2020
Association between low estrogen receptor positive breast cancer and staining performance
Caruana D, Wei W, Martinez-Morilla S, Rimm DL, Reisenbichler ES. Association between low estrogen receptor positive breast cancer and staining performance. Npj Breast Cancer 2020, 6: 5. PMID: 32047851, PMCID: PMC7002746, DOI: 10.1038/s41523-020-0146-2.Peer-Reviewed Original ResearchER expressionER- tumorsBreast carcinomaTissue microarrayNormal epitheliumEstrogen receptor-positive breast cancerER casesReceptor-positive breast cancerControl patient populationER-positive tumorsEstrogen receptor expressionPositive breast cancerMean optical densityBackground epitheliumPositive tumorsControl cohortPatient populationControl tumorsReceptor expressionBenign epitheliumBreast cancerRare caseNormal ductsER stainingTumors
2009
Preliminary Comparison between AQUA and Centralised ER/PgR Analysis within the TEAM Pathology Study.
Bartlett J, Rimm D, Brookes C, Dolled-Filhart M, Robson T, van de Velde C, Billingham L, Campbell F, Hasenburg A, Hille E, Kieback D, Putter H, Markopoulos C, Christiansen J, Gustavson M, Mallon E, Meershoek-Klein Kranenburg E, Parideans R, Seynaeve C, Rea D. Preliminary Comparison between AQUA and Centralised ER/PgR Analysis within the TEAM Pathology Study. Cancer Research 2009, 69: 3045-3045. DOI: 10.1158/0008-5472.sabcs-09-3045.Peer-Reviewed Original ResearchER/PgRER expressionImmunohistochemical assaysAQUA scoreExemestane Adjuvant Multinational (TEAM) trialHigh ER expressionTeam patientsPatient prognosisAromatase inhibitorsMultinational trialOutcome dataPathology studiesCancer ResAQUA technologyIHCPreliminary dataPatientsRegression analysisPGR analysisFurther dataPgRImage analysisIncremental increaseScoresMultiple coresPredictive value of p27 for the benefit of adjuvant anthracycline-based chemotherapy in early breast cancer.
Conforti R, Moeder C, Tomasic G, Boulet T, Nahta R, Yuan L, Spielmann M, Delaloge S, Michiels S, Rimm D, Esteva F, Andre F. Predictive value of p27 for the benefit of adjuvant anthracycline-based chemotherapy in early breast cancer. Cancer Research 2009, 69: 6063. DOI: 10.1158/0008-5472.sabcs-6063.Peer-Reviewed Original ResearchEarly breast cancerHazard ratioInstitut Gustave RoussyPredictive valueOverall survivalControl armBreast cancerAdjuvant anthracycline-based chemotherapyHR of deathCytoplasmic expressionTumor samplesAdjusted hazard ratioAnthracycline-based chemotherapyDisease-free survivalBreast cancer patientsCox regression modelInteraction p valueUnit increaseAdjuvant anthracyclinesAdjuvant treatmentCyclin-dependent kinase inhibitorEGFR tumorsER expressionRandomized trialsPredictive factors