2005
Altered Localization of p120 Catenin During Epithelial to Mesenchymal Transition of Colon Carcinoma Is Prognostic for Aggressive Disease
Bellovin DI, Bates RC, Muzikansky A, Rimm DL, Mercurio AM. Altered Localization of p120 Catenin During Epithelial to Mesenchymal Transition of Colon Carcinoma Is Prognostic for Aggressive Disease. Cancer Research 2005, 65: 10938-10945. PMID: 16322241, DOI: 10.1158/0008-5472.can-05-1947.Peer-Reviewed Original ResearchConceptsSurvival timeMesenchymal transitionLymph node metastasisColorectal cancer progressionPoor patient outcomesE-cadherinLate-stage tumorsPatient survival timePost-EMT cellsP120ctn expressionAltered localizationLymph nodesNode metastasisAggressive diseaseTumor stagePrimary tumorTumor necrosisColorectal carcinomaPatient outcomesColon carcinoma cellsE-cadherin lossCytoplasmic stainingColon carcinomaCancer progressionCarcinoma cells
2001
Use of magnetic enrichment for detection of carcinoma cells in fluid specimens
Kielhorn E, Schofield K, Rimm DL. Use of magnetic enrichment for detection of carcinoma cells in fluid specimens. Cancer 2001, 94: 205-211. PMID: 11815978, DOI: 10.1002/cncr.10193.Peer-Reviewed Original ResearchConceptsFluid specimensEpithelial cellsCarcinoma cellsCell enrichmentDetection of malignancyDetermination of malignancyRare epithelial cellsE-cadherin stainingPleural effusionAccurate stagingMetastatic carcinomaCytologic evaluationCytologic diagnosisMedical conditionsAtypical casesMalignant casesMalignant cellsInsufficient cellsNegative casesImmunomagnetic enrichmentAscites fluidMalignancyImmunomagnetic selectionCommon event