saha S, Julian T. Use of intraoperative breast cancer sentinel lymph node (SLN) assay to predict of ≥4 positive (+) lymph nodes (LN). Journal Of Clinical Oncology 2009, 27: 530-530. DOI: 10.1200/jco.2009.27.15_suppl.530.Peer-Reviewed Original ResearchSentinel lymph nodesLymph nodesFinal pathologyTumor sizeMedian cycle timeBreast cancer sentinel lymph nodesTotal lymph nodesMedian tumor sizePositive lymph nodesImmediate breast reconstructionHematoxylin-eosin stainingReceiver operator curveCohort of interestBLN AssayQuantitative RT-PCRSLN metastasisProspective studyBreast reconstructionReal-time RT-PCR analysisMedian numberClinical utilityRadiation therapyPatientsMultivariate analysisMammaglobin