Differences in biological activity among batches of lyophilized tice Bacillus Calmette-Guérin and their association with clinical course in Stage I lung cancer.
Bennett J, Gruft H, McKneally M, Zelterman D, Crispen R. Differences in biological activity among batches of lyophilized tice Bacillus Calmette-Guérin and their association with clinical course in Stage I lung cancer. Cancer Research 1983, 43: 4183-90. PMID: 6347367.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDrug Evaluation, PreclinicalFibrosarcomaFreeze DryingImmunotherapyLung NeoplasmsMaleMiceMice, Inbred StrainsMycobacterium bovisNeoplasm StagingSarcoma, ExperimentalConceptsBacillus Calmette-GuérinLung Cancer Study GroupCancer Study GroupTumor cellsCalmette-GuérinStudy groupNorth American Lung Cancer Study GroupStage I lung cancer patientsStage I lung cancerI lung cancerAntitumor activityDisease-free intervalProlongation of survivalLung cancer patientsFuture clinical trialsAdjuvant therapyClinical courseCancer patientsLung cancerClinical trialsSolid tumor growthTumor growthTumor colonizationPreclinical testingLethal dose